Protein Alignment Ir76a and Grik5

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 683
• Identity: 122/683 - (17%)
• Similarity: 206/683 - (30%)
• Gaps: 256/683 - (37%)

  Fly    40 RLETVHPMPLIIMDWHRWANRSDQDVYDYKIKED------EFEGKGIPYNDWTLRLTVAIERSHC 98
            |.:.:...||.....:.|.:.:....|...::.|      ||..||...| :|||:.....:.|.
Mouse   346 RSQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTN-YTLRILEKSRQGHR 409

  Fly    99 ETFIAFQEQIPEFARYFYHASIYSIWRSLRNRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITS 163
            |                     ..:|.|.|...|...|.:                     :..|
Mouse   410 E---------------------IGVWYSNRTLAMNATTLD---------------------INLS 432

  Fly   164 QYLNSSTFEIKTNRFVGPRNFNKNPEPVEFYILQR--FDAKGTKATWETQSAMSSKMRNLKGREV 226
            |.|.:.|..:.|        ..:||     |:::|  |.|                   |.|.|
Mouse   433 QTLANKTLVVTT--------ILENP-----YVMRRPNFQA-------------------LSGNE- 464

  Fly   227 VIGIFDYKPFMLLDYEKPPLYYDRFMNTTDVTIDGTDIQLMLIFCELYNCTIQVDTSEPYDWGDI 291
                                   ||        :|..:.::....||.....::...|...:|..
Mouse   465 -----------------------RF--------EGFCVDMLRELAELLRFRYRLRLVEDGLYGAP 498

  Fly   292 YLNASGYGLVGMILDRRN-DYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPA-PNRLISWTLLL 354
            ..|.|..|:||.:::|:. |..|....:..|..:.:|.:......|::.|... ..|...:...|
Mouse   499 EPNGSWTGMVGELINRQKADLAVAAFTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFL 563

  Fly   355 RPFQFVLWMCVMLCLLLESLALGITRR-----W--EHSSVAA-----------GNS-WISSLRFG 400
            .||...:|:.::|..|..|..|.:..|     |  .|..:.|           ||| |.
Mouse   564 DPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPHPCLRARPHILENQYTLGNSLWF------ 622

  Fly   401 CISTLKLFVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFD 465
               .:..|:.|.:..:..:.:.|.|....:...:|:.:.|:..|||.||:..:|...:|...|.|
Mouse   623 ---PVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLAD 684

  Fly   466 HKLIWTGTSQAWIT-------------------------------------TIDERSADPVLLGL 493
            ...|..||..|..|                                     .::.|.|..:...:
Mouse   685 QTNIEYGTIHAGSTMTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVLNSRYAFLLESTM 749

  Fly   494 MEHYRVYDANLISAFSHTEQMGFVVERLQFG---HLGN----------TELIENDALKRLKLMVD 545
            .|::|..:.||       .|:|.:::...:|   .||:          .:|.||:.|:.||
Mouse   750 NEYHRRLNCNL-------TQIGGLLDTKGYGIGMPLGSPFRDEITLAILQLQENNRLEILK---- 803

  Fly   546 DIYFAFTVAFVPRLWPHLNAYNDFILAWHSSGFDKFWEWKIAAEYMNAHRQNRIVASEKTNLDIG 610
                        |.|            |......|          ...||..
Mouse   804 ------------RKW------------WEGGRCPK----------EEDHRAK------------- 821

  Fly   611 PVKLGIDNFIGLILLWCFGMICSLLTFLGE-LW 642
              .||::|..|:.::...|:|.::...:.| :|
Mouse   822 --GLGMENIGGIFVVLICGLIIAVFVAVMEFIW 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	20/99 (20%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:419667	86/478 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846641
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840