Protein Alignment SREBP and mitf

DIOPT Version :9

• Sequence 1: NP_001262064.1
• Gene: SREBP / 40155
• FlyBaseID: FBgn0261283
• Length: 1113
• Species: Drosophila melanogaster
• Sequence 2: NP_001093747.1
• Gene: mitf / 100101790
• XenbaseID: XB-GENE-484962
• Length: 483
• Species: Xenopus tropicalis
• Alignment Length: 468
• Identity: 102/468 - (21%)
• Similarity: 156/468 - (33%)
• Gaps: 153/468 - (32%)

  Fly    35 SDMLDIILNDMDLAPTQMYNMLLDEPRTHTQQTQSVDQQPQSVEQQPHVKSEHSSPVHIKEELHQ 99
            |.|...||....|...||.    .:.|...||.|   |..|.::|:..|  .|:..:::...| .
 Frog    51 SSMTSRILLRQQLMREQMQ----QQERREQQQKQ---QAAQFMQQRAAV--SHTPAINVSSSL-P 105

  Fly   100 QQQQSPLLVYKPDPLI--ATSYNCPQ---QQPTGLLKAAQPTATIHHMDAQRMP----PNTAVYP 155
            ...|.|:.|.|....:  .|.|:..|   ||....|..|:     |...|..:|    |...:.|
 Frog   106 ASPQVPMEVLKVQTHLENPTKYHIQQAQKQQVKQYLTTAK-----HSGQALSLPCPNQPGDHIMP 165

  Fly   156 PSLGSSFVYQSMSPPTSPV------------------------ESANQNVNVMQP--VAATPAPA 194
            |..||       |.|.||:                        .|.|:::.:|.|  ..|...|.
 Frog   166 PGPGS-------SAPNSPMALLTIGSTCEKEMDDVIDDIISLESSYNEDILLMDPSMQMANTLPV 223

  Fly   195 SAPL----PQQSYPQPFITYNSKAGMTSDEAMYFLLQPTVASPTPSPPVAPPPTSTGSRASKVRV 255
            |..:    ..|..|.|.:..::                  :.|...|.:....|.:.:||
 Frog   224 SGNMIDIYGNQGMPPPGLNVSN------------------SCPANLPHIKREFTESEARA----- 265

  Fly   256 APLAPSPAAMEVQGKVPINRVQPKVKEVKRSAHNAIERRYRTSINDKINELKNLVV---GEQAKL 317
                   .|.|.|               |:..||.||||.|.:|||:|.||..|:.   ....:.
 Frog   266 -------LAKERQ---------------KKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRW 308

  Fly   318 NKSAVLRKSIDKIRDLQRQNHDLK------AELQRLQRELMARDGSKVKDLLQLGTRPGRASKKR 376
            ||..:|:.|:|.||.|||:....|      .:|:...|.|:.|    :::|          ..:.
 Frog   309 NKGTILKASVDYIRKLQREQQRSKEVENKQKKLEHANRHLLLR----IQEL----------EMQA 359

  Fly   377 RESSQTFTTDAGL-----------TPPRSDESDPSLSPMHSDISLPPSPYGGSTASCSSGSSSSN 430
            |....:.....||           ..|..|..:..:...|.|:|      |.:|...:.|:
 Frog   360 RAHGLSIMPSTGLCSTDLVNRVIKQEPMLDSCNQEILSNHHDLS------GTTTLDLTDGT---- 414

  Fly   431 EEPLVVPSSMRGM 443
               :...:::|.|
 Frog   415 ---ITFSNNLRNM 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SREBP	NP_001262064.1	HLH	281..338	CDD:238036	25/59 (42%)
		OmpH	<289..>364	CDD:281871	29/83 (35%)
mitf	NP_001093747.1	MITF_TFEB_C_3_N	56..194	CDD:318217	38/159 (24%)
		HLH	269..329	CDD:238036	27/74 (36%)
		DUF3371	357..480	CDD:314681	13/81 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910