Protein Alignment Ir76a and grin3b

DIOPT Version :10

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 610
• Identity: 121/610 - (19%)
• Similarity: 214/610 - (35%)
• Gaps: 186/610 - (30%)

  Fly   136 TKEFEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRFVGPRNFNKNPEPVEFYILQRFD 200
            ||: .:...|||               |::|.:::|..:|.:.....|..........:.|.| |
 Frog   330 TKQ-NESSGSYL---------------SRFLANTSFSGQTGQIYVSNNLIHTEHHYRIWSLVR-D 377

  Fly   201 AKGTKATWETQSA-MSSKMRNLKGREVVIGIFDYKPFMLLDYEKPPLYYDR------------FM 252
            :.| ..||.|... ...||      ||..|::..:   :..:|..|..:.|            |:
 Frog   378 SLG-DPTWVTVGGWRQGKM------EVEEGLWQSR---IQQWEPAPGGFARTKLRVVTLVEHPFV 432

  Fly   253 NTTDVTIDGT--------------DIQLMLIFCEL-----------------YNCTIQVDTSEP- 285
            .|.:|..||:              ...|.::|.||                 |...:....||.
 Frog   433 FTREVDADGSCPAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCIDLLEKLSEDL 497

  Fly   286 -YDWGDIYLNASG-YGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLV--PAPNR 346
             :|: ::|:...| ||.      |:.|...|.:........:|.:|.|...|..:.::  .:|..
 Frog   498 RFDF-ELYIVGDGKYGA------RKGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFTSPFY 555

  Fly   347 LISWTLLLR-------------PFQFVLWMCVMLCLLLESLAL---------GITRRWEHSSVAA 389
            ..|..:|:|             |..:.:|:.:.:.|.:.:|.|         |:|....:.:...
 Frog   556 STSLGILVRMRDTASPIGAFMWPLHWSMWVGIFVALHITALFLTFYEWKSPFGMTPHGRNRTKIF 620

  Fly   390 GNSWISSLRFGCISTLKLFVNQSTNYVTSSYALRTVLVASYMIDIILT-TVYSGGLAAILTLPTL 453
              |:.|:|.. |.:.|   ..::.:..|.......||:..:.|..:|. :.|:..|||::.....
 Frog   621 --SYSSALNL-CYAIL---FGRTVSSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGDKT 679

  Fly   454 EEAADSRQRLFDHKL-----------IWTGTSQAWITTIDERSADPVLLGLMEHYRVYDANLISA 507
            .||...   :.|.||           :|..:::.:|     :.:.|.:
 Frog   680 FEALSG---IHDPKLHHPSQGFRFGTVWESSAEQYI-----KKSFPEM----------------- 719

  Fly   508 FSHTEQMGFVVERLQFG-HLGNTE------LIENDALKRLKLMVDDIYFAFTVA----------F 555
              |.....|.|.....| ||..|:      .|.:.||...::.:|......|:.          .
 Frog   720 --HNYMRKFSVPATSDGVHLLKTDPPTLNAFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIG 782

  Fly   556 VPRLWPHLNAYNDFILAWHSSGF-----DKFWEWKIAAEYMNAHRQNRIVASEKTNLDIGPVKLG 615
            :|:..|..:..::||..:.||||     ||:::.....:        |:.|..:|      :::|
 Frog   783 LPQNSPLTSNISEFISRYKSSGFMDTLHDKWYKMVPCGK--------RVYAVTET------LQMG 833

  Fly   616 IDNFIGLILLWCFGMICSLLTFLGE 640
            |.:|.||.:|.|.|...||||.|.|
 Frog   834 IYHFSGLFVLLCIGFCGSLLTSLME 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	22/95 (23%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	80/435 (18%)
		Lig_chan	580..847	CDD:459656	60/313 (19%)