Protein Alignment CG42637 and si:dkey-37g12.1

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_073809346.1
• Gene: si:dkey-37g12.1 / 796669
• ZFINID: ZDB-GENE-090312-145
• Length: 1067
• Species: Danio rerio
• Alignment Length: 1174
• Identity: 402/1174 - (34%)
• Similarity: 587/1174 - (50%)
• Gaps: 180/1174 - (15%)

  Fly     7 NLLLLLSVAVRDCSNHRTVLTVGYLTALTGDLKTRQGLAISGALTMALDEVNKDPNLLPNVYLDL 71
            ::|||:::.........|:|    ::.....:....|...:||| :|:..||..|.||...:||.
Zfish     6 SMLLLMALVHVSLGTRFTLL----ISMPNTSIPFSSGRIGAGAL-IAISSVNSSPELLRGHHLDY 65

  Fly    72 RW-----NDTKGDTVLAT-------KAITEMICDGIATIFGPEGPCYVEAIVSQSRNIPMISYKC 124
            .:     ||.:|...:|.       .|.....|..:         |.|.|.::...||.:||..|
Zfish    66 HYVDDECNDLRGPGKIAALYNRHKYSAFIGPSCSNV---------CAVTAKLAAFWNIAVISPVC 121

  Fly   125 AEYR---ASAIPTFARTEPPDTQVVKSLLALLRYYAWNKFSILYE--DVWSPVADLLKDQATKRN 184
            |:.:   ..|.||..|...|.|::....:.:.:.:.|....|:|:  ..|:...:.:|.||...|
Zfish   122 ADQQFLDKKAYPTLTRVFGPFTKLGAFFVEICKQFGWQHIGIIYDGKPTWAIPVEGIKYQAEHNN 186

  Fly   185 MTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLF 249
            :|:...|..        ...|....:..|.:::.......||.|.......:...:......||
Zfish   187 ITVAKYQDI--------HSSLSQGSTSNWSRVLNEMAQVARIIVISAHGKVVRSLLIEAHKKGL- 242

  Fly   250 ARGEYMVIFVDMMVYSEREAEKYLRRVDQITFMS-NCHSTENFNQMARS-----LLVVASTPPTK 308
            ..|::  :|.....|.::           :.|.| :....::::.||:.     ..:....|..|
Zfish   243 TNGDF--VFFCFEPYKQK-----------VLFGSFDWEQGDSYDSMAKQAYQALFFLSLYKPSDK 294

  Fly   309 DYIQFTKQVQKYSSKPPFNLEIPRLFVESNF----SKFISIYAAYLYDSVKLYAWAVDKMLREET 369
            .|..|::.|            |.|..::..:    ::.:|:.||..:|:|.|||.|:::.|
Zfish   295 RYQAFSENV------------ISRSKIDFGYTYAQTEKVSVLAAIAHDTVWLYAHALNETL---- 343

  Fly   370 RVLTDDVIFEVASNGT----RVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNS 430
                       |.||.    ..:...:.|||...|.|. :.||..||.|     |.|...:...|
Zfish   344 -----------AENGNPYDGLAVTRRMWNRTIKGIQGD-VTIDASGDRE-----LNYMMKQIRGS 391

  Fly   431 NNMPCNYHMVPVAYFHQGEEHPEYKLING-SIDWPSG-GEKPADEPMCGFANELCKKDDTHYTST 493
            ||. |   .|...||      ..||.:.| .|.||.| ...|.|.|.|||..|||...:..:
Zfish   392 NNQ-C---QVVANYF------GTYKAVKGVQILWPGGLTSPPKDSPDCGFRGELCINLERKF--- 443

  Fly   494 VAAVVLGVL--LFCSGVITMSI-YRKWKIELEIEGLLWKIDPNEI------------KGYSGNEI 543
              .:.||::  |..:|.:.:.: |||:|:..|...:||.|:.|::            |.:....:
Zfish   444 --LIALGIIAGLMAAGTLAICVLYRKYKLPEEASKMLWTINANDVIMMEHHSSTVPEKSHRSKPL 506

  Fly   544 VSSPSKVSLMSAQSYGSRWTNQFVTSTGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHD 608
            .:|...: :.|.|...|      ...|...:|.:..:..:.. |...::.|::.|::..|:|.|.
Zfish   507 QASLESI-ICSMQDKPS------AHRTAVYKGTICSVSFVNL-RSTHLNSELLAELKQFRDLTHY 563

  Fly   609 NINSFIGASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYH 673
            |:..||||::|.::..::|:||.||||.||::||.||||..|..||:.|::|||.|:|:|.|.||
Zfish   564 NLCKFIGAALETSQPFILTEYCPKGSLQDILQNESIKLDWTFKFSLMLDIVKGMDYLHHSPLQYH 628

  Fly   674 GNLKSSNCVVTSRWMLQVTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHI--HGSQKGD 736
            |:|.||:|||.||::|:||||||:.:|:....:|.|. ..:...|||||||||..|  :|:||||
Zfish   629 GHLSSSSCVVDSRFVLKVTDFGLNSVRRLDTEQSPGS-DPWTALLWRAPELLRQSIPANGTQKGD 692

  Fly   737 VYAFAIIMYEIFSRKGPF--GQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLAC 799
            ||:||||..|:..|:|||  ...:|.|:|||:.|:   ..|..|.||    .|:...|.:.:.:.
Zfish   693 VYSFAIIAQEVVYRRGPFYIPNSHFSPREIVERVR---AGGCSPSRP----YIDRAECVEELESL 750

  Fly   800 IRDCWAEDPEERPEFSVIRNRLKK-MRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKM 863
            :..||.|.|.|||:||.||..:|| ...|.::||:|.::..||:||.|||:||:|||..|.|||.
Zfish   751 VVSCWRETPAERPDFSYIRTAIKKNSPHGVSENILDDLLSRMEQYACNLEEIVSERTAELQEEKK 815

  Fly   864 KTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVF 928
            :.|.||.:|||:|||.:|..|:.|...:||.||||||||.|||||||..||:||||.||||||.|
Zfish   816 RAEGLLTQMLPRSVASQLIAGKTVRAETYDCVTIYFSDIEGFTAMSASLTPMQVVNVLNDLYTYF 880

  Fly   929 DRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRI 993
            |.||..::|||||||||||||||||||:|||.||.|||.|:|.::..::.....|.|.:.|::||
Zfish   881 DNIIDYHNVYKVETIGDAYMVVSGLPIRNGDDHAKEIARMSLAIVQGLRSFHSPHVPEQQLRVRI 945

  Fly   994 GMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGL 1058
            |:|:||.|||||||.|||||||||||||||||||.|..||||:|:..|..||.. ..:..|.||.
Zfish   946 GVHSGPCVAGVVGLKMPRYCLFGDTVNTASRMESYGLPLKIHVSSSTKSLLDTF-RNFRCELRGD 1009

  Fly  1059 VNMKGKGDVVTWWLTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQP------SIQAMH 1117
            :::|                ::...|......|.||...|  .|:|.|  :.|      |:.|:.
Zfish  1010 IHIK----------------SLPSSLPRCSPRPAPLALHP--PPELLP--QLPFQDGGGSVTAVS 1054

  Fly  1118 FCGT 1121
            |..|
Zfish  1055 FVDT 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593	95/449 (21%)
		PK_GC-A_B	543..827	CDD:270944	116/288 (40%)
		HNOBA	<833..881	CDD:462234	26/47 (55%)
		CYCc	860..1052	CDD:214485	121/191 (63%)
si:dkey-37g12.1	XP_073809346.1	None