DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42637 and Gycbeta100B

DIOPT Version :9

Sequence 1:	NP_001007096.1	Gene:	CG42637 / 40153	FlyBaseID:	FBgn0261360	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_524603.2	Gene:	Gycbeta100B / 43682	FlyBaseID:	FBgn0013973	Length:	787	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	123/381 - (32%)
Similarity:	189/381 - (49%)	Gaps:	72/381 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   744 MYEIFSRKGPFGQINFEPKEIVDYV-------------------KKLPLKGEDPFRPEVESIIEA 789
            :.|:.....|..|:|||  .|:.::                   :.|.|||:..:.||.:.|
  Fly   370 LIEVVEAIRPHLQLNFE--NILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQMMYIPETDRI--- 429

  Fly   790 ESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKK---------MRGGKTKNIMDQMMEMMEKYAN 845
                      :..|:       |....:.:..||         ....:...::.:..|...|...
  Fly   430 ----------LFQCY-------PSVMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTK 477

  Fly   846 NLE---DIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTA 907
            |||   |.:.:..|.|..||.||:.||:.:||:|||.:|...:.|.|..||.||:.||.||||..
  Fly   478 NLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQ 542

  Fly   908 MSAEST----PLQVVNFLNDLYTVFDRII---RGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEI 965
            ..|.:|    .:::|..||:||||||.:.   |..:||||||:||.||.||||| .:.:.||..:
  Fly   543 YCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLP-DHCEDHAKCM 606

  Fly   966 ASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGE 1030
            |.:||:::...|..::...|   :::.||:|:|.||.||:|..:|||||||:|||..||.|:.|.
  Fly   607 ARVALDMMDMAKNVKMGSNP---VQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGV 668

  Fly  1031 ALKIHISNK-----CKLALDKLGGGYITEKRGLVNMKGKGDVV-TWWLTGANENAI 1080
            ..:|::|.:     | :|::: ...:..|.||.|.||||...: .|:||.|..:.:
  Fly   669 PGRINVSEETYRLLC-MAINQ-DDSFHLEYRGPVIMKGKPTPMDCWFLTRATSSIL 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365
		ANF_receptor	48..412	CDD:279440
		PK_GC-A_B	543..827	CDD:270944	18/110 (16%)
		HNOBA	<835..881	CDD:285003	19/48 (40%)
		CYCc	860..1052	CDD:214485	85/203 (42%)
		Guanylate_cyc	887..1074	CDD:278633	83/199 (42%)
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:285002
		HNOBA	326..516	CDD:285003	37/167 (22%)
		CYCc	496..688	CDD:214485	85/196 (43%)
		Guanylate_cyc	522..714	CDD:278633	82/197 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740