Protein Alignment SREBP and RTG3

DIOPT Version :9

• Sequence 1: NP_001262064.1
• Gene: SREBP / 40155
• FlyBaseID: FBgn0261283
• Length: 1113
• Species: Drosophila melanogaster
• Sequence 2: NP_009447.1
• Gene: RTG3 / 852171
• SGDID: S000000199
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 511
• Identity: 106/511 - (20%)
• Similarity: 175/511 - (34%)
• Gaps: 200/511 - (39%)

  Fly    13 LDESMDLFKAEDVFEPFDADLHSDMLDIILNDMDLAPTQMYNMLLDEPRTHTQQTQSVDQQPQSV 77
            |||.|:..|           :..:.||..|    :.||..:|   |:.:.|.......:...|..
Yeast    15 LDELMNQTK-----------VLQETLDFSL----VTPTPHHN---DDYKIHGSAYPGGETPAQQH 61

  Fly    78 EQQPHVKSEHSSPVH------------------IKEELHQQQQ---------------------- 102
            |:..::.:.:|:..:                  |.||...|..
Yeast    62 EKLSYINTHNSNDNNNLMGSQARSNSQTPTASTIYEEAESQSSYLDDMFRTSQGGRPVTQNSISS 126

  Fly   103 --QSPL-----LVYKPDPLIATSYNCPQQQPTGLLKAAQPTATIHHMDAQRMPPNTAVYPPSLGS 160
              |.||     :.|  |..:..:.|.|.||..| |||..|    |....|.            |:
Yeast   127 IGQGPLRSSYSMAY--DSPVDRAMNTPLQQQEG-LKAELP----HDFLFQH------------GT 172

  Fly   161 SFVYQSMSPPTSPVESANQNVNVMQPVAATPAPASAPLPQQSYPQPFITYNSKAGMTSDEAMYFL 225
            .....:::...|...|::.|.::|.|              .:|...| :||.::
Yeast   173 DDTMYNLTDDLSSSLSSSINSDMMTP--------------NTYSSSF-SYNPQS----------- 211

  Fly   226 LQPTVASPTPSPPVAPPPTS--TGSRAS-----------KVRVAPLAPSPAAMEVQGKVPINRV- 276
            |.|...|.|.||.|..|.:|  .||..|           :.|...::.:.......|.||  ::
Yeast   212 LGPASVSSTYSPKVRSPSSSFRAGSFLSSSFRHGSINTPRTRHTSISSNMTENIGPGSVP--KIL 274

  Fly   277 -----QPKVKEVKRSAHNAIERRYRTSINDKINELKNLV---------VGEQAKLNKSAVLRKSI 327
                 ..|::. ||..|||:|||.|..|..||.||..||         :|:|.|.||..:|.:::
Yeast   275 GGLTSDEKLRR-KREFHNAVERRRRELIKQKIKELGQLVPPSLLNYDDLGKQIKPNKGIILDRTV 338

  Fly   328 DKIRDLQRQNHDLKAELQRLQ----RELMARDGSKVKDLLQLGTRPGRASKKRRESSQTFTTDAG 388
            :.::.|        ||:..:|    :.|:|    |:|:|            :.::||..
Yeast   339 EYLQYL--------AEILEIQARKKKALLA----KIKEL------------EEKKSSVA------ 373

  Fly   389 LTPPRSDESDPSLSPMHSDISLPPSPYGGSTASCSSGSSSSNEEPLV----VPSSM 440
                       :|||..::          ..||....:|.::||.::    ||:::
Yeast   374 -----------ALSPFTNN----------HHASSGQNNSENSEERIIDIRSVPNAL 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SREBP	NP_001262064.1	HLH	281..338	CDD:238036	23/65 (35%)
		OmpH	<289..>364	CDD:281871	28/87 (32%)
RTG3	NP_009447.1	bHLHzip_USF_MITF	289..349	CDD:381393	23/67 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1708
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030