Protein Alignment CG42637 and LOC1269185

DIOPT Version :10

• Sequence 1: NP_524165.2
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_061497707.1
• Gene: LOC1269185 / 1269185
• VectorBaseID: AGAMI1_001998
• Length: 1357
• Species: Anopheles gambiae
• Alignment Length: 1282
• Identity: 440/1282 - (34%)
• Similarity: 662/1282 - (51%)
• Gaps: 202/1282 - (15%)

  Fly    50 LTMALDEVNKDPNLLPNVYLDLRWNDTK-GDTVLATKAITEMICDGIATIFGPEGPC-YVEAIVS 112
            :.||...|.....||.|:.:::.:.||: ..|..|..|....:.......|||  .| ||.|.::
Mosquito   162 IEMATRVVTAPGGLLQNLRIEIDYRDTQCSSTYGALGAFDIFLKRKPDVFFGP--ICDYVIAPIA 224

  Fly   113 QSRN---IPMI---------SYKCAEYRASAIPTFARTEPPDTQVVKSLLALLRYYAWNKFSILY 165
            :..:   ||:|         :.|...||     |..|...........:..:.|:|.|...:.||
Mosquito   225 RYSSVWGIPLITSGGLTEAFTLKAPHYR-----TLTRMMGNYHAFGLMMREIHRHYNWTIQAYLY 284

  Fly   166 EDVWSPVADLLKDQATKRNMT--------INH--------KQSFIDNRVKCCEQMLDCCRSGYWY 214
            .:.         |:.:.|..|        ||.        ..:|.:...|..:          :.
Mosquito   285 HEF---------DEKSGRGFTDCSMAITSINRAIGGNETSSGTFDEETAKYAD----------YL 330

  Fly   215 QLVQNTMNRTRIYVF---------LGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAE 270
            :|::|...|.||:::         ..:.:::.:.|.:.....:...|||  :|.::.::....|.
Mosquito   331 RLLRNIKKRARIHLYRRDLVVVIMCASPSTIREIMLAAAELNMVNSGEY--VFFNIEIFGSMTAT 393

  Fly   271 K----YLRRVDQITFMSNCHSTENFNQMARS-----LLVVASTPPTKDYIQFTKQVQKYSSKPPF 326
            |    |.:           :.|:..||.|:.     |.|||..|..::|.||:|:| |..:|..:
Mosquito   394 KQPPWYAK-----------NDTDERNQKAKEAFTALLQVVAREPEDEEYRQFSKEV-KELTKTKY 446

  Fly   327 NLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLRE--ETRVLTDDVIFEVASNGTRVID 389
            |    ..:.|   .:.:|.:....||:|.|||:|::..:.:  ..|.|...:      |||.:..
Mosquito   447 N----HTYAE---DEPVSTFVTAFYDAVLLYAYALNDSIAQLGVERALRQPI------NGTHLAQ 498

  Fly   390 TIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEY 454
             ::..|::..|||: :.||..||...|:|:|...|.  .....:..||      |:..|.:..|.
Mosquito   499 -LMWGRSFKGITGN-VTIDSNGDRISNYSLLDLNPE--TGLFEVVANY------YYGGGLQFVEG 553

  Fly   455 KLINGSIDWPSGGEK-PADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKWK 518
            |    :|.|.....| |.|.|.|||...|| .|::.....:.::||||.:.|.|:.::..||.:|
Mosquito   554 K----AIHWAGDRTKAPPDRPTCGFDGSLC-PDNSLPGYAILSLVLGVCVVCMGIASIVGYRHYK 613

  Fly   519 IELEIEGLLWKIDPNEI------KGYSG--NEIVSSPSKVSLMSAQSYGSRWTNQFVTSTGRLRG 575
            :|.||..:.||::||::      :|:.|  :.:|...|:.::.|..........|.....|..:|
Mosquito   614 LEAEINSMTWKVNPNDVLSCNPSRGHRGSFHSMVKRGSQATIYSEDLNSLPGDRQIYIHFGFYKG 678

  Fly   576 AVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASV----EPTRILLVTDYCAKGSLY 636
            ..|.||::.. :...::|.:|.|.:.:::::||::..|.||.:    ||   .::|:||.||||.
Mosquito   679 CKVAIKKINV-QNLSLTRSLMLEFKRMKDIQHDHLVRFYGACLDLHPEP---FILTEYCPKGSLQ 739

  Fly   637 DIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQ 701
            ||:|||.||||.:|..||:||::|||.::|::.|..||:||||||||.||::|:|||||||:||:
Mosquito   740 DILENETIKLDWMFKISLMHDIVKGMAFLHSTDLHSHGSLKSSNCVVDSRFVLKVTDFGLHQLRR 804

  Fly   702 CAENESIGEHQHYRNQLWRAPELLRN---HIHGSQKGDVYAFAIIMYEIFSRKGPF--GQINFEP 761
            ..::..|..:.:::..||.||||||:   ...||||||||:|.||:.||.||:|||  |.....|
Mosquito   805 STDDADIESYAYWQKLLWTAPELLRDPQCPPAGSQKGDVYSFGIIIQEIVSRQGPFYLGTEEKSP 869

  Fly   762 KEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKM-R 825
            |||:..|:..|...:.||||:|:     ||..:.|...:..||:|:|.:||:||.::..::|: :
Mosquito   870 KEIIKLVRDGPGILDAPFRPKVD-----ESSYEDVNNIMIKCWSEEPTDRPDFSGLKTIIRKINK 929

  Fly   826 GGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPV 890
            ..::.||:|.:::.||:||||||.:|.|||:...|||.|.|:||:::||:|||.:|.||:.|...
Mosquito   930 ENESGNILDNLLQRMEQYANNLEALVDERTQDYFEEKRKCEELLYQLLPKSVAAQLIMGKSVIAE 994

  Fly   891 SYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPI 955
            :||.||||||||||||::||:|||:|||:.||||||.||.|:..:|||||||||||||||||||:
Mosquito   995 TYDQVTIYFSDIVGFTSISAQSTPMQVVDLLNDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPV 1059

  Fly   956 KNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVN 1020
            :||:.||.||:.|||.||.||.:..|.|||||.|:||||:|:||.|||||||.||||||||||||
Mosquito  1060 RNGNLHAREISRMALRLLAAVYKFTIRHRPNEQLRLRIGLHSGPCVAGVVGLKMPRYCLFGDTVN 1124

  Fly  1021 TASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQK--- 1082
            |||||||||||||||:|:..||.||..|...:|| ||||.|||||:::|:||.|....||..
Mosquito  1125 TASRMESNGEALKIHVSHTTKLLLDTFGTFDLTE-RGLVPMKGKGEMLTYWLNGERTEAIAAAPL 1188

  Fly  1083 ----KLVDMMDMPPPLFSRPRKSPKLNPDSRQPSIQAMHFCGTGSRRQSTVPRAMDGESTYSLQG 1143
                |::......|......|..|.|......|:       ....::...:|.|   .|...:.|
Mosquito  1189 PNGLKVMSPAGTSPASIMASRNGPTLLATDSVPA-------SDPQQQPLLLPTA---TSASQVNG 1243

  Fly  1144 SVRESPRMVSKRDRDRERPPINGLGAGHFVGGALLESAQASLSTLNHSETNETN----CDMDGGS 1204
            :|...|..:.          ||.....|               ..||:..|..|    |.::...
Mosquito  1244 TVASPPAGIL----------INHHNHHH---------------NNNHNNNNNNNNNSPCSINHNH 1283

  Fly  1205 GGVSGSGSGLVRQPNALHKPLAMVRPHRIISAAQLPQLGDNDDDSAD 1251
            ...|         |.:.|.|.|..:....:|.:.....|::..::::
Mosquito  1284 SNSS---------PISCHNPSAPAKKLNSVSYSFAKAPGNSSSNNSN 1321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_524165.2	PBP1_SAP_GC-like	26..445	CDD:380593	96/444 (22%)
		PK_GC-A_B	543..827	CDD:270944	118/293 (40%)
		HNOBA	<833..881	CDD:462234	25/47 (53%)
		CYCc	860..1052	CDD:214485	133/191 (70%)
LOC1269185	XP_061497707.1	None