Protein Alignment CG42637 and si:ch211-132f19.7

DIOPT Version :9

• Sequence 1: NP_001007096.1
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_688903.4
• Gene: si:ch211-132f19.7 / 560410
• ZFINID: ZDB-GENE-130530-619
• Length: 1183
• Species: Danio rerio
• Alignment Length: 1081
• Identity: 210/1081 - (19%)
• Similarity: 375/1081 - (34%)
• Gaps: 341/1081 - (31%)

  Fly   226 IYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRRVDQITFMSNCHSTEN 290
            |:::|..|..:||.........|.|.|  .:|.|.::......:..|||.....:::|
Zfish   170 IFIYLALAPEMVDSQHGWLAGLLMALG--AIICVLVLTCKGLMSPDYLRYAGLASWLS------- 225

  Fly   291 FNQMARSL--LVVASTPPTKDYIQFTKQVQKYSSKP-PFNLEIPRLFVESNFSKFISIYAAYLYD 352
              |..::|  ||.........|:.|| ....|:..| |....|...|:.:....|:..:..|...
Zfish   226 --QTVQALGGLVYGLETDQSWYVLFT-LFAIYTLLPLPLLWSICMGFLTAALHLFVDTFKNYNDT 287

  Fly   353 SV--KLYA----------------WAVDKMLRE---ETRVLTDDVIFEVASNGTRVIDTIIK--- 393
            ::  ||.|                :..|:..|:   |||               |.|:..:|
Zfish   288 AIVRKLLAKGLLYMGMNTAGLFIHYLSDRAQRQAFLETR---------------RCIEGRVKMER 337

  Fly   394 -----NRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEE--- 450
                 .|..|||....|.::..||.......|            :|..:|.   .||||.::
Zfish   338 ENQRQERLVMSILPRFIAMEMIGDMTALDDEL------------LPQQFHK---TYFHQYKDVSI 387

  Fly   451 --------------HPEYKLINGSIDWPSGGEKPADEPMC------------------------- 476
                          .|..:|:....:.....::.|:|..|
Zfish   388 LFADIKGFTSLSMTMPAQELVRTLNELFGRFDRLAEENHCMRIKILGDCYYCVSGVPEPQTAHAR 452

  Fly   477 -----GFA---------NELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKWKIE------- 520
                 |.|         .||.:..|........:|:.|||    |:      :||:.:
Zfish   453 CCVEMGLAMINTIRYVRKELKRDMDMRIGIHSGSVLCGVL----GL------QKWQFDVWSWDVD 507

  Fly   521 ----LEIEGLLWKI--------------DPNEIKGYSGNEIV-----------------SSPSKV 550
                ||..|:..:|              :..|.:|:..||.:                 ..|.||
Zfish   508 VANMLEAGGIPGRIHISRATLDCLEGVYETEEGRGHERNEFLRKHKIDTFLIRHTPQDDKEPPKV 572

  Fly   551 SLMSAQSYGSRWTNQ------------FVTSTGRLRGAVVRIKELKFPR---KRDISREIMK--E 598
            ...|...  :.|:.:            ..|.|   .|::|.:.....|.   .|:|::.|.:  |
Zfish   573 RRTSKDE--TTWSAELPFDNIIGMNCILATFT---NGSLVHLPNQITPHCAGSREINKRIKQAIE 632

  Fly   599 MRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMI 663
            :|....:|.::|..|         .|:..|...:|....:       .|::|.::|....:. ::
Zfish   633 VRSSERMRKEHITPF---------TLVFKDTHIEGKFSQM-------RDEMFKSNLACSFLL-LL 680

  Fly   664 YIHNSQLVYHGNLKSSNCVVTSRWMLQVTDF-------GLHELRQCAENESIGEHQHYRNQLWRA 721
            :|..:|.:          :.:.::...:..|       .|..|...||            :..|:
Zfish   681 FIMAAQAL----------IPSPQFFPMIIQFLVFLFVYMLVLLVTLAE------------EFKRS 723

  Fly   722 PELLRN---HIHGSQK--------GDVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKG 775
            |..|::   .||.::.        .....|.:....||...|.|.:.....|. .::.|:.|:
Zfish   724 PPYLQHLCCWIHETKSIRNLLTLTAIAINFGVASCNIFWCNGTFEETEKSNKN-SEHGKQWPV-- 785

  Fly   776 EDPFRPE---VESIIEAESCPDYV-LACIRDCWAEDPEERPEFSVI------------------- 817
            .....||   :..::...:|..:: |:|:.           :.:|:
Zfish   786 NICTHPEFFVLSGVVAMVTCAVFLRLSCLL-----------KLAVLTLVIAVYTYLIEVAFHVLF 839

  Fly   818 -----RNRLKKMRGGKTKNIMDQMMEMMEKYA--NNLEDIVTERTRLLCE-------EKMK---- 864
                 .:::::.:..:.|.|...:|.|.....  |:.:...|.|...|..       |.||
Zfish   840 IRQHQNSQIQRSQYLRRKGISVLLMAMFVVVVLYNSRQLETTSRLDFLWRLQARQEVEDMKELRE 904

  Fly   865 -TEDLLHRMLPQSVA----EKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAES----TPLQVVNF 920
             .|.||:.:||..||    |:....:.:...||:.|.:.|:.|.||:....:.    ..::.:..
Zfish   905 HNECLLYNILPAHVARHFLERDRNNEDLFSESYERVGVMFASIPGFSDYYEKKELIHQDVECLRL 969

  Fly   921 LNDLYTVFDRII-RGY--DVYKVETIGDAYMVVSGLPIKNGD-----RHAGEIASMALELLHAVK 977
            ||::...||.:: ..|  |:.|::|||..||..|||..:..:     .|...:...||.:...:|
Zfish   970 LNEIIADFDELLDEPYFQDIEKIKTIGSCYMAASGLSPEKQECEDEWAHLSTLVLFALAMQETLK 1034

  Fly   978 QHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKL 1042
            :  |..|.:....||:|:..|||||||:|.|.|:|.::|.|||.||||:|.|.:.:|.:......
Zfish  1035 E--INKRTSNDFWLRVGISHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGLSGRIQVPEATSR 1097

  Fly  1043 ALDKLGGGYITEKRGLVNMKG----KGDVVTWWLTGANENA 1079
            .|.:  .|::.:.||.:.:||    :|.|.|::::....|:
Zfish  1098 VLAE--HGFMLQLRGEIYVKGVSERRGAVRTYFVSSREHNS 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365	49/250 (20%)
		ANF_receptor	48..412	CDD:279440	44/217 (20%)
		PK_GC-A_B	543..827	CDD:270944	50/363 (14%)
		HNOBA	<835..881	CDD:285003	17/63 (27%)
		CYCc	860..1052	CDD:214485	66/219 (30%)
		Guanylate_cyc	887..1074	CDD:278633	62/202 (31%)
si:ch211-132f19.7	XP_688903.4	AC_N	<133..375	CDD:292831	48/243 (20%)
		CYCc	338..537	CDD:214485	35/223 (16%)
		Guanylate_cyc	381..559	CDD:278633	26/187 (14%)
		DUF1053	579..667	CDD:283888	18/108 (17%)
		CYCc	903..1103	CDD:214485	62/203 (31%)
		Guanylate_cyc	932..1131	CDD:278633	62/202 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810