Protein Alignment SREBP and USF2

DIOPT Version :9

• Sequence 1: NP_001262064.1
• Gene: SREBP / 40155
• FlyBaseID: FBgn0261283
• Length: 1113
• Species: Drosophila melanogaster
• Sequence 2: XP_024307452.1
• Gene: USF2 / 7392
• HGNCID: 12594
• Length: 397
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 55/259 - (21%)
• Similarity: 84/259 - (32%)
• Gaps: 95/259 - (36%)

  Fly   186 PVAAT--PAPASAPLPQQSYPQPFITYNSKAG-MTSDEAMYFLLQPTVASPTPSPPVAPPPTS-- 245
            |.||:  |.|| ||.|......||....|.|. ..|.||.:.....:....|.:..|.....|
Human   128 PAAASVPPGPA-APFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQ 191

  Fly   246 ----------------TGS-RASKVRVAPLAPSPAAMEVQGKVPINRVQPKVKEVKRSAHNAIER 293
                            ||: |....|..|.:|.           |:..:....|.:|:.||.:||
Human   192 AGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPK-----------IDGTRTPRDERRRAQHNEVER 245

  Fly   294 RYRTSINDKINELKNLV------------------------------------------------ 310
            |.|..||:.|.:|..::
Human   246 RRRDKINNWIVQLSKIIPDCNADNSKTGAVSTPDPQCLRWSRPPTLACRKSNSHGARESSLGWRP 310

  Fly   311 --------VGEQAKLNKSAVLRKSIDKIRDLQRQNHDLK---AELQRLQ--RELMARDGSKVKD 361
                    .|..|..:|..:|.|:.|.||:|::.|..::   .|.:|||  .||:.:...::|:
Human   311 VGGACPKAPGPLAPQSKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKN 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SREBP	NP_001262064.1	HLH	281..338	CDD:238036	21/112 (19%)
		OmpH	<289..>364	CDD:281871	26/134 (19%)
USF2	XP_024307452.1	HLH	233..346	CDD:238036	21/112 (19%)
		ZapB	341..>385	CDD:310531	9/34 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1708
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940