DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment verm and serp

DIOPT Version :9

Sequence 1:	NP_001163469.1	Gene:	verm / 40149	FlyBaseID:	FBgn0261341	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001262062.1	Gene:	serp / 40150	FlyBaseID:	FBgn0260653	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	557	Identity:	315/557 - (56%)
Similarity:	410/557 - (73%)	Gaps:	21/557 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARWWPILSVVCLCLAVDGLYVKNSFEPAIDQDPSRRYQRKPHGQD-KLEGVDVEEVCADRPADE 64
            ||:.:.:.:|:.|.          :|..|...||..||:|:...:: |.|....:|:|.|:.|.|
  Fly     1 MAKLFVVFAVLALA----------AFNEASASDPLLRYKRQATTEETKKEESFEKELCKDKDAGE 55

  Fly    65 YFRLET-DGD-CREVYRCDSAGEDGTWRLAPIRCAGGLAFDVLRQLCDWKSNVKSCDVLEKPRKA 127
            :|||.. :|| ||:|.:|.|:|      |..|||..||.||:.:|.||||.:||:|....|.|:.
  Fly    56 WFRLVAGEGDNCRDVIQCTSSG------LQAIRCPAGLYFDIEKQTCDWKESVKNCKSKNKERRV 114

  Fly   128 KPILKTDEPICPEGKLSCGDGECLDKELFCNGKSDCKDESDENACSVDEDPNRAPECDPTQCALP 192
            ||:|.||||:|.:|.|:||||.|:::.|||||:.||.|.||||.|.:|.||||||.|||..|.||
  Fly   115 KPLLHTDEPLCQDGFLACGDGNCIERGLFCNGEKDCSDGSDENTCDIDNDPNRAPPCDPAVCVLP 179

  Fly   193 DCFCSADGTRIPGGIEPQQVPQMITITFNGAVNVDNIDLYEDIFNGQRQNPNGCSIKGTFFVSHK 257
            |||||.|||.|||.:..:.||.||||||:.|:|.:||:||::||. .|:||||||||.|:|||||
  Fly   180 DCFCSEDGTSIPGDLPAKDVPMMITITFDDAINNNNIELYKEIFK-DRKNPNGCSIKATYFVSHK 243

  Fly   258 YTNYSAVQDLHRRGHEISVFSLTHKDDPNYWTGGSYDDWLAEMAGSRLIVERFANITDGSIIGMR 322
            ||||||||:..|:||||:|.|:||.|:..:|:..:.|||..||||.|:|.|:||||||.|::|:|
  Fly   244 YTNYSAVQETARKGHEIAVHSITHNDEERFWSNATVDDWAKEMAGMRIITEKFANITDNSVVGVR 308

  Fly   323 APYLRVGGNKQFEMMADQFFVYDASITASLGRVPIWPYTLYFRMPHKCNGNAHNCPSRSHPVWEM 387
            |||||||||.||.||.:|.|:||::|||.|...|:||||:||||||:|:||..:||:|||.||||
  Fly   309 APYLRVGGNNQFTMMEEQAFLYDSTITAPLSNPPLWPYTMYFRMPHRCHGNLQSCPTRSHAVWEM 373

  Fly   388 VMNELDRRDDPTFDESLPGCHMVDSCSNVASGDQFARLLRHNFNRHYNSNRAPLGLHFHASWLKS 452
            ||||||||:||..||.||||.|||||||:.:||||...|.|||:|||:.|||||||:|||:|||:
  Fly   374 VMNELDRREDPVNDEYLPGCAMVDSCSNILTGDQFYNFLNHNFDRHYDQNRAPLGLYFHAAWLKN 438

  Fly   453 KKEYRDELIKFIEEML-GRNDVFFVTNLQVIQWMQNPTELNSLRDFQEWKEKCDVKGQPYCSLPN 516
            ..|:.|..:.:|:|:| ..|||:|||..|||||||||..::.:::|:.|:|||.|:|:|.|.:||
  Fly   439 NPEFLDAFLYWIDEILANHNDVYFVTMTQVIQWMQNPRTISEVKNFEPWREKCVVEGKPACWVPN 503

  Fly   517 ACPLTTRELPGETLRLFTCMECPNNYPWILDPTGDGF 553
            .|.||::|:||||:.|.||:.|||||||:.|||||||
  Fly   504 TCKLTSKEVPGETINLQTCVRCPNNYPWVSDPTGDGF 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
verm	NP_001163469.1	CBM_14	57..118	CDD:366726	30/62 (48%)
		LDLa	138..172	CDD:238060	20/33 (61%)
		CE4_CDA_like_1	213..488	CDD:200596	177/275 (64%)
serp	NP_001262062.1	CBM_14	48..105	CDD:279884	30/62 (48%)
		LDLa	125..159	CDD:238060	20/33 (61%)
		CE4_CDA_like_1	200..475	CDD:200596	177/275 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28080
OrthoDB	1	1.010	-	-		D1060206at2759
OrthoFinder	1	1.000	-	-		FOG0003270
OrthoInspector	1	1.000	-	-		otm14253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4295
	7	7.030