Protein Alignment Ir76a and Grik4

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_780690.2
• Gene: Grik4 / 110637
• MGIID: 95817
• Length: 956
• Species: Mus musculus
• Alignment Length: 612
• Identity: 114/612 - (18%)
• Similarity: 209/612 - (34%)
• Gaps: 181/612 - (29%)

  Fly   119 SIYSIWRSLR--NRFMFVYTKEFEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRFVGP 181
            ::|::..:::  ||     ::|...|..|..|..|:|...:::    .||..    ::.....|.
Mouse   311 AVYAVVTAVQELNR-----SQEIGVKPLSCGSAQIWQHGTSLM----NYLRM----VELEGLTGH 362

  Fly   182 RNFNKNPEPVEFYI-LQRFDAKGTK--ATWETQSAMSSKMR--------NLKGREVVIGIFDYKP 235
            ..||...:...:.: :.:|...|.:  ..|.....:|...|        :|....:|:......|
Mouse   363 IEFNSKGQRSNYALKILQFTRNGFQQIGQWHVAEGLSMDSRLYASNISDSLFNTTLVVTTILENP 427

  Fly   236 FMLLDYEKPPLY-YDRFMNTTDVTIDGTDIQLMLIFCEL--YNCTIQVDTSEPYDWGDIYLNASG 297
            :::|......:. .||:        :|..:.::....|:  :|..|::.....|  |....|.:.
Mouse   428 YLMLKGNHQEMEGNDRY--------EGFCVDMLKELAEILRFNYKIRLVGDGVY--GVPEANGTW 482

  Fly   298 YGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPA-PNRLISWTLLLRPFQFVL 361
            .|:||.::.|:.|..|.|:.:..|..:.:|.:......|::.|... ..|...:...|.||...:
Mouse   483 TGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRRPGYFSFLDPFSPGV 547

  Fly   362 WMCVMLCLLLESLALGITRR-----W--EH-----------SSVAAGNS-WISSLRFGCISTLKL 407
            |:.::|..|..|..|.:..|     |  .|           :..:.||| |.         .:..
Mouse   548 WLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWF---------PVGG 603

  Fly   408 FVNQSTNYVTSSYALRTVLVASYMIDIILTTVYSGGLAAILTLPTLEEAADSRQRLFDHKLIWTG 472
            |:.|.:.....:.:.|.|....:...:|:.:.|:..|||.||:..:|...:|...|.|...|..|
Mouse   604 FMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESVDDLADQTAIEYG 668

  Fly   473 T------------------SQAW-----------ITTIDE------RSADPVLL--GLMEHYRVY 500
            |                  .:.|           :.:.:|      .|....||  .:.|:||..
Mouse   669 TIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAFLLESTMNEYYRQR 733

  Fly   501 DANLISAFSHTEQMGFVVERLQFG-------------HLGNTELIENDALKRLKLMVDDIYFAFT 552
            :.||       .|:|.:::...:|             .|...:|.||:.|:.||
Mouse   734 NCNL-------TQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILK----------- 780

  Fly   553 VAFVPRLWPHLNAYNDFILAWHSSGFDKFWE-WKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGI 616
                 |.|                     || .|...|  ..||..               .||:
Mouse   781 -----RKW---------------------WEGGKCPKE--EDHRAK---------------GLGM 802

  Fly   617 DNFIGLILLWCFGMICSL-LTFLGELW 642
            :|..|:.::...|:|.:: :..|..||
Mouse   803 ENIGGIFVVLICGLIVAIFMAMLEFLW 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
Grik4	NP_780690.2	Periplasmic_Binding_Protein_type1	24..402	CDD:385651	18/103 (17%)
		PBP2_iGluR_kainate_KA1	415..785	CDD:270442	79/432 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..956

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846216
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840