Protein Alignment CG42637 and LOC1280524

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_061518472.1
• Gene: LOC1280524 / 1280524
• VectorBaseID: AGAMI1_000821
• Length: 1259
• Species: Anopheles gambiae
• Alignment Length: 1243
• Identity: 511/1243 - (41%)
• Similarity: 705/1243 - (56%)
• Gaps: 144/1243 - (11%)

  Fly    25 VLTVGYLTA---LTGD-LKTRQGLAISGALTMALDEVNKDPNLLPNVYL-----DLRWN--DTKG 78
            |.||||||.   ..|| :..|.||.||||:|:|:.|||       :.|.     :||:.  :|.|
Mosquito    68 VFTVGYLTGSQRRPGDRVYARPGLQISGAITLAMTEVN-------DRYFSQHGHELRFEVAETYG 125

  Fly    79 DTVLATKAITEMICDGIATIFGPEGPCYVEAIVSQSRNIPMISYKCAEYRAS---AIPTFARTEP 140
            :.|.:.:...::....:....||:..|..|..::.:.|:|||||.|.....|   ..||||||.|
Mosquito   126 EEVTSIRKTADLWTRDVIAYLGPQETCVHEGRMAAAFNLPMISYFCTHNETSNKKHFPTFARTRP 190

  Fly   141 PDTQVVKSLLALLRYYAWNKFSILY----EDVWSPVADLLKDQATKRNMTINHKQSFIDNRVKCC 201
            ||.|:.||:::||..|.|.:.|.||    ......||:.||  .|.|...|         |::..
Mosquito   191 PDLQISKSVVSLLLAYNWTQVSFLYRASDNGELDAVAETLK--TTLRTANI---------RIRSV 244

  Fly   202 EQMLDCCRSGY----WYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMM 262
            ....|....||    :.:||::|...||||:.||.....:..:.|:...||..||:|.|:.||:.
Mosquito   245 GTWTDIYHHGYSSNPFERLVEDTYEDTRIYLVLGYHYEHIGLLVSLRRRGLLDRGDYFVVGVDID 309

  Fly   263 VYSEREAEKYLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFN 327
            .|......||:..:.|.|  .:..:.|.|    |..|.:..:.|.: :.:|..:|.||...||||
Mosquito   310 QYDAALPTKYMHGLLQTT--PDPDAVEAF----RHYLGIVPSAPVR-FEEFAVKVNKYLELPPFN 367

  Fly   328 LEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTII 392
            .....:|...  .|.|...||||||:|.|||.|:.::|.....          ..||:.:|:. |
Mosquito   368 YRNALIFFGG--VKQIRAEAAYLYDAVHLYANALMQVLLSGGS----------PKNGSAIIEA-I 419

  Fly   393 KNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQG--EEHP--- 452
            |.|.|:|..|..:.||:.||:.||:::||.||.....:.|   .|.:.|:..|...  :..|
Mosquito   420 KGRAYISAMGYLVHIDENGDATGNYTILARKPVPSTGTTN---QYGLFPIGRFSSPTVDRIPFKI 481

  Fly   453 -EYKLINGSIDWPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRK 516
             |.:|.: :|||...| .|..||.|||..|.|    ..||..:...:.|..|...||:::.:||.
Mosquito   482 QEIRLFD-TIDWVGSG-PPVAEPRCGFRGEKC----ISYTGEITGGIAGGALLLLGVVSLVLYRN 540

  Fly   517 WKIELEIEGLLWKIDPNEI------KGYSGNEIVSS------PSKVSLMSAQSYGSRWTNQFVTS 569
            |:.|.|::.||||:|..||      |..:|.::..|      .|:|||.|......|::..| |.
Mosquito   541 WRYEQELDSLLWKVDFREIQMHENEKETAGQKMTRSTHPLIRTSQVSLSSNPDLDFRYSTIF-TP 604

  Fly   570 TGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGS 634
            .|..:|.:..||::| .:..||:||:.||::|||::||||:|:||||..:|..|.::||||.:||
Mosquito   605 IGLYKGQLYAIKKVK-KKSIDITREMKKELKLLRDMRHDNLNAFIGACTDPPNICIITDYCNRGS 668

  Fly   635 LYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHEL 699
            |.|::||||:|||::|.||::.|:::||||:|:|.|.:||:|::|||::.|||:::::||||...
Mosquito   669 LKDVLENEDVKLDNMFTASMVADILRGMIYLHDSPLRFHGSLRTSNCLIDSRWVVKLSDFGLFAF 733

  Fly   700 RQCAE---NESIGEHQHYRNQLWRAPELLR----NHIHGSQKGDVYAFAIIMYEIFSRKGPFGQI 757
            :|.:|   :|.....:..:..|:|||||||    ..:.|:.|||||:|.|::||||:|:||||:|
Mosquito   734 KQGSEEVPDEKEKLEEKCQKLLYRAPELLRAGPTATVPGTPKGDVYSFGIVLYEIFTRRGPFGEI 798

  Fly   758 NFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLK 822
            ...|.|.:..|.. ||....||||.::.:   |:..|.|..|:::||||.||:||:|..|||||:
Mosquito   799 ECTPMECLKRVLN-PLDPNTPFRPAIQPL---ETSFDCVRDCLKECWAERPEDRPDFKTIRNRLR 859

  Fly   823 KMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGV 887
            .:|.|...||.|.||.||||||||||.:|.|||..|.|||.|||.||..|||:.|||:|..|..|
Mosquito   860 VLRKGMRPNIFDNMMAMMEKYANNLEQLVDERTDQLQEEKKKTEALLLEMLPRPVAEQLKRGHKV 924

  Fly   888 EPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSG 952
            |..||||||||||||||||:|||||||||||:|||||||.||.||..||||||||||||||||||
Mosquito   925 EAESYDLVTIYFSDIVGFTSMSAESTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSG 989

  Fly   953 LPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGD 1017
            |||:||..||.|||||:|:||.||.:.::.||||:.|.||||:|:|||.||||||.|||||||||
Mosquito   990 LPIRNGLIHAAEIASMSLQLLEAVAEFKVRHRPNDRLYLRIGIHSGPVCAGVVGLKMPRYCLFGD 1054

  Fly  1018 TVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQK 1082
            ||||||||||.|:.||||.|.:.|..||.| |||..::||||.||||||..|:||.|.:.:|..:
Mosquito  1055 TVNTASRMESTGQPLKIHCSLQTKEILDSL-GGYQFQERGLVPMKGKGDQRTFWLVGEDPDARAR 1118

  Fly  1083 KLVDMMDMPPPLFSRPRKSPKLNPDSRQPSIQAMHFCGTGSRRQSTVPRAMDGESTYSL---QGS 1144
            :..:..:.        |.|..||           .:.|. .:..:.:|.......:.||   :||
Mosquito  1119 RTKERTER--------RGSRALN-----------KYLGM-LKSVTNLPGVRSSLKSRSLGLPRGS 1163

  Fly  1145 VRESPRMVSKRDRDRERPPINGLGAGHFVGGALLE-------SAQASLSTLNHSETNETNCDMDG 1202
            :   ||..|.....|.|          |..||:||       |..|.:..::.|....::..:..
Mosquito  1164 L---PRSSSLESPKRLR----------FASGAMLEQHRYHRYSDDALMEVISDSSIRRSDYSISD 1215

  Fly  1203 GSGGVSGS 1210
            |:..::.|
Mosquito  1216 GAEDITAS 1223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593	141/440 (32%)
		PK_GC-A_B	543..827	CDD:270944	130/296 (44%)
		HNOBA	<833..881	CDD:462234	32/47 (68%)
		CYCc	860..1052	CDD:214485	141/191 (74%)
LOC1280524	XP_061518472.1	None