Protein Alignment CG42637 and gucy2f

DIOPT Version :9

• Sequence 1: NP_001007096.1
• Gene: CG42637 / 40153
• FlyBaseID: FBgn0261360
• Length: 1525
• Species: Drosophila melanogaster
• Sequence 2: XP_002931862.2
• Gene: gucy2f / 100492820
• XenbaseID: XB-GENE-480268
• Length: 1112
• Species: Xenopus tropicalis
• Alignment Length: 1150
• Identity: 362/1150 - (31%)
• Similarity: 572/1150 - (49%)
• Gaps: 214/1150 - (18%)

  Fly    49 ALTMALDEVNKDPNLLPNVYLDLRWNDTKGDTVLATKAITEMICDGIATIF-GPEGPCYVEA--I 110
            |..:|::.:|||.:|  ::.|...:...:.|...:....|.:...|:|:.| ||..|.|.:|  :
 Frog    79 AAKLAIERINKDASL--DLGLSFNYVILEEDCQTSKALSTFLTYSGVASGFIGPSNPGYCDAATL 141

  Fly   111 VSQSRNIPMISYKCAEY---RASAIPTFARTEPPDTQVVKSLLALLRYYAWNKFSIL--YEDVW- 169
            :.::.|..:.|:.|..|   ...:.||||||.|..|:|   |..:::|:.|....::  .||:|
 Frog   142 LGKNWNKAVFSWACINYELDNVKSYPTFARTLPSPTRV---LFNVMKYFQWAHVGVISSNEDIWR 203

  Fly   170 ---SPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLG 231
               ..||:.|:.......:.::     :.:.::..:|.|:..|.....:::...|:.    |.:|
 Frog   204 DTGRKVANALRSNGLPVGIVVS-----MGDDIRSTQQALEKVRKIDNIRMIIMCMHS----VLIG 259

  Fly   232 --AANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRRVDQITFMSNCHSTENFNQM 294
              |...|::....::    ...|.|:.:..|.:.||    ..|.:     |......::.|....
 Frog   260 GQAQQRLLEVAHDLK----MTDGTYVFVPYDTLYYS----LPYHK-----TTYDMLKNSPNLTAA 311

  Fly   295 ARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFNL---EIPRLFVESNFSKFISIYAAYLYDSVKL 356
            ..|:|.:......|.:.:..::.|: |.:...|:   ::..||             ..:|:::..
 Frog   312 YDSVLTITVESEGKTFYEAFQEAQE-SGEMNANIKPSQVSPLF-------------GTIYNAIYF 362

  Fly   357 YAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSK--IKIDQYGDSEGNFSV 419
            .|:|::...|:.|.|           :|:    :::|:...|...|..  ||.|..|:...::.:
 Frog   363 TAYAMNSSRRQGTWV-----------SGS----SLVKHSKNMQFYGFNQWIKTDMSGNGFTDYVI 412

  Fly   420 LAYKPHKWNNSNNMPCNYHMVPVAYFHQGEEHPEY---------KLINGSIDWPSGGEKPADEPM 475
            |         ..:|..|            |.|..|         :.:...|.:|: |..|..:..
 Frog   413 L---------DADMKTN------------ELHRTYVVDMETDMVRYMGRPIHFPN-GVSPKTDSY 455

  Fly   476 CGFAN-ELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYRKWKIELEIEGLLWKIDP--NEIKG 537
            |.|:: ::|       |..:......::..|   |.::|       :.:.||.:.|..  |:||
 Frog   456 CWFSDGKIC-------TGGIEPAFALMVFLC---IVVAI-------ISLNGLAYVIRRRINKIK- 502

  Fly   538 YSGNEIVSSPSKV--------------SLMSAQSYGSRWTNQ--FVTSTGRLR------------ 574
                 :|..|:|:              |:....:.|||.::.  .:|.|..::
 Frog   503 -----LVRGPNKILLTLEDVTFINPQLSVKKLSNDGSRTSDSGPVLTDTRSMKSPMRSGSTQSLI 562

  Fly   575 -------------GAVVRIK--------ELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASV 618
                         |..|.:|        ||| |...|:. |.||:|      ||:|:|.|:|...
 Frog   563 PATYENSNVAIYEGDWVWMKKFPSGDFGELK-PGTSDVF-ETMKDM------RHENVNPFLGFFH 619

  Fly   619 EPTRILLVTDYCAKGSLYDIIENEDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVV 683
            :.....:||::|::|||.|::.|:|:|||.:|.:||:.||||||.|:|:.:.| ||.|||.||||
 Frog   620 DCGVFAIVTEFCSRGSLEDLLRNQDVKLDWMFKSSLLLDLIKGMKYLHHRKFV-HGRLKSRNCVV 683

  Fly   684 TSRWMLQVTDFGLHELRQCAENESIGEHQHYRNQLWRAPELLR---NHIHGSQKGDVYAFAIIMY 745
            ..|::|:|||:|.:|:.: |:.....|...| ..||.||||||   :.:|||..||||:|::||.
 Frog   684 DGRFVLKVTDYGYNEVLE-AQRIPHEEPTAY-ELLWTAPELLRDPLSAVHGSFSGDVYSFSVIMQ 746

  Fly   746 EIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEE 810
            |:..|..||..:....:||:..|||.|        |....::..:..|...:..::.||.|.|:.
 Frog   747 EVVVRGPPFCTVEDTAEEIIQKVKKPP--------PLCRPMVSPDHAPMECIILMKKCWNEVPDR 803

  Fly   811 RPEFSVIRNRLKKMRGGKTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQ 875
            ||.|..|.::.|.:..|:..||:|.|:.|:|:|::||||::.|||..|..||.|||.||.:|||.
 Frog   804 RPSFDEIFDQFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPP 868

  Fly   876 SVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKV 940
            ||||.|.||..|||..:|.||:|||||||||::||.|.|::||:.||||||:||.:|..:|||||
 Frog   869 SVAEALKMGCTVEPEGFDEVTLYFSDIVGFTSISAMSEPIEVVDLLNDLYTLFDAVIGNHDVYKV 933

  Fly   941 ETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVV 1005
            |||||||||.||||.:||:|||.|||:|:|::|.:|...::.|.|:..:::|||:|:||.|||||
 Frog   934 ETIGDAYMVASGLPKRNGNRHAAEIANMSLDILSSVGSFKMRHMPDVPVRIRIGLHSGPAVAGVV 998

  Fly  1006 GLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTW 1070
            ||||||||||||||||||||||.|...:||::......|..|..||:.|.||...:||||...|:
 Frog   999 GLTMPRYCLFGDTVNTASRMESTGLPYRIHVNQSTVKTLRSLNEGYLLELRGRTELKGKGIEETF 1063

  Fly  1071 WLTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQPSIQA 1115
            ||.|      ::.....:.:||.:     ||.::.....|..|.|
 Frog  1064 WLVG------KEGFTKPLPVPPVI-----KSGQMGHGLLQDEITA 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42637	NP_001007096.1	PBP1_Speract_GC_like	26..445	CDD:107365	80/414 (19%)
		ANF_receptor	48..412	CDD:279440	76/381 (20%)
		PK_GC-A_B	543..827	CDD:270944	109/335 (33%)
		HNOBA	<835..881	CDD:285003	26/45 (58%)
		CYCc	860..1052	CDD:214485	118/191 (62%)
		Guanylate_cyc	887..1074	CDD:278633	112/186 (60%)
gucy2f	XP_002931862.2	PBP1_sensory_GC_DEF-like	58..439	CDD:380594	83/436 (19%)
		PK_GC-2D	553..820	CDD:270945	100/285 (35%)
		HNOBA	<829..874	CDD:400168	26/44 (59%)
		CYCc	853..1044	CDD:214485	117/190 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9642
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010