DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8765 and madf-9

DIOPT Version :9

Sequence 1:	NP_649141.1	Gene:	CG8765 / 40147	FlyBaseID:	FBgn0036900	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_500389.2	Gene:	madf-9 / 191167	WormBaseID:	WBGene00022608	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	314	Identity:	66/314 - (21%)
Similarity:	117/314 - (37%)	Gaps:	77/314 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QHVNLSIDPSLGENVVSIPK-ELILISLVSQEQSLYNPKHPHYRSTKIKDEKWLEIGSNVGWSDV 82
            :.:|..:..|....:...|. .:.||:.|.....||:.....|.....::..|.||..|:..:..
Worm    29 KEINFLLASSKNMKIEETPVFNIRLIAEVKARPFLYDQSDEGYNLLSWRNSAWNEIAENLETTSE 93

  Fly    83 QCKSKWKAMRDQYCRELKRAKACSKAVKWKYFKELDFLRPYALARNYRGRSGQTSNGAV-----G 142
            ..|::||.:||:|.:|.|:.:...||..|.:.:.|.|::.:...|:........|..||     |
Worm    94 HVKTRWKTLRDRYKKEEKKERVSKKASSWVFQRPLKFIQAHLKDRHTDETDSNQSEPAVKPEPNG 158

  Fly   143 TVTPLSLPMTTSFSSNS---SSQNLNLSGSI-KIEDASASTLLDSCSFSS--------------- 188
            .|:|:...|  ||..|.   :..:...|||. ::|.:||||...:.|..:
Worm   159 HVSPMEAAM--SFIENELIRTQDSSKSSGSTGEMESSSASTASSASSSKNTGTQEGGEASVITPP 221

  Fly   189 ----PSSTDKKPAATFLASHIGAVLQQQQQQQQHQQQMHSQPEANWNYLTDAGGGATPSIIVQCG 249
                |.:....|:||..||:.|..:::.:..                 :|:   |.||.
Worm   222 PLPIPMAVTPSPSATSSASNGGPAVKRSRVS-----------------ITE---GMTPV------ 260

  Fly   250 TANTTTVVDTLYNEIVDCVNAANQSSSAATITSNVSTTSAAHNQSTNAEEEDDD 303
                                |:..:::||..:..:|........:|..|||:|:
Worm   261 --------------------ASRNAAAAAAASLGLSFFPGLSQWATTREEEEDE 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8765	NP_649141.1	MADF	42..123	CDD:214738	23/80 (29%)
CG8765	NP_649141.1	MADF	318..405	CDD:214738
madf-9	NP_500389.2	MADF	52..136	CDD:214738	23/83 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CZ6Y
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810