Protein Alignment tey and rnf220a

DIOPT Version :10

• Sequence 1: NP_001137981.1
• Gene: tey / 40146
• FlyBaseID: FBgn0036899
• Length: 822
• Species: Drosophila melanogaster
• Sequence 2: NP_001430222.1
• Gene: rnf220a / 561654
• ZFINID: ZDB-GENE-060929-1006
• Length: 695
• Species: Danio rerio
• Alignment Length: 774
• Identity: 152/774 - (19%)
• Similarity: 245/774 - (31%)
• Gaps: 280/774 - (36%)

  Fly    55 DLHN--MSLVGNYFNPHLLLNHGMLVANGAAAAAAAAGAGPASYFASDRSPLGKP-SVLSNFSLP 116
            |||.  ..:..:.:.|:.|.:..::|     .|:.|..:..||.......|.|.| ||..:..||
Zfish     2 DLHRAAFKMESSSYLPNPLASPALMV-----LASTAEASRDASIPCQQPRPFGVPVSVEKDVHLP 61

  Fly   117 SAFSPPKYIGISLDQNLFNGSESFRTDSASPTCTSHESMEGSQDYDAVEKGESPRSNNSQD-PRD 180
              |:              |||.:|            .||...|       |..|....::| |..
Zfish    62 --FN--------------NGSYTF------------ASMYHRQ-------GAVPPGFPNRDFPPS 91

  Fly   181 LRHLHNAGKSHQALATSSSASSSSSSSCSTSNPAISTATSSVAVSMASH--LAASSPHHHPHTHA 243
            |.|||     ||        .:..:..||             .:||.:|  :.|..|...|
Zfish    92 LLHLH-----HQ--------FAPPNLDCS-------------PISMLNHSGVGAFRPFASP---- 126

  Fly   244 HSHPHPLAHPHAHSHHHVGHHVGAPPVSTAVTTHHHMAHPHPLSHHHAAHH------AALASLSM 302
                     |........|:.....|...........|.|| |.:..|...      |.:.|.|.
Zfish   127 ---------PEDRDGAGGGYQSAFTPAKRLKGCLEAEASPH-LRYSDAEGKEYDFGGAQIPSSSP 181

  Fly   303 AGLRAVPGG---LSLVSGLQAAAAGGAIPE------------------MCPVCGLKLSAEEWHTH 346
            :.|:||...   :..||||.:.....:.||                  :||:|.:.|...|...|
Zfish   182 SALKAVEDAGKKIFAVSGLLSDRETSSSPEDRIERCKKKVSLYDSQAPICPICQVLLRPGELQEH 246

  Fly   347 FLTELDRL-------------YKLSAGFERASLQATYM-------FAPPCPAQENAIRTSH--NR 389
            ...|::||             ..::.|..::.|.:.::       ...|..:.|     :|  :|
Zfish   247 MEQEMERLTHMHISKNPSHKDINVAPGTPKSLLLSVHIKREGESPVVSPLSSDE-----AHHSDR 306

  Fly   390 WETFQRIRNNRQNRLRLKVRKRKYGEMYMMESLYCSSCPICKRKYALETGKIPPEDDAKSQEEIE 454
            ::||.|:|.|||.||.:.            :..:|       |:||.|:.|.||
Zfish   307 YQTFLRVRANRQTRLNVD------------DLCWC-------RRYAKESFKSPP----------- 341

  Fly   455 TVDVESCNDEVPDSGSELATPSSGSSGTVMPPSSMHNSNSQPGKL------DGILYRTGCVLSQK 513
                             :..|    .|..:.|..:.  :::.||:      ||.:    |.|...
Zfish   342 -----------------IPVP----RGVPLAPCCLR--HARIGKMKRRKPEDGQV----CPLCSA 379

  Fly   514 DPHPDEHDVSTNV----------TTASSSSWPGEAPTQAHISVKTVSELSSTTHHYYNADSCGVG 568
            .....|.::|.:|          |...|:...||..|:                 :...:.||
Zfish   380 PLAGTEEEMSRHVEQCLFKREGATEEDSADVEGENGTR-----------------FEEYEWCG-- 425

  Fly   569 VNDTNSSSSTHNNGGGSNKDLMMDTASCQNDSDEDVIVDDDDTVKLTSKINYGKIQRRQDE---- 629
              .....::|...||.......|.:....:|||.|:.||.|||      :.|||.|..:.:
Zfish   426 --QKRVRATTLLEGGFRGTGFAMCSTKESHDSDADLDVDGDDT------LEYGKAQYTEADIIPC 482

  Fly   630 --QNVGSSRSLE--------------NISPVEERPRSE--PQVSSTEPGPMDISHNNNNNNNNNN 676
              ::.|.::..|              .|:|...:..|:  |..|:.|....:.|.:::::.....
Zfish   483 SGEDQGEAKEREALRGAVLNGGVPSNRITPEFSKWASDEMPSTSNGESSKQEPSSSSSSSTQRTC 547

  Fly   677 NNSNSNNNNNPSTKYA-ESMENSLSQLSSMGVPGLTQLDTKVGISSDLKPDDENKCFIC 734
            .||........||... |:::..:.:|....:.|                 |..||.||
Zfish   548 KNSEIEKITEDSTATTLEALKARIRELEKQILRG-----------------DRYKCLIC 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tey	NP_001137981.1	RNF220	328..>459	CDD:464946	34/170 (20%)
rnf220a	NP_001430222.1	None