DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Oat and Oat

DIOPT Version :9

Sequence 1:	NP_649139.1	Gene:	Oat / 40145	FlyBaseID:	FBgn0022774	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_071966.1	Gene:	Oat / 64313	RGDID:	621724	Length:	439	Species:	Rattus norvegicus

Alignment Length:	440	Identity:	301/440 - (68%)
Similarity:	367/440 - (83%)	Gaps:	12/440 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFAKLSA--------RGIATRMSFLAQKTASQETTAAAGSRSELVYARENKYGAHNYHPLPVALT 57
            |.:||::        ||:.|.:: .|...|:::|.....| ||.::.||:||||||||||||||.
  Rat     1 MLSKLASLQTVAALRRGLRTSVA-SATSVATKKTEQGPPS-SEYIFERESKYGAHNYHPLPVALE 63

  Fly    58 KGEGVFVWDVEGKRYFDYLSAYSAVNQGHCHPKIVAALTAQASKLALTSRAFYSDVLGEYEEYVT 122
            :|:|:::|||||::|||:||||.||:||||||||:.|:.:|..||.|||||||::||||||||:|
  Rat    64 RGKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIEAMKSQVDKLTLTSRAFYNNVLGEYEEYIT 128

  Fly   123 KLFGFDKVLPMNTGVEGGETACKLARKWGYLEKKIPANQAKIIFARNNFWGRTLSAVSASNDPSS 187
            |||.::||||||||||.|||||||||:|||..|.|...:|||:||..|||||||||||:|.||:|
  Rat   129 KLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFAVGNFWGRTLSAVSSSTDPTS 193

  Fly   188 YEGFGPFMPGFELIEYDNVSALEESLKDPNVCAFMVEPIQGEAGVVVPSDGYLKKVRELCTKYNV 252
            |:||||||||||.|.|:::.|||.:|:||||.|||||||||||||:||..|||..||||||::.|
  Rat   194 YDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRHQV 258

  Fly   253 LWIADEVQTGLARTGKLLAVDYEQVQPDILILGKALSGGMYPVSAVLCNDQVMLCIKPGEHGSTY 317
            |:||||:||||||||:.||||:|.|:|||::||||||||:||||||||:|.:||.||||||||||
  Rat   259 LFIADEIQTGLARTGRWLAVDHENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTY 323

  Fly   318 GGNPLGCRVAMAALEVLQEEKLAENAFKMGDLLRNELSTLPKDVVSVVRGKGLLNAIVINQ--KF 380
            ||||||||:|:||||||:||.|||||.|||.:||.||..||.|||:.||||||||||||.:  ..
  Rat   324 GGNPLGCRIAIAALEVLEEEHLAENADKMGAILRKELMKLPSDVVTAVRGKGLLNAIVIRETKDC 388

  Fly   381 DAWEVCLRLKENGLLAKPTHGDIIRFAPPLVINETQMRESIDIIRKTILS 430
            |||:|||||::||||||||||||||.||||||.|.::|||::||.|||||
  Rat   389 DAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRESVEIINKTILS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oat	NP_649139.1	Orn_aminotrans	34..429	CDD:273853	288/396 (73%)
Oat	NP_649139.1	argD	48..428	CDD:273228	278/381 (73%)
Oat	NP_071966.1	Orn_aminotrans	40..437	CDD:273853	289/393 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337496
Domainoid	1	1.000	593	1.000	Domainoid score	I191
eggNOG	1	0.900	-	-		E1_COG4992
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H231
Inparanoid	1	1.050	613	1.000	Inparanoid score	I872
OMA	1	1.010	-	-		QHG63155
OrthoDB	1	1.010	-	-		D145181at2759
OrthoFinder	1	1.000	-	-		FOG0001891
OrthoInspector	1	1.000	-	-		oto97199
orthoMCL	1	0.900	-	-		OOG6_100416
Panther	1	1.100	-	-	LDO	PTHR11986
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1247
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770