Protein Alignment serp and verm

DIOPT Version :10

• Sequence 1: NP_730444.1
• Gene: serp / 40150
• FlyBaseID: FBgn0260653
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: XP_061510370.1
• Gene: verm / 1280732
• VectorBaseID: AGAMI1_002244
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 317/547 - (57%)
• Similarity: 410/547 - (74%)
• Gaps: 17/547 - (3%)

  Fly     1 MAKLFVVFAVLALAAFNEASASDPLLRYKRQATTEETKKEESFEKELCKDKDAGEWFRLVAGEGD 65
            |||:..:|.:|.|.....|.     :|.|||  .|:...:....:|||||:...|:||| :.:||
Mosquito     1 MAKVIKLFGLLCLVVTIAAE-----VRVKRQ--DEDLDPDSINVEELCKDRPGDEYFRL-STDGD 57

  Fly    66 NCRDVIQCTSSG------LQAIRCPAGLYFDIEKQTCDWKESVKNCKSKNKERRVKPLLHTDEPL 124
             ||:|::|..:|      |..:|||.|||||:.:||||||.:||:|....|.|:|.|:|.||||:
Mosquito    58 -CREVVRCDDAGENGITRLAKVRCPTGLYFDVLRQTCDWKTNVKSCDLLGKPRKVLPILKTDEPI 121

  Fly   125 CQDGFLACGDGNCIERGLFCNGEKDCSDGSDENTCDIDNDPNRAPPCDPAVCVLPDCFCSEDGTS 189
            |.:|.|:||:|.||::.|||||:.||.|.||||.|.::.||||||.||...|||||||||.|||.
Mosquito   122 CPEGKLSCGNGECIDKELFCNGKPDCKDESDENACTVELDPNRAPDCDTTQCVLPDCFCSADGTR 186

  Fly   190 IPGDLPAKDVPMMITITFDDAINNNNIELYKEIFK-DRKNPNGCSIKATYFVSHKYTNYSAVQET 253
            |||::..:.||.||||||:.|:|.:||:||::||. .|:|||||.|:.|||||||||||||||:.
Mosquito   187 IPGNIEPQQVPQMITITFNGAVNVDNIDLYEDIFNGQRQNPNGCQIRGTYFVSHKYTNYSAVQDL 251

  Fly   254 ARKGHEIAVHSITHNDEERFWSNATVDDWAKEMAGMRIITEKFANITDNSVVGVRAPYLRVGGNN 318
            .||||||:|.|:||.|:..:|:..|.|||..||||.|:|.|:||||||.|::||||||||||||.
Mosquito   252 HRKGHEISVFSLTHKDDPTYWTQGTYDDWLAEMAGARLIVERFANITDGSIIGVRAPYLRVGGNK 316

  Fly   319 QFTMMEEQAFLYDSTITAPLSNPPLWPYTMYFRMPHRCHGNLQSCPTRSHAVWEMVMNELDRRED 383
            ||.||.:|.|:||::|||.|...|:||||:||||||:|:||..:||:|||.||||||||||||:|
Mosquito   317 QFEMMADQFFVYDASITASLGRVPIWPYTLYFRMPHKCNGNAHNCPSRSHPVWEMVMNELDRRDD 381

  Fly   384 PVNDEYLPGCAMVDSCSNILTGDQFYNFLNHNFDRHYDQNRAPLGLYFHAAWLKNNPEFLDAFLY 448
            |..||.||||.||||||||.:|:||...|.|||:|||:.|||||||:|||:|||:..|:.:..:.
Mosquito   382 PTFDESLPGCHMVDSCSNIQSGEQFGRLLRHNFNRHYNTNRAPLGLHFHASWLKSKKEYREELIK 446

  Fly   449 WIDEILANHNDVYFVTMTQVIQWMQNPRTISEVKNFEPWREKCVVEGKPACWVPNTCKLTSKEVP 513
            :|:|:| ..|||:||||.|||||||||..::.:::|:.|:|||.|:|:|.|.:||.|.||::|:|
Mosquito   447 FIEEML-GRNDVFFVTMLQVIQWMQNPTELNALRDFQEWKEKCDVKGQPYCSLPNACPLTTRELP 510

  Fly   514 GETINLQTCVRCPNNYPWVSDPTGDGF 540
            |||:.|.||:.|||||||:.|||||||
Mosquito   511 GETLRLFTCMECPNNYPWILDPTGDGF 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
serp	NP_730444.1	CBM_14	48..105	CDD:426342	31/62 (50%)
		LDLa	125..159	CDD:238060	20/33 (61%)
		CE4_CDA_like_1	200..475	CDD:200596	179/275 (65%)
verm	XP_061510370.1	None