Protein Alignment CG42637 and ACXC

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: NP_609593.1
• Gene: ACXC / 34689
• FlyBaseID: FBgn0040508
• Length: 1130
• Species: Drosophila melanogaster
• Alignment Length: 1235
• Identity: 243/1235 - (19%)
• Similarity: 404/1235 - (32%)
• Gaps: 469/1235 - (37%)

  Fly   197 RVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDM 261
            |.||.|..|:  ....:||:.....|.|..||..     ::..||.:....|:.: .|..:|.:.
  Fly    37 REKCKELNLE--EEYRYYQVRLMVSNLTIFYVLF-----IILAMSFLTIELLYVQ-HYNAVFFNF 93

  Fly   262 MVYSEREAEKYL-RRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPP 325
            ::   |.....| ..|..|.|.....|...:..:|.|:|.|.....| |.:..:...  |.:..|
  Fly    94 VI---RVVSTILVLTVLSINFCEKFVSRHRWVMIASSVLSVYLVVLT-DIVMISYHF--YKNDWP 152

  Fly   326 FN--------------LEIPRLFVESNFSKFIS-IYAAYLYDSVKLYAWAVDKMLREE--TRVLT 373
            .|              |.||.:...:..:..:| ||.|:...|:...|...|   |:.  ..|::
  Fly   153 LNTSFDVFTLCMIYMFLPIPSIKGAALLASSVSLIYVAFFMHSLTFNAVYTD---RDSFGYDVIS 214

  Fly   374 DDVIFEVASNGTRVI-----DTIIK-----------NRTYM--SITGSKIKIDQYGDSEGNFSVL 420
            .|::..:..|...:.     ||:::           ..|::  ::....|.:|         |:|
  Fly   215 TDILHNLGFNMMGIFFRIMNDTMVRASFLDRHQFIMEETWLRHALLQESILLD---------SIL 270

  Fly   421 ---AYKP------HKWNNSNNMPCNYHMVP--VAYFHQGEEHPEYKLINGSIDWPSGGEKPADEP 474
               ..||      .|...|.|.|..:.|.|  ...|...:.||:..::...:
  Fly   271 PPQIAKPVQEKIKSKITQSENSPDRFQMGPRTTESFMAIQIHPDVSILYADV------------- 322

  Fly   475 MCGFANELCKKDDTHYTST------------------VAA------------------------- 496
                      .:.||.|:|                  :||
  Fly   323 ----------VNYTHLTTTLTVGNLVKVLHDLYGRFDIAASNFKVQRIKFLGDCYYCVAGLTTPD 377

  Fly   497 -------VVLGVLLFC--------------------SGVITMSIYRKWKIELEIEGLLWKID--- 531
                   |.||:.:..                    ||.:...|..:.|::.:|    |..|
  Fly   378 PDHAKCCVSLGISMISNIQEVRAERGLDIDMRIGVHSGSLLAGIIGEAKLQFDI----WGTDVEI 438

  Fly   532 PNEIK-----GY---SGNEI-VSSPSKVSLMS----AQS------------YGSRWTNQFVTSTG 571
            .|.::     ||   ||..: :.:|:..:::|    |||            .|......|:||.|
  Fly   439 ANHLESTGEPGYVHVSGRTLSMLNPADYTILSGTQKAQSDPVLQYIHTYLLTGQVARESFITSIG 503

  Fly   572 RLR-GAVVRIKEL-----KFPRKRDISREIMKEMRLL------------RELR---HDNINSFIG 615
            .:| .:|:.:|.:     ..|.:..::.|..:|.|.:            |..|   |......||
  Fly   504 GVRSSSVLEVKSIDRIRSSRPSQSSMTDEFREEFRNMPVGGINLNSPCCRRTRLDTHKKTQREIG 568

  Fly   616 ASVEPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKG----MIYIHNSQLVYHGNL 676
            .            :||......:..|...:.|.:|.:|::  |..|    :|||   |:|.: |.
  Fly   569 I------------FCAAFKDSSLEWNYLHQPDFIFKSSML--LAWGIGCCLIYI---QIVTN-NF 615

  Fly   677 KSSNCVVTSRWMLQVTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLRNHIHG---------- 731
            ..:.|:|..    .||.|.|..|...|         .|:|..|.........|:|
  Fly   616 SCTACIVVD----LVTFFFLTSLLCLA---------WYKNVCWWKSGRYEFRIYGKYSCMAFHIF 667

  Fly   732 -------SQKGDVYA------FAII----------MYE--------------------------- 746
                   |.:..||.      :|:|          |||
  Fly   668 EKIQHSVSLRITVYLGILFSYYAVISLIMLNCDRDMYELSYIESKIYHYEMDRDTCFHPWVFTNM 732

  Fly   747 ---IFSRKGPFGQINFEPKEIVDYVKKLPL---------------KGEDPFRPEVESIIEAESCP 793
               |......|.:|.|..|.::...:.|..               ....||       ::||
  Fly   733 ISLILGISYTFARIPFGLKIVISCCETLAYLLIVFFQFAFIFQHSATTTPF-------MKAE--- 787

  Fly   794 DYVLACIRDC------WAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVT 852
              :..|:|.|      :|:  |.:.||:...|                       |..|::
  Fly   788 --LAHCLRVCMMLLTMYAK--ERQSEFNTKMN-----------------------YKLNVD---- 821

  Fly   853 ERTRLLCEEKMKTED--------LLHRMLPQSVAEKLTMGQGVEPVSYD---LVTIYFSDIVGFT 906
                  .:.|.|..|        ||:.:||..|.:..........:.|:   :|::.|:.::.|
  Fly   822 ------LQNKQKAADLTNQSIIILLNNILPSHVVDLYLNSLAKHELYYENYRMVSVMFAMLINF- 879

  Fly   907 AMSAESTPLQV--VNFLNDLYTVFDRIIRGYDVY----KVETIGDAYMVVSGLP------IKNGD 959
                   |:.:  :..|||:.|.|||::..|..|    |::.:|..||...||.      |:..|
  Fly   880 -------PMNLPSLRVLNDIITQFDRLLTAYREYYVVEKIKVVGCTYMAACGLDFNLASNIRQTD 937

  Fly   960 RHAGEIASMALELLHAVKQHRIAHRPNE---------------------TL-------------- 989
            ....  :|:.:|:.|| :.||:.....:                     ||
  Fly   938 HFRN--SSLHVEVEHA-RNHRMTDENYDSDMNNDEVVFIMTTFALDLMRTLAACNRAYSSSFFER 999

  Fly   990 -----KLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGG 1049
                 |:.||:.:|.::|||||.:.|.|.::|:.||.||||||.|....|.::.:....|.:...
  Fly  1000 SLSQGKICIGISSGEIMAGVVGASQPHYDIWGNPVNMASRMESTGLPGHIQVTEESAKILQEFDI 1064

  Fly  1050 GYITEKRGLVNMKGKGDVVTWWLTGANENA--IQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQPS 1112
            ..|  .||:..:||:||:.|::: |.:||.  :..|||:.     .|..|......|:|||.:.|
  Fly  1065 KCI--YRGMTFVKGRGDIPTYFV-GIDENLKFMSAKLVNR-----SLSRRFSVMSSLDPDSLRKS 1121

  Fly  1113  1112
              Fly  1122  1121

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593	60/294 (20%)
		PK_GC-A_B	543..827	CDD:270944	75/409 (18%)
		HNOBA	<833..881	CDD:462234	10/55 (18%)
		CYCc	860..1052	CDD:214485	61/254 (24%)
ACXC	NP_609593.1	Nucleotidyl_cyc_III	307..466	CDD:448371	24/185 (13%)
		Nucleotidyl_cyc_III	861..1085	CDD:448371	61/236 (26%)