Protein Alignment CG42637 and NPR3

DIOPT Version :9

• Sequence 1: NP_001007096.1
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: NP_001191304.1
• Gene: NPR3 / 4883
• HGNCID: 7945
• Length: 541
• Species: Homo sapiens
• Alignment Length: 540
• Identity: 111/540 - (20%)
• Similarity: 207/540 - (38%)
• Gaps: 138/540 - (25%)

  Fly    30 YLTALTGDLKTRQGLAISGALTMALDEVNKD---PNLLPNVYLDLRWNDTKGDTVLATKAITEMI 91
            ||.:||         .:..|:..||..|..:   ..|||.   ..|:.....|:....:|:..::
Human    65 YLFSLT---------RVRPAIEYALRSVEGNGTGRRLLPP---GTRFQVAYEDSDCGNRALFSLV 117

  Fly    92 CDGIATIFGPE-----GP-C-YVEAIVSQSR---NIPMIS---------YKCAEYRASAIPTFAR 137
             |.:|...|.:     || | |..|.|::..   ::||:|         :|.:||     ....|
Human   118 -DRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEY-----SHLTR 176

  Fly   138 TEPPDTQVVKSLLALLRYYAWNKFSILYED---------VWSPVADLLKDQATKRNMTINHKQSF 193
            ..|...::.:.:|||.|::.|::.:::|.|         ....|.::.:::....::     .||
Human   177 VAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSI-----YSF 236

  Fly   194 IDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIF 258
            .:.:....|            .:|:|.....|:.:...:::::...|......|: ..|:|....
Human   237 DETKDLDLE------------DIVRNIQASERVVIMCASSDTIRSIMLVAHRHGM-TSGDYAFFN 288

  Fly   259 VDMMVYSEREAEKYLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTK-DYIQFTKQVQKYSS 322
            :::. .|....:...:|.|:..|.:        .|...||..|......| ::.:|:.:|:....
Human   289 IELF-NSSSYGDGSWKRGDKHDFEA--------KQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVE 344

  Fly   323 KPPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRV 387
            |...|:|           .:::::....:|::.||..|:.::||....          ..:|.::
Human   345 KQGLNME-----------DYVNMFVEGFHDAILLYVLALHEVLRAGYS----------KKDGGKI 388

  Fly   388 IDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYF-HQG--E 449
            |.. ..|||:..|.| ::.||..||..|:|||:|        ..::......|...|| .:|  |
Human   389 IQQ-TWNRTFEGIAG-QVSIDANGDRYGDFSVIA--------MTDVEAGTQEVIGDYFGKEGRFE 443

  Fly   450 EHPEYKLINGSIDWPSGGEK-PADEPMCGFANEL--------CKKDDTHYTSTVAAVVLGVLLFC 505
            ..|..|       :|.|..| ..||      |.:        ||.......|.|..:|:|.||
Human   444 MRPNVK-------YPWGPLKLRIDE------NRIVEHTNSSPCKSSGGLEESAVTGIVVGALL-- 493

  Fly   506 SGVITMSIY---RKWKIELE 522
            ...:.|:.|   :|::|.:|
Human   494 GAGLLMAFYFFRKKYRITIE 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365	86/446 (19%)
		ANF_receptor	48..412	CDD:279440	74/395 (19%)
		PK_GC-A_B	543..827	CDD:270944
		HNOBA	<835..881	CDD:285003
		CYCc	860..1052	CDD:214485
		Guanylate_cyc	887..1074	CDD:278633
NPR3	NP_001191304.1	PBP1_NPR_C_like	54..446	CDD:107381	90/456 (20%)
		ANF_receptor	71..422	CDD:279440	81/417 (19%)
		TM_EphA1	476..507	CDD:214014	8/32 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810