Protein Alignment serp and lgx-1

DIOPT Version :9

• Sequence 1: NP_001262062.1
• Gene: serp / 40150
• FlyBaseID: FBgn0260653
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001360720.1
• Gene: lgx-1 / 180825
• WormBaseID: WBGene00002983
• Length: 1754
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 181/565 - (32%)
• Similarity: 263/565 - (46%)
• Gaps: 113/565 - (20%)

  Fly    26 LRYKRQATTEETKKEESFEKELCKDKDAGEWFRLVAGEGDNC-RDVIQCTSSGLQ-AIR------ 82
            :|...|..::|.|.:.:...|.||:   ||   :.|| |..| .|..:|..:... |||
 Worm  1247 IRQNGQCISKECKHKVAKVGETCKN---GE---ICAG-GSICDYDRKRCICAAQHVAIRGICKQK 1304

  Fly    83 -CPAGLYFDIEKQTCDWKESVKNCKSKNKERRVKPLLHTDEPLCQDGFLACGDGNCIERGL---- 142
             .||   |.....||..:|   .|              |....|.:|...|.|.:..|.|.
 Worm  1305 SAPA---FAAPGDTCSMRE---KC--------------TGGATCFEGMCTCDDHHFAEDGYCRPI 1349

  Fly   143 --------FCNGEKDCSDGSDENTCDIDNDPNRAPPCDPAVCVLPDCFCSEDGTSIPGDLPAKDV 199
                    |.||.     |...::..:.| ..||..|:.|.|.||:|||:|:|...||.|...:.
 Worm  1350 EARSSKVQFVNGA-----GLRFSSMQVPN-RQRAQACNEAECKLPNCFCTENGRRAPGGLRPDET 1408

  Fly   200 PMMITITFDDAINNNNIELYKEIFKD--RKNPNGCSIKATYFVSHKYTNYSAVQETARKGHEIAV 262
            |..:.:|||||:|......||::|::  .||||||.:|||:|:||::|||.||....:|..|||.
 Worm  1409 PQFVVLTFDDAVNGKTFSDYKKLFENDVLKNPNGCDVKATFFISHEWTNYDAVNWLVQKNMEIAS 1473

  Fly   263 HSITHNDEERFWSNATVDDWAKEMAGMRIITEKFANITDNSVVGVRAPYLRVGGNNQFTMMEEQA 327
            :||:|...|    ||..:.|..||.|.|.|..||....:..:||:|:|.|.:||:|||.||....
 Worm  1474 NSISHESLE----NANTNRWLNEMDGQRRILAKFGGAPEEEIVGIRSPQLALGGDNQFEMMIGAE 1534

  Fly   328 FLYDSTITAPLSNP-----PLWPYTMYFRMPHRCHGNLQSCPTRSH-AVWEMVMNELDRREDPVN 386
            ||:|::::|   ||     |.||.||.:::...|  |..|||..|. .||.:          |:|
 Worm  1535 FLWDNSMSA---NPGIHGEPFWPQTMDYQVAWDC--NEASCPKSSFPGVWSV----------PLN 1584

  Fly   387 DEYLPGCAMVDSC--SNIL--------TGDQFYNFLNHNFDRHYDQNRAPLGLYFHAAWLK--NN 439
            ..|....:.:||.  |::|        |.|:....:..||:|.|..||||..|..:|.:|:  .:
 Worm  1585 QFYGSYMSQIDSFRRSSMLRAAVDLNNTVDELEEIITRNFERSYSANRAPYVLSLNADFLQLGGH 1649

  Fly   440 PEFLDAFLYWIDEILANHNDVYFVTMTQVIQWMQNPRTISEVKNFEPWREKCVVEGKP------- 497
            .:.:.|...:::.:.| ..|||.||:.|:|.||:.|..|||:|:     .|.|  |.|
 Worm  1650 NKGMKAVQKFLNRMSA-QKDVYIVTIKQLIDWMKRPVPISEMKS-----SKAV--GCPITLSFNR 1706

  Fly   498 -----ACWVPNTCKLTSKEVPGETINLQTCVRCPNNYPWVSDPTG 537
                 .|.:||.|..::..:..:.....||:.||..|||:.:|.|
 Worm  1707 NPSLSTCDIPNKCLYSTPSLSSQEHQFLTCLPCPTMYPWLENPAG 1751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
serp	NP_001262062.1	CBM_14	48..105	CDD:279884	19/65 (29%)
		LDLa	125..159	CDD:238060	10/45 (22%)
		CE4_CDA_like_1	200..475	CDD:200596	107/294 (36%)
lgx-1	NP_001360720.1	EB	322..382	CDD:366756
		PHA02682	<388..>493	CDD:177464
		EB	565..620	CDD:366756
		EB	609..666	CDD:366756
		EB	<718..757	CDD:366756
		EB	911..967	CDD:366756
		EB	956..1020	CDD:366756
		EB	1009..1083	CDD:366756
		EB	1072..1124	CDD:366756
		EB	<1215..1253	CDD:366756	1/5 (20%)
		EB	1242..1301	CDD:366756	18/60 (30%)
		EB	1290..1346	CDD:366756	17/75 (23%)
		CE4_CDA_like_1	1409..1684	CDD:200596	107/294 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4700
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	1	1.000	-	-		otm14253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.010