Protein Alignment SREBP and tfe3b

DIOPT Version :9

• Sequence 1: NP_001262064.1
• Gene: SREBP / 40155
• FlyBaseID: FBgn0261283
• Length: 1113
• Species: Drosophila melanogaster
• Sequence 2: NP_001038531.1
• Gene: tfe3b / 564996
• ZFINID: ZDB-GENE-010919-3
• Length: 451
• Species: Danio rerio
• Alignment Length: 472
• Identity: 98/472 - (20%)
• Similarity: 155/472 - (32%)
• Gaps: 169/472 - (35%)

  Fly    94 KEELHQQQQQSPLLVYKP---DPLIATSY------NCPQQQPTGLLKA----AQPTATIHHMDAQ 145
            ::|..:.|||:.:...:|   .|.|:.|.      ..|.|.|..:||.    ..|| ..|...||
Zfish    18 EQERREAQQQASVAQLRPADTTPAISVSLPPMAARPPPAQVPVEVLKVQTHLENPT-KYHIQQAQ 81

  Fly   146 RM----------------------PPNTAVYPPSLGSSFVYQSMSPPTSPVESANQNVN------ 182
            |.                      |...:...|.:|.|    :.|.|.||:...|...|
Zfish    82 RQQVKEYLSTTLGNKVATQTLGVSPVPHSASAPEMGPS----ASSAPNSPMAHLNLGSNKEEMDD 142

  Fly   183 VMQPVAATPA----------PASAPLPQQSYPQPFITYNSKAGMTSDEAMYFLLQPTVASPTPSP 237
            |:..:.:..:          .:...||..........||| .|||:         ||:......|
Zfish   143 VIDDIISLESSFNDDILSLIDSGLQLPNTLPGNLLDVYNS-PGMTT---------PTITVSNSCP 197

  Fly   238 PVAPPPTSTGSRASKVRVAPLAPSPAAMEVQGKVPINRVQPK--VKE-VKRSAHNAIERRYRTSI 299
            ...|                    ....|..|.|.:...:.:  :|| .|:..||.||||.|.:|
Zfish   198 ADLP--------------------NIKREYTGNVIVIETEARAFMKERQKKDNHNLIERRRRFNI 242

  Fly   300 NDKINELKNLV---VGEQAKLNKSAVLRKSIDKIRDLQRQNHDLKAELQRLQRELMARDGS---K 358
            ||:|.||..|:   ...:.:.||..:|:.|:|.||.||::....| |::..|::|...:.:   :
Zfish   243 NDRIKELGALIPKSTDPEMRWNKGTILKASVDYIRKLQKEQQRAK-EIEMRQKKLEQSNQALILR 306

  Fly   359 VKDL--------LQLGTRPGRASKKRRESSQTFTTDAGL-------------------------- 389
            :::|        |.....||..::.....:|....:|.:
Zfish   307 IQELEIQARHHGLNATVSPGLNTEASFIQNQLLQPNASMQAGVGDGQPQSHLNMDGAMAQTSPSP 371

  Fly   390 ---TPPRSD------------------ESDPSLSPMHSDISL----------------PPSPYGG 417
               .||...                  |.|...|.::.|:.|                |.||  |
Zfish   372 FLSVPPSGSPAAVAVSGPLHLETFSFTELDEHASDLYPDVGLSDILMDDVRGSDVLFSPMSP--G 434

  Fly   418 STASCSSGSSSSNEEPL 434
            ::.:.|.|||.:.|:.|
Zfish   435 ASKTSSQGSSINMEDDL 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SREBP	NP_001262064.1	HLH	281..338	CDD:238036	26/60 (43%)
		OmpH	<289..>364	CDD:281871	27/88 (31%)
tfe3b	NP_001038531.1	MITF_TFEB_C_3_N	4..144	CDD:292573	29/130 (22%)
		HLH	224..284	CDD:238036	25/59 (42%)
		DUF3371	312..450	CDD:288684	21/139 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910