DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42637 and LOC101732477

DIOPT Version :9

Sequence 1:	NP_001007096.1	Gene:	CG42637 / 40153	FlyBaseID:	FBgn0261360	Length:	1525	Species:	Drosophila melanogaster
Sequence 2:	XP_031757190.1	Gene:	LOC101732477 / 101732477	-ID:	-	Length:	690	Species:	Xenopus tropicalis

Alignment Length:	643	Identity:	263/643 - (40%)
Similarity:	371/643 - (57%)	Gaps:	76/643 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   470 PADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKWKIELEIEGLLWKIDPNE 534
            |||   ||    .|...    :|...|:||.:.|||||.|...::.:::.:..:....|.:...:
Frog    90 PAD---CG----PCPMP----SSIKIAIVLPLALFCSGFILALVWFQYQKQKMLWDESWILTVKD 143

  Fly   535 IKGYSGNEIVSSPSKVSLMSAQS----------------YGSRWTNQFVTSTGRLRGAVVRIKEL 583
            :.|  |.......|.:||...|:                .||. |:.|: .||...|.:|.:|.:
Frog   144 LPG--GTFHCGLGSTISLKCNQNSQPGHRPEMFANTVFICGSS-TDNFM-QTGIYDGRIVAVKRI 204

  Fly   584 KFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIENEDIKLDD 648
             :.:...||:.:.||::.:|:|.|.||..|||.||| ..|.::|:||.||||.|::.|:||.|:.
Frog   205 -YKKNFTISKTVRKEVQHVRKLDHPNICKFIGGSVE-GNIFIITEYCPKGSLADVLFNDDIPLNW 267

  Fly   649 LFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGL-----HELRQCAENESI 708
            .|..|...|:.:||.|:|..: :|||.|.|.||::..||:.:::|:||     .|.::..|.:..
Frog   268 GFRLSFATDIARGMAYLHQHK-IYHGRLTSRNCIIDDRWVCKISDYGLMVYRRDEFKEIMEKKPA 331

  Fly   709 GEHQHYRNQLWRAPELLRNH---IHGSQKGDVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKK 770
                    .::..||::.:.   :..:...|||::|||:.||.||..||      |..|  |:|
Frog   332 --------NIYCPPEVMNSDSKWVMPTASADVYSYAIILVEIASRCDPF------PGAI--YMK- 379

  Fly   771 LPLKGEDPFRPEVESIIEAES---CP---DYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGGKT 829
                 :..:||.:..:...::   ||   || ...::.|||.:|..||.|..||..|::|...|.
Frog   380 -----DASWRPRIPDLSAGKADHDCPNQADY-SELVKKCWAHNPLLRPSFEHIRKTLERMNPHKV 438

  Fly   830 KNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDL 894
            ..: |.||.:||||:.:||.:|.|||:.|.:||.||:.||:.|||:.||:.|..|...|..||..
Frog   439 SPV-DMMMNLMEKYSKHLEAVVAERTQDLLQEKQKTDRLLYSMLPKPVADDLRQGLMCEAQSYAN 502

  Fly   895 VTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGD 959
            .|::||||||||::|:.|||.|||:|||.|||:||.||..||||||||||||||||||:|.:||.
Frog   503 ATVFFSDIVGFTSISSASTPYQVVDFLNKLYTIFDDIIDNYDVYKVETIGDAYMVVSGVPKENGI 567

  Fly   960 RHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASR 1024
            :|..|||||||:|:......:|.|.|:..|::|.|:|:||||:||||..||||||||||||||||
Frog   568 KHVAEIASMALDLVSVCHSFKIPHIPDRNLQIRAGIHSGPVVSGVVGTKMPRYCLFGDTVNTASR 632

  Fly  1025 MESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQK 1082
            |||..|||||..|:.....|.|: ||||...||.:|:||||::.||||   .|...||
Frog   633 MESTSEALKIQCSSSAAELLQKI-GGYILTCRGALNVKGKGEMTTWWL---EEKETQK 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365
		ANF_receptor	48..412	CDD:279440
		PK_GC-A_B	543..827	CDD:270944	97/313 (31%)
		HNOBA	<835..881	CDD:285003	24/45 (53%)
		CYCc	860..1052	CDD:214485	116/191 (61%)
		Guanylate_cyc	887..1074	CDD:278633	116/186 (62%)
LOC101732477	XP_031757190.1	PKc_like	182..433	CDD:419665	92/278 (33%)
		HNOBA	<433..489	CDD:400168	27/56 (48%)
		CYCc	469..659	CDD:214485	116/190 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010