DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Oat and BIO3

DIOPT Version :9

Sequence 1:	NP_649139.1	Gene:	Oat / 40145	FlyBaseID:	FBgn0022774	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_014456.1	Gene:	BIO3 / 855795	SGDID:	S000005341	Length:	480	Species:	Saccharomyces cerevisiae

Alignment Length:	457	Identity:	121/457 - (26%)
Similarity:	189/457 - (41%)	Gaps:	111/457 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NKYGAHNYHPLPVALTKGEGVFVWDVEGKRYFDYLSAYSAVNQGHCHPKIVAALTAQASKLALTS 106
            |.|...:.|...:.|.....|   |||   ..|.:|::..|..|:.:|::..|||.|..|
Yeast    34 NVYPVKSAHGCKLVLDTDSPV---DVE---VIDAMSSWWCVIHGYNNPELNEALTKQMLK----- 87

  Fly   107 RAFYSDVLGEYE-----EYVTKLFGFDKVLP---------MNTGVEGGETACKLARKWGYLEKKI 157
              |...:||.:.     ..|.||.   ||:.         .::|....|.|.|:|.: ..:..:.
Yeast    88 --FSHVLLGGFTHKGAVNLVQKLL---KVIDEPSLQYCFLADSGSVAVEVALKMALQ-SNMSGEA 146

  Fly   158 PANQAKIIFARNNFWGRTLSAVSAS----------ND----------PSSYEGFGPFMPGFELIE 202
            ..|:.|.:..:|.:.|.|..|:|..          ||          ||..:|......|||
Yeast   147 TKNRTKFLTIKNGYHGDTFGAMSVCDPENSMHHIYNDRLSENIFAQAPSIVDGLPTSQNGFE--- 208

  Fly   203 YDNVSALEES-------LKDPNVCAFMVEPI-QGEAGVVVPSDGYLKKVRELCTKYNVLWIADEV 259
             |:.:|.|.:       |....:||.::||| ||..|:......:|.:|::||.:|:||:|.||:
Yeast   209 -DHWNAEEVTDLKKQFELHSDKICAVILEPILQGAGGLRPYHPQFLIEVQKLCNQYDVLFIMDEI 272

  Fly   260 QTGLARTGKLLAV---------------DYEQVQPDILILGKALSGGMYPVSAVLCNDQVMLCI- 308
            .||..|||::.|.               |..:|.||||.:||.|:.|...:|||:.||:|...|
Yeast   273 ATGFGRTGEIFAFKHCQKYQDQHGISPSDQIKVVPDILCVGKGLTSGYMTMSAVVVNDKVASRIS 337

  Fly   309 KPGE-------HGSTYGGNPLGCRVAMAALEVL------QEEKLAENAF--KMGDLLRNELSTLP 358
            .|..       ||.|:.||.|.|.||..::::|      ::....||..  ::...::|..:.|.
Yeast   338 SPNSPTGGCFMHGPTFMGNALACSVAEKSMDILLRGEWRKQVSAIENQIYRELYQYIKNPDNGLI 402

  Fly   359 KDVVSVVRGKGLLNAIVINQKFD-AWEVCLRLKENGLLAKPTHGDIIR-------FAPPLVINET 415
            ..||..|...|.:..:.:.:|.| .|      .:...::|..|   ||       ..||.||...
Yeast   403 GTVVKRVSVIGAVGIVELYKKTDPEW------FQKKFISKGVH---IRPFNCLCYIMPPYVITTE 458

  Fly   416 QM 417
            ::
Yeast   459 EL 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oat	NP_649139.1	Orn_aminotrans	34..429	CDD:273853	121/457 (26%)
Oat	NP_649139.1	argD	48..428	CDD:273228	119/451 (26%)
BIO3	NP_014456.1	AAT_I	15..472	CDD:418510	121/457 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4992
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770