| Sequence 1: | NP_001262064.1 | Gene: | SREBP / 40155 | FlyBaseID: | FBgn0261283 | Length: | 1113 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001263636.1 | Gene: | Srebf1 / 78968 | RGDID: | 69423 | Length: | 1134 | Species: | Rattus norvegicus |
| Alignment Length: | 1247 | Identity: | 381/1247 - (30%) |
|---|---|---|---|
| Similarity: | 529/1247 - (42%) | Gaps: | 275/1247 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 10 DAPLDESMDLFKAEDVFEPFDADLHSDMLDI--ILNDMD-------------------------- 46
Fly 47 ------LAPTQMYNML---LDEPRTHTQQTQSVDQQPQSVEQQPHVKSEHSSPVHIKEELHQQQQ 102
Fly 103 QSPLLVYKPDPLIATSYNCPQQQPTGLLKAAQPTATIHHMDAQ-------------RMPPNTAVY 154
Fly 155 PPS--LGSSFVYQSMSPPTSPVESANQNVNVMQPVAATPAPASAPLPQQSYPQPFITYNSKAGMT 217
Fly 218 SDEAMYFLLQPTVASPTPSPPVAPPP--------------TSTGSRASKVRVAPLAPSPAAME-- 266
Fly 267 ----VQG--------------KVPINRVQPKVKEV--------KRSAHNAIERRYRTSINDKINE 305
Fly 306 LKNLVVGEQAKLNKSAVLRKSIDKIRDLQRQNHDLKAELQRLQRELMARDGSKVKDLLQL----G 366
Fly 367 TRPGRASKKRRESSQTFTTDAGLTPPRSDESDPSLSPMHSDISLPPSPYGGSTASCSSGSSSSNE 431
Fly 432 EPLV---------VPSSMRGMATHSRLGLCMFMFAILAVNPFKTFLQRGHYDSNDDLG--DMSGQ 485
Fly 486 RRILSYDVEGEGFAVWQQSSWIWLLNFTLMLGCLVKLLVYGDPQLDAQTDA---YCQHRQRADFY 547
Fly 548 FSQGQSSQAYAGYLNCLHMFGLSLPASRLECYLQTTWQFLRFLFHRLWLGRVLSRRSGGLFSNAA 612
Fly 613 SRKQALASARELALLFNRLNQLQLTGNGSRGDMNGIMMALFASNMAEVAHNLLTPRETICIHVMT 677
Fly 678 ALRMKRSAPKWLQQLFARYYMSRARQECGLTRATEQTQELRWAFTAYGYRY-----CATHVFTYD 737
Fly 738 LSDSGEQDGFFTRLRNPCDPAAHVIKQYREHLLFKAIQCLVGAGHKSGGLPTSSVSGEAEQLQQQ 802
Fly 803 QHSGTIVSNVLKYTSLLK---------------DTLWADEDERDTNVVWWADVLETAVHWLLGED 852
Fly 853 TLAEQLYGRIKQMPTQLQQCGENDHLPK-ALHAVLRAKMILLKNNGNALDKSLKQLVNILCDESS 916
Fly 917 VELQECLTVNRITDAKGIKLLFQLLTCDWLLETRTALWELEHMNMEDDGFY------QVPGEVLE 975
Fly 976 KFQTDLNSLRNIVENIPNAQSRIYLYEAVCRLMAGASPCPTQQLLDRSLRSRNAHSSIFCGSKDR 1040
Fly 1041 RQQNFVGGE----------RERASAMYVACKYLPPALLSSPGERAGMLAEAAKTLEKVGDKRKLK 1095
Fly 1096 ECYQLMKSLGNG 1107 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SREBP | NP_001262064.1 | HLH | 281..338 | CDD:238036 | 42/64 (66%) |
| OmpH | <289..>364 | CDD:281871 | 46/74 (62%) | ||
| Srebf1 | NP_001263636.1 | Transcriptional activation (acidic). /evidence=ECO:0000250|UniProtKB:P36956 | 1..60 | 11/57 (19%) | |
| 9aaTAD. /evidence=ECO:0000250|UniProtKB:P36956 | 27..35 | 2/7 (29%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 46..102 | 4/55 (7%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 116..221 | 36/156 (23%) | |||
| Interaction with LMNA. /evidence=ECO:0000250|UniProtKB:Q9WTN3 | 227..487 | 102/277 (37%) | |||
| HLH | 315..372 | CDD:238036 | 41/56 (73%) | ||
| Leucine-zipper | 367..388 | 9/26 (35%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 415..468 | 22/64 (34%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 335 | 1.000 | Domainoid score | I1088 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2588 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H3079 | |
| Inparanoid | 1 | 1.050 | 419 | 1.000 | Inparanoid score | I1742 |
| OMA | 1 | 1.010 | - | - | QHG52391 | |
| OrthoDB | 1 | 1.010 | - | - | D167699at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001476 | |
| OrthoInspector | 1 | 1.000 | - | - | otm45443 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104643 | |
| Panther | 1 | 1.100 | - | - | O | PTHR46062 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X2374 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 15 | 14.840 | |||||