DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42637 and Gyc89Db

DIOPT Version :9

Sequence 1:	NP_001007096.1	Gene:	CG42637 / 40153	FlyBaseID:	FBgn0261360	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	NP_650551.1	Gene:	Gyc89Db / 42002	FlyBaseID:	FBgn0038436	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	104/315 - (33%)
Similarity:	169/315 - (53%)	Gaps:	33/315 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   768 VKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKK--------M 824
            ::.:.|||:..:..:|:|:|..  |...:         |:.:|.....:..|.|..        |
  Fly   373 LRSILLKGQMFYIKDVDSLIFL--CSPLI---------ENLDELHGIGLYLNDLNPHGLSRELVM 426

  Fly   825 RGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEP 889
            .|.:..:.::.|.|..|:.::.||    :...|....|.:.::||:.|:|:.:||::...:....
  Fly   427 AGWQHCSKLEIMFEKEEQRSDELE----KSLELADSWKRQGDELLYSMIPRPIAERMRKSEEHVC 487

  Fly   890 VSYDLVTIYFSDIVGFTAMSAES--TPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSG 952
            .|::.|::.|.:::......:.:  ..:|.|..||.:::..|..|....||||||:|..||.|||
  Fly   488 QSFEEVSVIFIEVMNIYDSGSNNIQDAMQAVTTLNKVFSALDEEIISPFVYKVETVGMVYMAVSG 552

  Fly   953 LPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGD 1017
            .|..| ..||.....:||.::..||.|.:   |.  :.:|:|:::|||||||||:.:||||||||
  Fly   553 APDVN-PLHAEHACDLALRVMKKVKAHAL---PG--VAIRVGINSGPVVAGVVGMKVPRYCLFGD 611

  Fly  1018 TVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWL 1072
            ||||||||||:.:...|.:||...|.:.|:  ||..|.||.|.:||||::.|:||
  Fly   612 TVNTASRMESSSDPWMIQLSNYTALKVQKV--GYKVEARGFVKVKGKGEMETYWL 664

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365
		ANF_receptor	48..412	CDD:279440
		PK_GC-A_B	543..827	CDD:270944	12/66 (18%)
		HNOBA	<835..881	CDD:285003	13/45 (29%)
		CYCc	860..1052	CDD:214485	73/193 (38%)
		Guanylate_cyc	887..1074	CDD:278633	78/188 (41%)
Gyc89Db	NP_650551.1	HNOB	2..161	CDD:400167
		HNOBA	218..479	CDD:400168	26/120 (22%)
		Nucleotidyl_cyc_III	488..665	CDD:416391	78/185 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454044
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740