DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment serp and Cda5

DIOPT Version :9

Sequence 1:	NP_001262062.1	Gene:	serp / 40150	FlyBaseID:	FBgn0260653	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_722590.2	Gene:	Cda5 / 33158	FlyBaseID:	FBgn0051973	Length:	1998	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	143/369 - (38%)
Similarity:	216/369 - (58%)	Gaps:	29/369 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 APPCDPAVCVLPDCFCSEDGTSIPGDLPAKDVPMMITITFDDAINNNNIELYKEIF-KDRKNPNG 231
            |..|...||:||||:|.  |..|||:||.:.:|.::.:||||::|:.|.:||.::| |.|.||||
  Fly  1634 AAKCRKDVCLLPDCYCG--GRDIPGELPVESIPQIVLLTFDDSVNDLNKQLYTDLFEKGRVNPNG 1696

  Fly   232 CSIKATYFVSHKYTNYSAVQETARKGHEIAVHSITHNDEERFWSNATVDDWAKEMAGMRIITEKF 296
            |.|.||::|||::|:||.||.....|||:|.|:::|:..|:|    :...|.:|:||.|.|...:
  Fly  1697 CPITATFYVSHEWTDYSQVQNLYADGHEMASHTVSHSFGEQF----SQKKWTREIAGQREILAAY 1757

  Fly   297 ANITDNSVVGVRAPYLRVGGNNQFTMMEEQAFLYDSTITAPLSNPPLWPYTMYFRMPHRCHGNLQ 361
            ..:..:.|.|:|||:|.||||..:.|:.:..|.|||::....:.||.||||:.:::.|.|  .:.
  Fly  1758 GGVKMSDVRGMRAPFLSVGGNKMYKMLYDSNFTYDSSMPVYENRPPSWPYTLDYKIFHDC--MIP 1820

  Fly   362 SCPTRSH-AVWEMVMNELDRREDPVNDEYLPG--CAMVDSCSNILTGDQFYNFLNHNFDRHYDQN 423
            .|||||: .||::.|         |..:.|.|  |:|.|:|||....|.....:..||:|||..|
  Fly  1821 PCPTRSYPGVWQVPM---------VMWQDLNGGRCSMGDACSNPSDADGVTKMIMKNFERHYTTN 1876

  Fly   424 RAPLGLYFHAAWLKNNPEFLDAFLYWIDEILANHNDVYFVTMTQVIQWMQNPRTISEVKNFEPWR 488
            |||.||::||||. ..|...:.|:.::|.|.| ..||:.:|..|.:||:::|..||.:.:|:|:
  Fly  1877 RAPFGLFYHAAWF-TQPHHKEGFIKFLDAINA-MQDVWIITNWQALQWVRDPTPISRINSFQPF- 1938

  Fly   489 EKCVVEGKP-ACWVPNTCKLTSKEVPGETINLQTCVRCPNNYPW 531
             :|....:| .|..|..|.|..|   .....::||..||:.|||
  Fly  1939 -QCDYSDRPKRCNNPKVCNLWHK---SGVRYMKTCQPCPDIYPW 1978

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
serp	NP_001262062.1	CBM_14	48..105	CDD:279884
		LDLa	125..159	CDD:238060
		CE4_CDA_like_1	200..475	CDD:200596	109/278 (39%)
Cda5	NP_722590.2	CBM_14	58..106	CDD:279884
Cda5	NP_722590.2	CE4_CDA_like_2	1664..1926	CDD:200597	109/278 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4700
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1060206at2759
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	1	1.000	-	-		otm14253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	6.020