DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42637 and Gucy1a2

DIOPT Version :10

Sequence 1:NP_524165.2 Gene:CG42637 / 40153 FlyBaseID:FBgn0261360 Length:1525 Species:Drosophila melanogaster
Sequence 2:NP_076446.1 Gene:Gucy1a2 / 66012 RGDID:621655 Length:730 Species:Rattus norvegicus


Alignment Length:351 Identity:122/351 - (34%)
Similarity:179/351 - (50%) Gaps:65/351 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   743 IMYEIFSRKGPFGQINFEPKEIVDYV-----KKL------PLKGEDPFR---PEV----ESIIEA 789
            |....|.|..|| .:.|:|..:|..:     |:|      .||.||.|.   |:|    :.::..
  Rat   316 ISINTFCRTFPF-HLMFDPNMVVLQLGEGLRKQLRCDNHKVLKFEDCFEIVSPKVNATFDRVLLR 379

  Fly   790 ESCPDYVLACIRDCWAEDPEER-----------PEFSVIR-------NRLKKMRG---------- 826
            .|.| :|:....:....|.|::           ||.:.|.       ::|.::.|          
  Rat   380 LSTP-FVIRTKPEASGTDNEDKVMEIKGQMIHVPESNAILFLGSPCVDKLDELIGRGLHLSDIPI 443

  Fly   827 ----------GKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKL 881
                      |:.....|.:.:.|:|....||    :..:.|.|||.||.|||:.:.|..||::|
  Rat   444 HDATRDVILVGEQAKAQDGLKKRMDKLKATLE----KTHQALEEEKKKTVDLLYSIFPGDVAQQL 504

  Fly   882 TMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDA 946
            ...|.|:...:|.||:.|||||||||:.|:.||:||::.||:|||.||......|:|||||||||
  Rat   505 WQRQQVQARKFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGFLDIYKVETIGDA 569

  Fly   947 YMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPR 1011
            |.|.|||..|: ..||..||.|||:::...::  :.......:::|||:|:|.|:|||||:.|||
  Rat   570 YCVASGLHRKS-LCHAKPIALMALKMMELSEE--VLTPDGRPIQMRIGIHSGSVLAGVVGVRMPR 631

  Fly  1012 YCLFGDTVNTASRMESNGEALKIHIS 1037
            |||||:.|..||:.||.....:|:||
  Rat   632 YCLFGNNVTLASKFESGSHPRRINIS 657

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42637NP_524165.2 PBP1_SAP_GC-like 26..445 CDD:380593
PK_GC-A_B 543..827 CDD:270944 27/139 (19%)
HNOBA <833..881 CDD:462234 17/47 (36%)
CYCc 860..1052 CDD:214485 88/178 (49%)
Gucy1a2NP_076446.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53
HNOB <157..268 CDD:462233
HNOBA 314..501 CDD:462234 43/190 (23%)
Guanylate_cyc 512..696 CDD:425528 74/149 (50%)
Blue background indicates that the domain is not in the aligned region.

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