Protein Alignment CG42637 and Npr3

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: NP_032754.2
• Gene: Npr3 / 18162
• MGIID: 97373
• Length: 536
• Species: Mus musculus
• Alignment Length: 579
• Identity: 118/579 - (20%)
• Similarity: 223/579 - (38%)
• Gaps: 139/579 - (24%)

  Fly     9 LLLLSVAVRDCSNHRTVLTVGYLTALTGDL------KTRQGLAISGALTMALDEVNKDPNLL--- 64
            |||.:.:.  |.....||..|..::..||.      :.|:.||......:.|  :.:|.:.|
Mouse     4 LLLFTFSA--CVLLARVLLAGGASSGAGDTRPGSRRRAREALAAQKIEVLVL--LPRDDSYLFSL 64

  Fly    65 ----PNVYLDLRWNDTKG-----------------DTVLATKAITEMICDGIATIFGPE-----G 103
                |.:...||..:..|                 |:....:|:..:: |.:|...|.:     |
Mouse    65 ARVRPAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLV-DRVAAARGAKPDLILG 128

  Fly   104 P-C-YVEAIVSQSR---NIPMIS---------YKCAEYRASAIPTFARTEPPDTQVVKSLLALLR 154
            | | |..|.|::..   ::||:|         :|..||     ....|..|...::.:.:|||.|
Mouse   129 PVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEY-----SHLTRVAPAYAKMGEMMLALFR 188

  Fly   155 YYAWNKFSILYED---------VWSPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRS 210
            ::.|::.:::|.|         ....|.::.:::..       |..::..:..|..:  ||
Mouse   189 HHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGL-------HTSAYNFDETKDLD--LD---- 240

  Fly   211 GYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRR 275
                .:|:......|:.:...:.:::...|.::...|: ..|:|....:::. .|....:...||
Mouse   241 ----DIVRYIQGSERVVIMCASGDTIRRIMLAVHRHGM-TSGDYAFFNIELF-NSSSYGDGSWRR 299

  Fly   276 VDQITFMSNCHSTENFNQMARSLLVVASTPPTK-DYIQFTKQVQKYSSKPPFNLEIPRLFVESNF 339
            .|:       |.:| ..|...||..|......| ::.:|:.:|:....|...|.|
Mouse   300 GDK-------HDSE-AKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNEE---------- 346

  Fly   340 SKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSK 404
             .:::::....:|::.||..|:.::||....          ..:|.::|.. ..|||:..|.| :
Mouse   347 -DYVNMFVEGFHDAILLYVLALHEVLRAGYS----------KKDGGKIIQQ-TWNRTFEGIAG-Q 398

  Fly   405 IKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLINGSIDWPSGGEK 469
            :.||..||..|:|||:|        ..:.......|...||  |:| ..::: ..::.:|.|..|
Mouse   399 VSIDANGDRYGDFSVVA--------MTDTEAGTQEVIGDYF--GKE-GRFQM-RSNVKYPWGPLK 451

  Fly   470 -PADEP-MCGFANEL-CKKDDTHYTSTVAAVVLGVLLFCSGVITMSIY---RKWKIELE 522
             ..||. :....|.. ||.......|.|..:|:|.||  ...:.|:.|   :|::|.:|
Mouse   452 LRLDETRIVEHTNSSPCKSSGGLEESAVTGIVVGALL--GAGLLMAFYFFRKKYRITIE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593	90/477 (19%)
		PK_GC-A_B	543..827	CDD:270944
		HNOBA	<833..881	CDD:462234
		CYCc	860..1052	CDD:214485
Npr3	NP_032754.2	PBP1_NPR_C	46..441	CDD:380609	87/464 (19%)
		TM_EphA1	471..502	CDD:214014	8/32 (25%)