Protein Alignment SREBP and hlh-30

DIOPT Version :9

• Sequence 1: NP_001262064.1
• Gene: SREBP / 40155
• FlyBaseID: FBgn0261283
• Length: 1113
• Species: Drosophila melanogaster
• Sequence 2: NP_001023411.1
• Gene: hlh-30 / 177157
• WormBaseID: WBGene00020930
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 95/427 - (22%)
• Similarity: 146/427 - (34%)
• Gaps: 123/427 - (28%)

  Fly    57 LDEPRTHTQQTQSVDQQPQSVEQQPHVKSEHSSPVHIKEELHQQQQQSPLLVYKPDPLIATS--- 118
            |:.||.         |||...:||                  ||.||:....|..:|..|.:
 Worm    16 LNNPRA---------QQPPGAQQQ------------------QQPQQAQQQFYDDEPYQANASQF 53

  Fly   119 -----YNCPQQQPTG-LLKAAQPTATIHHMDAQRMPPNTAVYPPSLGSSFVYQSMSPPTSPVESA 177
                 .:..|::.|| |:..||     ..|.:...|..:|......|......::|.|.. ::..
 Worm    54 RFGAGKSMEQRRETGNLIPIAQ-----RSMGSTSTPFGSAPTQSYFGGGSSGAALSSPRK-MQQT 112

  Fly   178 NQNV--NVMQPVAATPAPASAPLPQ-QSYPQP------------FITYNSKAGMTSDEAMYFLLQ 227
            :|.:  |:..|..:.|:..|..:.: ...|.|            .:..:...||..|:.|    :
 Worm   113 HQMLFGNIQPPRGSPPSDGSDKIHRFGESPTPGGVGGVFGTELDDLIIDELMGMEDDQRM----R 173

  Fly   228 PTVASP-----TPSPPVAPPPTSTGSRASKVRVAPLAPSPAAME------VQGKVPINR--VQPK 279
            |....|     ..:..:|.|.....|||...........|.||.      |....|.:.  ::..
 Worm   174 PGATRPMTIGGEKTMSMARPIPGASSRAGSGHSGSPITIPNAMSNNFRQVVSSSAPTSSIDIEKM 238

  Fly   280 VKEV---------------------KRSAHNAIERRYRTSINDKINELKNLV---VGEQAKLNKS 320
            :..|                     |:..||.||||.|.:|||:|.||..::   ..|..||||.
 Worm   239 IGAVSNGGGNSGGDNDPEDYYRDRRKKDIHNMIERRRRYNINDRIKELGQMLPKNTSEDMKLNKG 303

  Fly   321 AVLRKSIDKIRDLQRQNHD-LKAELQRLQRELMA-RDGSKVKDLLQLGTRPGRASKKRRESSQTF 383
            .:|:.|.|.||.||:.... :|.:.|:...|..| :...:||:|.::..|.|            .
 Worm   304 TILKASCDYIRVLQKDREQAMKTQQQQKSLESTAHKYADRVKELEEMLARQG------------V 356

  Fly   384 TTDAGLTPP-----------RSDESDPSLSPMHSDIS 409
            .......||           ..|||.|:.:|..|.:|
 Worm   357 QVPPSHLPPIPKVIERPIKQEIDESPPNHTPTGSFVS 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SREBP	NP_001262064.1	HLH	281..338	CDD:238036	27/80 (34%)
		OmpH	<289..>364	CDD:281871	31/79 (39%)
hlh-30	NP_001023411.1	bHLHzip_MITF_like	260..328	CDD:381403	27/67 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1708
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940