DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42637 and adcy1a

DIOPT Version :10

Sequence 1:NP_524165.2 Gene:CG42637 / 40153 FlyBaseID:FBgn0261360 Length:1525 Species:Drosophila melanogaster
Sequence 2:NP_001161821.1 Gene:adcy1a / 557026 ZFINID:ZDB-GENE-070705-302 Length:1114 Species:Danio rerio


Alignment Length:385 Identity:94/385 - (24%)
Similarity:166/385 - (43%) Gaps:90/385 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   828 KTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVS- 891
            :.:|.:.|.::        |||           |..|.|.||..:||::||.:: ....::|.. 
Zfish   238 QARNCIQQRLQ--------LED-----------ENEKQERLLMSLLPRNVAMEM-KEDFLKPPER 282

  Fly   892 ---------YDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAY 947
                     :|.|:|.|:||||||:::::.|..::|..||:|:..||.:.......:::.:||.|
Zfish   283 IFHKIYIQRHDNVSILFADIVGFTSLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCY 347

  Fly   948 MVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRY 1012
            ..||||.....| ||.....|.|:::..:..  :|......|.:|:|:|||.|:.||:||...:|
Zfish   348 YCVSGLTQPKAD-HAHCCVEMGLDMIDTITS--VAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY 409

  Fly  1013 CLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMK----GKGDVVTWWLT 1073
            .::.:.|..|:.||:.|...|:||:   |..|:.|.|.|..|. |..:.:    .|..:.|:::.
Zfish   410 DVWSNDVTLANMMEAGGLPGKVHIT---KATLECLNGDYEVEP-GFGHERHAFLSKHAIETFFIV 470

  Fly  1074 GANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQP-------SIQAMH-------------- 1117
            .::...|...|: :.|              :.|..|..       .:|.||              
Zfish   471 PSHRRKIFPGLI-LSD--------------IKPAKRMEFKTVCYLLVQLMHCRKMFKAEIPFSNV 520

  Fly  1118 -FCGTGSRRQS--TVPRAMDGESTYSLQGSVRESP---------RMVSKRDRDRERPPIN 1165
             .|....:|::  |....:...:::| .|.|:.||         |::..|..:.|...:|
Zfish   521 MTCEDDDKRRALRTASEKLRNRTSFS-AGMVQNSPGTRVNRYIGRLIEARQTESEMADLN 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42637NP_524165.2 PBP1_SAP_GC-like 26..445 CDD:380593
PK_GC-A_B 543..827 CDD:270944
HNOBA <833..881 CDD:462234 13/47 (28%)
CYCc 860..1052 CDD:214485 64/201 (32%)
adcy1aNP_001161821.1 AcyC 114..449 CDD:441717 70/236 (30%)
Guanylate_cyc 287..469 CDD:425528 59/188 (31%)
Adcy_cons_dom 513..602 CDD:461877 12/68 (18%)
Guanylate_cyc 852..1048 CDD:425528
Blue background indicates that the domain is not in the aligned region.

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