Protein Alignment CG42637 and gcy-27

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: NP_001255957.2
• Gene: gcy-27 / 191654
• WormBaseID: WBGene00001550
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 188/602 - (31%)
• Similarity: 313/602 - (51%)
• Gaps: 71/602 - (11%)

  Fly   515 RKWKIELEIEGLLWKIDPNEIKGYSGNEIVSSPSKVSLM-SAQSYGSRWTNQFVTSTGRLRG--A 576
            ||:|       :.||:....:|     .||:..:...:. ..::..::.....:||..|:.|  |
 Worm    29 RKYK-------MTWKVPKESLK-----IIVNKNADARMQRELENRTAKDEANALTSRRRVFGSYA 81

  Fly   577 VVRIKELKFPRKR-----DISREIMKEMRLLRELRHDNINSFIGASV--EPTRILLVTDYCAKGS 634
            ::..:..:|.:.|     ||:...:..:..|::|:|||:.:|.|..:  :...:.::.....:|:
 Worm    82 LIGTQRAEFIQFRQIKHIDITNASLDFLYNLKQLKHDNLANFYGIQLNDDLNTMTILHALVERGT 146

  Fly   635 LYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHEL 699
            |.:...:.|..:|:.|.::.:.|::||:.|:|.|.:.|||:|.::.|::...|:|::..:|:...
 Worm   147 LEEFCLDRDFGMDETFKSAFMRDILKGLQYLHLSPVAYHGHLHAATCLIDINWVLKIALYGVTNF 211

  Fly   700 RQC----AENESIGEHQ----HYRNQLWRAPELLRNH----------IHGSQKGDVYAFAIIMYE 746
             .|    |||.::.:..    .|...:...||.:|.:          :.||::||:|...:|.|.
 Worm   212 -VCDNFDAENITMPDRSDYTISYAQYVCFPPEHIREYDATGKLPTRFVRGSKQGDIYCVGMIFYM 275

  Fly   747 IFSRKGPFGQINFEPK-------EIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCW 804
            :..|:.|:..|:...:       ||:|:       ...||      |...|:..|.:|...::||
 Worm   276 MIEREDPYRLIHSVERPGSGLMMEILDH-------NLMPF------ISNNETQEDTLLDKCKECW 327

  Fly   805 AEDPEERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLL 869
            ..|||:||....:||.:.........|::|||:.|.||||:.||.:|..|:..|...:|:|..||
 Worm   328 NRDPEKRPTIENLRNAIAICYADSKGNLIDQMIRMNEKYADELETLVAARSADLALAQMQTMRLL 392

  Fly   870 HRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRG 934
            :.|||.|:|:.|..|......||...|:.|..|..|..:.....|.:|:.||||::..||.:|:.
 Worm   393 NEMLPASIAKDLKNGVIAPARSYASATVMFVQICDFIVILKRRPPKEVIGFLNDIFDQFDTVIKR 457

  Fly   935 YDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGP 999
            :|.|||||.|:.|||.||:|.:|..||..|:|.|:||:......:.:.:..|..|::|||.|.||
 Worm   458 HDAYKVETTGETYMVASGVPNENEGRHVFEVAEMSLEIRAISLSYTLENDKNYKLRVRIGFHAGP 522

  Fly  1000 VVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKI---HISNKCKLALDKLGGGYITEKRGLVNM 1061
            :.|||:|:..|||||||||||.||||:||...|:|   .|:.:..||..:    |...|||:|::
 Worm   523 IAAGVIGIKNPRYCLFGDTVNFASRMQSNCPPLQIQTSEITARMLLATHE----YKLVKRGIVHV 583

  Fly  1062 KGKGDVVTWWLTGANEN 1078
            ||||:|..:||   ||:
 Worm   584 KGKGEVNCYWL---NEH 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593
		PK_GC-A_B	543..827	CDD:270944	73/318 (23%)
		HNOBA	<833..881	CDD:462234	22/47 (47%)
		CYCc	860..1052	CDD:214485	81/194 (42%)
gcy-27	NP_001255957.2	Protein Kinases, catalytic domain	75..338	CDD:473864	67/276 (24%)
		CYCc	383..573	CDD:214485	81/193 (42%)