DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42637 and adcy1a

DIOPT Version :9

Sequence 1:NP_001007096.1 Gene:CG42637 / 40153 FlyBaseID:FBgn0261360 Length:1525 Species:Drosophila melanogaster
Sequence 2:NP_001161821.1 Gene:adcy1a / 557026 ZFINID:ZDB-GENE-070705-302 Length:1114 Species:Danio rerio


Alignment Length:385 Identity:94/385 - (24%)
Similarity:166/385 - (43%) Gaps:90/385 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   828 KTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVS- 891
            :.:|.:.|.::        |||           |..|.|.||..:||::||.:: ....::|.. 
Zfish   238 QARNCIQQRLQ--------LED-----------ENEKQERLLMSLLPRNVAMEM-KEDFLKPPER 282

  Fly   892 ---------YDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAY 947
                     :|.|:|.|:||||||:::::.|..::|..||:|:..||.:.......:::.:||.|
Zfish   283 IFHKIYIQRHDNVSILFADIVGFTSLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCY 347

  Fly   948 MVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRY 1012
            ..||||.....| ||.....|.|:::..:..  :|......|.:|:|:|||.|:.||:||...:|
Zfish   348 YCVSGLTQPKAD-HAHCCVEMGLDMIDTITS--VAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY 409

  Fly  1013 CLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMK----GKGDVVTWWLT 1073
            .::.:.|..|:.||:.|...|:||:   |..|:.|.|.|..|. |..:.:    .|..:.|:::.
Zfish   410 DVWSNDVTLANMMEAGGLPGKVHIT---KATLECLNGDYEVEP-GFGHERHAFLSKHAIETFFIV 470

  Fly  1074 GANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQP-------SIQAMH-------------- 1117
            .::...|...|: :.|              :.|..|..       .:|.||              
Zfish   471 PSHRRKIFPGLI-LSD--------------IKPAKRMEFKTVCYLLVQLMHCRKMFKAEIPFSNV 520

  Fly  1118 -FCGTGSRRQS--TVPRAMDGESTYSLQGSVRESP---------RMVSKRDRDRERPPIN 1165
             .|....:|::  |....:...:::| .|.|:.||         |::..|..:.|...:|
Zfish   521 MTCEDDDKRRALRTASEKLRNRTSFS-AGMVQNSPGTRVNRYIGRLIEARQTESEMADLN 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42637NP_001007096.1 PBP1_Speract_GC_like 26..445 CDD:107365
ANF_receptor 48..412 CDD:279440
PK_GC-A_B 543..827 CDD:270944
HNOBA <835..881 CDD:285003 13/45 (29%)
CYCc 860..1052 CDD:214485 64/201 (32%)
Guanylate_cyc 887..1074 CDD:278633 60/200 (30%)
adcy1aNP_001161821.1 AC_N <154..285 CDD:292831 15/66 (23%)
CYCc 251..446 CDD:214485 65/212 (31%)
Guanylate_cyc 287..469 CDD:278633 59/188 (31%)
DUF1053 513..601 CDD:283888 12/68 (18%)
CYCc 819..1029 CDD:214485
Guanylate_cyc 852..1048 CDD:278633
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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