DRSC/TRiP Functional Genomics Resources

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Protein Alignment LOX and teq

DIOPT Version :10

Sequence 1:NP_002308.2 Gene:LOX / 4015 HGNCID:6664 Length:417 Species:Homo sapiens
Sequence 2:NP_648288.2 Gene:teq / 39048 FlyBaseID:FBgn0023479 Length:2792 Species:Drosophila melanogaster


Alignment Length:437 Identity:86/437 - (19%)
Similarity:108/437 - (24%) Gaps:168/437 - (38%)


- Green bases have known domain annotations that are detailed below.


Human    24 PAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRRDPGAAVPGAANASAQQPR 88
            |..|..||            .|..::.||          .|||......|...|.......||| 
  Fly  1094 PFEGYHQP------------NQSSYQTNG----------GYQPPLPPHGGYQPPSQTYGGFQQP- 1135

Human    89 TPILLIRDNRTAA---ARTRTAGS--------------SGVTAGRPRPTARHWFQA--------- 127
                    |||..   ..::|.|.              :.:..|..:|.....|||         
  Fly  1136 --------NRTYEDFHNPSQTVGGFQPPYSVKGGYQPHNQLNGGYNQPNQSSSFQANGGYQPPSQ 1192

Human   128 ---GYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYK--YSDDNPYYNYY 187
               ||.||.....|...........:||:..|.....||||..|..|.|...  |...|.....|
  Fly  1193 VNRGYQTSFESNGGYQPPLETNKGHQVPSQINGGYQPRVDGNRGYQPPNELNGGYQPPNELNGAY 1257

Human   188 DTYERPRP---GGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTA 249
                 |.|   .|.|:|                                     ..|.|    ..
  Fly  1258 -----PAPSQLNGGYQP-------------------------------------PLEGN----LG 1276

Human   250 YRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQ-HYHSMDEFSHYDLLDANTQR 313
            ||              |...:|.|.....||...|...:.|... ||...|              
  Fly  1277 YR--------------PLSQQNSGYQPPQPSTGGYQPPFQSTGSGHYPGQD-------------- 1313

Human   314 RVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYG--ADID-------CQWIDITDV 369
                            ..|.......|.....||.|..:|..|  ..||       ||.:|:..|
  Fly  1314 ----------------APYAIPTPLLCPEKISGLFPNPFDATGYLTCIDGHTLPRQCQPLDVFSV 1362

Human   370 KPGNYILKVSVNPSYLVP---ESDYTNNVVRCDIRYTGHHAYASGCT 413
            ..|..:.:..||.:..||   ...|.:|.:.|...:.|...|...|:
  Fly  1363 SQGYCLPEQHVNKTDRVPFERTQTYQDNSLDCPRDFLGFVVYPFDCS 1409

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LOXNP_002308.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 64..89 8/24 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 137..174 10/36 (28%)
Lysyl-oxidase like 213..417 38/214 (18%)
Lysyl_oxidase 213..412 CDD:460102 37/211 (18%)
teqNP_648288.2 CBM_14 65..115 CDD:426342
ChtBD2 136..184 CDD:214696
ChtBD2 215..261 CDD:214696
ChtBD2 284..327 CDD:214696
ChtBD2 521..567 CDD:214696
ChtBD2 608..654 CDD:214696
ChtBD2 709..752 CDD:214696
CBM_14 782..829 CDD:426342
ChtBD2 864..909 CDD:214696
CBM_14 942..993 CDD:426342
Med15 1029..>1325 CDD:312941 63/351 (18%)
ChtBD2 1324..1369 CDD:214696 13/44 (30%)
ChtBD2 1474..1518 CDD:214696
PHA03247 <1587..1906 CDD:223021
LDLa 2193..2222 CDD:238060
SR 2229..2331 CDD:214555
LDLa 2337..2370 CDD:197566
SR 2382..2480 CDD:214555
Tryp_SPc 2547..2784 CDD:238113
Blue background indicates that the domain is not in the aligned region.

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