Protein Alignment CG42637 and LOC1275535

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_061514001.1
• Gene: LOC1275535 / 1275535
• VectorBaseID: AGAMI1_002344
• Length: 1206
• Species: Anopheles gambiae
• Alignment Length: 1186
• Identity: 389/1186 - (32%)
• Similarity: 587/1186 - (49%)
• Gaps: 214/1186 - (18%)

  Fly    18 DCSNHRTVLTVGYLTALTGDLKTRQGLAISG-ALTMALDEVNKDPNLLPNVYLDLRWNDTKGDTV 81
            |.:|: ||..||.|.|  ..|.:...|...| |:.:||:.||:....:.||.|      :|....
Mosquito   123 DDTNY-TVYHVGVLMA--SHLDSPFDLERCGPAIDLALELVNQSLMKVHNVRL------SKVQRS 178

  Fly    82 LATKAITEMICDG---------------IATIFGPEGPCYVEAIVSQSRNIPMISYKCAEYRASA 131
            .||       |.|               :....||.....:|.:.           :.|:|..:.
Mosquito   179 YAT-------CSGSKSPGLAADLHFKHSVIAFIGPACAFALEPVA-----------QLADYWNTP 225

  Fly   132 IPTFARTEPP---DTQVVKSLLALL----------------RY-------YAWNKFSILYEDV-- 168
            |.|....:||   :..|...:|..|                ||       |...:..:::..:
Mosquito   226 IITGMGDQPPSEGELSVTSGILGRLSNRWKNDSSGMFKDKSRYQTLTRMSYCQCRLKLVFSSIFR 290

  Fly   169 ---WSPVADLLKDQATKRNMTI--NHKQSFIDNRVKCCEQMLDCCR--SGYWYQLVQNTMNRTRI 226
               |..:| |:.|::...::|:  |.:....|      |::|...|  .|...:.::..:....:
Mosquito   291 QFGWRHIA-LIIDRSDLFSLTVGKNLEYGLKD------EELLKFVRELDGNDEEDIEAYLKDASM 348

  Fly   227 Y---VFLGAANSLV-DFMSSMETAGLFARGEYMVIFVDMMVY-SEREAEKYLRRVDQITFMSNCH 286
            |   :.|....||| .||.|....|: .|||:  .|:|:.:: |....:.|....|:..|.:
Mosquito   349 YARVIILSVRGSLVRKFMLSALALGM-TRGEF--TFLDVEIFQSSYWGDHYWELGDEDDFKA--- 407

  Fly   287 STENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFNLEIPRLFVESNFSKFISIYAAYLY 351
                 .:...:||.|:...||....|:..:..:..:|..:|.    .|||   .:.::.:....:
Mosquito   408 -----RKSYEALLRVSLLQPTSPTYQYFAEKVRALAKQDYNY----TFVE---DEEVNFFIGAFF 460

  Fly   352 DSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSKIKIDQYGDSEGN 416
            |.|.|...|::..|.|...:          .:|| .|...:..|.:..||| .::||..||.:.:
Mosquito   461 DGVYLLGMALNDTLNEGGDI----------RDGT-AITRKMWGRDFEGITG-HVRIDDNGDRDAD 513

  Fly   417 FSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEYKLING-SIDWPSGGE-KPADEPMCGF- 478
            :|:|...          |.......||:::....  ||..:.| .|.||.|.| .|.|.|.|||
Mosquito   514 YSILDLD----------PITGRFEVVAHYYGITR--EYSPVKGKKIHWPGGREGPPPDVPKCGFL 566

  Fly   479 -ANELCKKDD---THYTSTVAAVVLGVLLFCSGVITMSIYRKWKIELEIEGLLWKIDPNEI---- 535
             .:..|:.:.   ..|    ..|..|::...:..:|..:.::.|:..|:..:.|::.|:|:
Mosquito   567 GTSPACQGNGDMIIRY----GLVGFGIISAFAAAVTYILCKQMKLNSELNNMSWRVRPDEVLLEV 627

  Fly   536 ---------------KGYSGNEIVSSPSKVSLMSAQSYGSRWTNQFVTSTGRLRGAVVRIKELKF 585
                           :.:|..:...:..:||:.|.   .|:...|..|:.|..:|..|.||::.
Mosquito   628 GKMFGSKMGLQKLNYENFSLQQFGLNSGRVSIASG---NSQLPAQLFTTIGIYKGERVAIKKVA- 688

  Fly   586 PRKRDISREIMKEMRLLRELRHDNINSFIGASVE---PTRILLVTDYCAKGSLYDIIENEDIKLD 647
            .:|..|:..::.|::..|::.|:|...|:||.::   || ||::|:||.||||.|::|||.|:||
Mosquito   689 KKKVYITSTLLWEIKQARDVSHENTVRFVGACIDLPRPT-ILILTEYCPKGSLKDVLENEAIQLD 752

  Fly   648 DLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQCAENESIGEHQ 712
            ..|..|||||::|||.|:|||.:..||.|:|.||::..|::|:::||||..|  ...:|.:.:..
Mosquito   753 WNFRMSLIHDVVKGMAYLHNSDVGVHGKLRSCNCLIDGRFVLKISDFGLRTL--TTPSEYVRDQN 815

  Fly   713 HYRNQLWRAPELLRNHI----HGSQKGDVYAFAIIMYEIFSRKGPFGQIN--FEPKEIVDYVKKL 771
            :|...||.|||||...:    ..:||||||:||||:.||..|.||:....  .:|:.||:   ::
Mosquito   816 YYNKLLWVAPELLPATVIPGTPATQKGDVYSFAIILEEIVVRGGPYETARQFLDPQAIVE---RV 877

  Fly   772 PLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGGKTKNIMDQM 836
            .|....||||    .:....||..:|..:..||::.|::||.||.||:.::.:..|..:|:||.:
Mosquito   878 ALHESPPFRP----FVGQRDCPPDLLDLMEKCWSDSPDDRPTFSGIRSSVRLIMKGFCENLMDDL 938

  Fly   837 MEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSD 901
            :..||:||||||.:|.|:|..|..||.:||:||:::||:.||::|..|:.|:|..::.|||||||
Mosquito   939 LRRMEQYANNLESLVEEKTEQLSMEKRRTEELLYQVLPRPVAQQLLAGEMVQPEQFECVTIYFSD 1003

  Fly   902 IVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIA 966
            ||||||:.|:|.|::||:||||||:.|||||..||||||||||||||||||||.:||..||.||.
Mosquito  1004 IVGFTALCAQSRPMEVVDFLNDLYSTFDRIIGFYDVYKVETIGDAYMVVSGLPERNGHDHAREIG 1068

  Fly   967 SMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEA 1031
            .|||.:|.||:...|.|:|...||:|||:|:|||.|||||..||.||||||||||||||||.|..
Mosquito  1069 LMALAILDAVRSFTIKHKPEYQLKIRIGIHSGPVCAGVVGQKMPHYCLFGDTVNTASRMESTGHP 1133

  Fly  1032 LKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMDMPPPLFS 1096
            ||||:|...|..|||. |.:.||.||.|.:||||.|.|:||...:|
Mosquito  1134 LKIHVSEAAKQILDKF-GTFRTELRGDVELKGKGIVTTYWLLECSE------------------- 1178

  Fly  1097 RPRKSPKLNPDSRQPS 1112
                     ||.|.|:
Mosquito  1179 ---------PDPRPPT 1185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593	97/474 (20%)
		PK_GC-A_B	543..827	CDD:270944	108/292 (37%)
		HNOBA	<833..881	CDD:462234	24/47 (51%)
		CYCc	860..1052	CDD:214485	121/191 (63%)
LOC1275535	XP_061514001.1	None