DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42637 and Adcy7

DIOPT Version :10

Sequence 1:NP_524165.2 Gene:CG42637 / 40153 FlyBaseID:FBgn0261360 Length:1525 Species:Drosophila melanogaster
Sequence 2:XP_006530643.1 Gene:Adcy7 / 11513 MGIID:102891 Length:1146 Species:Mus musculus


Alignment Length:371 Identity:102/371 - (27%)
Similarity:157/371 - (42%) Gaps:86/371 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   788 EAESCPDYVLACIRDCWAEDP---EERPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYAN--NL 847
            :|:|.|.:.||         |   |..|..|.:...||.|..          ..::..||.  .|
Mouse   787 DAQSMPSHTLA---------PGARETAPSPSYLERDLKIMVN----------FYLILFYATLILL 832

  Fly   848 EDIVTERTRLLC--EEKMKTED------------LLHRMLPQSVAEKLTMGQGVEP---VSYDLV 895
            ...:....||.|  ::|.|.|.            ||..:||..||......:..|.   .|||.|
Mouse   833 SRQIDYYCRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKAAEDWYHQSYDCV 897

  Fly   896 TIYFSDI----VGFTAMSAESTPLQVVNFLNDLYTVFDRII---RGYDVYKVETIGDAYMVVSGL 953
            .:.|:.:    |.:|........|:.:..||::...||.::   :...|.|::|||..||..:||
Mouse   898 CVMFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGL 962

  Fly   954 PIKNGDR---------HAGEIASMALEL---LHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVG 1006
            ...:|..         |.|.:...::.|   |..:.:|..     .:.:||:|::.|||:|||:|
Mouse   963 SAPSGHENQDLERKHVHIGVLVEFSMALMSKLDGINRHSF-----NSFRLRVGINHGPVIAGVIG 1022

  Fly  1007 LTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWW 1071
            ...|:|.::|:|||.||||||.||..||.::.:....|.  |.||..|.|||:|:||||::.|::
Mouse  1023 ARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQ--GLGYSCECRGLINVKGKGELRTYF 1085

  Fly  1072 -----LTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQPS 1112
                 .....:..:...|:              :.|.|..||..||
Mouse  1086 ELFFLNPSVGQGFVSGSLL--------------RRPSLTTDSNTPS 1117

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42637NP_524165.2 PBP1_SAP_GC-like 26..445 CDD:380593
PK_GC-A_B 543..827 CDD:270944 12/41 (29%)
HNOBA <833..881 CDD:462234 15/63 (24%)
CYCc 860..1052 CDD:214485 66/225 (29%)
Adcy7XP_006530643.1 AcyC 48..456 CDD:441717
Guanylate_cyc 272..422 CDD:425528
Adcy_cons_dom 487..594 CDD:461877
Guanylate_cyc 890..1085 CDD:425528 67/201 (33%)
Blue background indicates that the domain is not in the aligned region.

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