DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG42637 and adcy7

DIOPT Version :10

Sequence 1:NP_524165.2 Gene:CG42637 / 40153 FlyBaseID:FBgn0261360 Length:1525 Species:Drosophila melanogaster
Sequence 2:XP_021333246.1 Gene:adcy7 / 568726 ZFINID:ZDB-GENE-040713-1 Length:1119 Species:Danio rerio


Alignment Length:454 Identity:120/454 - (26%)
Similarity:188/454 - (41%) Gaps:132/454 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   689 LQVTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHIHGSQKGDVYAFAIIMYEIFSRKGP 753
            |:.|| .|.:|.|  :|.|..:..  |::|...|.|:.|.|          .|:|...:|.|   
Zfish   715 LKKTD-NLCDLLQ--QNSSFADSA--RDELQYLPYLVYNCI----------LALIACGVFLR--- 761

  Fly   754 FGQINFEPK-------EIVDYVKKLPLKGEDPFRPEVESIIEA-ESCPDYVLAC---------IR 801
               ::||.|       .:|.|.  :.|..::........::.. .||.|.::.|         |.
Zfish   762 ---VSFELKLAFLLIVSLVSYT--IILYSQENLFSNYNCLLYTNHSCGDSLMVCKAGLMKHPKIM 821

  Fly   802 DC------------WAEDPEE--RPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVT 852
            .|            .:...|.  |.:|.:           |.||:.|:  |.:|           
Zfish   822 SCIYITLFLFTMLLISRQNEYCCRQDFLL-----------KNKNLADK--EEVE----------- 862

  Fly   853 ERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEP--------------------VSYDLVTI 897
                 |||...:.  ||..:||..|| .|.:|:..:.                    .|||.|.:
Zfish   863 -----LCENLNRL--LLENVLPAHVA-ALFVGENKKNEVGLLSAISLLNRKYKDLYYKSYDCVCV 919

  Fly   898 YFSDIVGF----TAMSAESTPLQVVNFLNDLYTVFDRII---RGYDVYKVETIGDAYMVVSGL-- 953
            .|:.:..|    |........|:.:..||::...||.::   :...|.|::|||..||..:||  
Zfish   920 MFASVPDFKEFYTECDINKEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAAAGLSG 984

  Fly   954 --PIKNGDR-----HAGEIASMALEL---LHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLT 1008
              ...|.||     ..|.:...|:.|   |..:.:|..     .|.:||:|::.|||:|||:|..
Zfish   985 PPEQSNQDRERQNAQIGNMVEFAIALIGKLDGINRHSF-----NTFRLRVGINHGPVIAGVIGAR 1044

  Fly  1009 MPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWL 1072
            .|:|.::|:|||.||||||.||..||.::.:..:.|..|  ||..|.|||:|:||||::.|:::
Zfish  1045 KPQYDIWGNTVNVASRMESTGELGKIQVTEETSIVLQNL--GYSCECRGLINVKGKGELKTFFV 1106

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42637NP_524165.2 PBP1_SAP_GC-like 26..445 CDD:380593
PK_GC-A_B 543..827 CDD:270944 33/168 (20%)
HNOBA <833..881 CDD:462234 12/47 (26%)
CYCc 860..1052 CDD:214485 68/230 (30%)
adcy7XP_021333246.1 AC_N <129..248 CDD:318454
Guanylate_cyc 272..455 CDD:425528
Adcy_cons_dom 487..615 CDD:461877
Guanylate_cyc 909..1106 CDD:425528 70/203 (34%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.