Protein Alignment Ir76a and grin2b

DIOPT Version :9

• Sequence 1: NP_001097647.3
• Gene: Ir76a / 40157
• FlyBaseID: FBgn0260874
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_017948700.2
• Gene: grin2b / 100490580
• XenbaseID: XB-GENE-949327
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 677
• Identity: 121/677 - (17%)
• Similarity: 226/677 - (33%)
• Gaps: 222/677 - (32%)

  Fly    80 IPYNDW------TLRLTVAIERSHCETFIAFQEQIPEFARYFYHASIYSIWRSLRNRFMFVYTKE 138
            :.|::|      .:|..:||..:...|.::....||:     ..:|.|:|..|.      ||...
 Frog   275 VSYDEWDYDLPARVRDGIAIITTAASTMLSEHNSIPQ-----SKSSCYNIQESR------VYEAH 328

  Fly   139 FEDKKDSYLSGYIFQDQPNILVITSQYLNSSTFEIKTNRFVGPRNFNKNPEPVEFYILQRFDAKG 203
                                  :..:||.:.|||.:...| ....:..:|:.|...:.|
 Frog   329 ----------------------MLKRYLINVTFEGRNLSF-SEDGYQMHPKLVIILLNQ------ 364

  Fly   204 TKATWETQSAMSSKMRNLKGREVVIGIFDYKP---------FMLLDYEKPPLYYDRFMNTTDV-T 258
             :..||...  ..|.|:||.:..|..:|:..|         ..::..|:.|     |:...|| .
 Frog   365 -QRKWERVG--KYKDRSLKMKYYVWPVFELYPNSEEHKDEHLSIVTLEEAP-----FVIVEDVDP 421

  Fly   259 IDGTDIQLMLIFCELYNCTIQVDTSEPYDWG---------------------------DIYL--- 293
            :.||.::      ....|..|:.|....:.|                           |:||
 Frog   422 LSGTCMR------NTVPCRKQIRTENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTN 480

  Fly   294 -------NASGYGLVGMILDRRNDYGVGGMYLWYEAYEYMDMTHFLGRSGVTCLVPAPNRLISWT 351
                   |.:..|::|.::.:|....||.:.:..|..|.:|.:.....:|::.:|...|..:|.:
 Frog   481 GKHGKKINGTWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPS 545

  Fly   352 LLLRPFQFVLWMCVMLCLLLESLA----------LGITRRWEHSSVAAGNS-------WISSLRF 399
            ..|.||...:|:.:.:.||:.|..          :|..|.........|.|       |   |.:
 Frog   546 AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIW---LLW 607

  Fly   400 GCISTLKLFVNQSTNYVTSSYALRTVLVASY-MIDIILTTVYSGGLAAILTLPTLEEAADSRQRL 463
            |      |..|.|............::|:.: ...:|....|:..|||.:   ..||..|....|
 Frog   608 G------LVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFM---IQEEYVDQVSGL 663

  Fly   464 FDHKL--------------IWTGTSQ-----------AWITTIDERSADPVLL----GLMEHYRV 499
            .|.|.              :..|:::           :::...::||....||    |.::.: :
 Frog   664 SDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKTGKLDAF-I 727

  Fly   500 YDANLISAFSHTEQ--------MGFVVERLQFGHLGNTELIENDA--LKRLKLMVDDIYFAFTVA 554
            |||.:::..:..::        .|.|     |...|....|:.|:  .:::.|.:..::....:.
 Frog   728 YDAAVLNYMAGRDEGCKLVTIGSGKV-----FATTGYGIAIQKDSGWKRQVDLAILQLFGDGEME 787

  Fly   555 FVPRLWPHLNAYNDFILAWHSSGFDKFWEWKIAAEYMNAHRQNRIVASEKTNLDIGPVKLGIDNF 619
            .:..||.....:|:                           :|.:::|:          |.|||.
 Frog   788 ELEALWLTGICHNE---------------------------KNEVMSSQ----------LDIDNM 815

  Fly   620 IGLILLWCFGMICSLLTFLGE---LWR 643
            .|:..:....|..||:||:.|   .|:
 Frog   816 AGVFYMLAAAMALSLITFIMEHLFFWQ 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir76a	NP_001097647.3	None
grin2b	XP_017948700.2	PBP1_iGluR_NMDA_NR2	28..383	CDD:380601	29/150 (19%)
		PBP2_iGluR_NMDA_Nr2	400..800	CDD:270436	74/428 (17%)
		NMDAR2_C	837..1449	CDD:402274	1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910