DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oat and agxt2

DIOPT Version :9

Sequence 1:	NP_649139.1	Gene:	Oat / 40145	FlyBaseID:	FBgn0022774	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001028922.1	Gene:	agxt2 / 619269	ZFINID:	ZDB-GENE-050913-100	Length:	517	Species:	Danio rerio

Alignment Length:	502	Identity:	128/502 - (25%)
Similarity:	208/502 - (41%)	Gaps:	113/502 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LAQKTASQETTAA---------------AGSRSELVYARENKYGAHNYHPL---------PVALT 57
            |.||||.:..:|.               ..|:..|:..|:     ||.:|:         ||.:.
Zfish    36 LCQKTAVKHPSAVLPQIPPRDFKPEPYQGMSKERLLDIRK-----HNCNPMTMKVTYYKKPVFIN 95

  Fly    58 KGEGVFVWDVEGKRYFDYLSAYSAVNQGHCHPKIVAALTAQASKLALTSRAFYSDVLGEYEEYVT 122
            :|...::|||:|:||.|..:..:.|:.|||:||:..|...|..:|..|:..:   |..:.:||..
Zfish    96 QGHMQWLWDVDGRRYLDLFAGVATVSVGHCNPKVTEAAEKQLRRLWHTTPIY---VYPQIQEYAE 157

  Fly   123 KLFGFDKVLP--------MNTGVEGGETACKLARKWGYLEKKIPANQAKIIFARNNFWGRTLSAV 179
            ||.   .:||        .|:|.|..:.|..:||        :.......|..|.::.|.:..|.
Zfish   158 KLV---SLLPDPLKVVYFTNSGSEANDLAVLMAR--------LHTGNFDAITLRGSYHGGSPQAT 211

  Fly   180 SASND-------PSSYEGFGPFMP-------GFELIEYDNVSALEESLKDPNVC----------- 219
            ...::       |||........|       |........|..:.|....|..|
Zfish   212 GLMSNTHYKYPVPSSLGCHNTMCPDVFRGLWGGSHCRDSPVQTIRECSCSPGHCYANDMYIKELK 276

  Fly   220 ------------AFMVEPIQGEAGVVVPSDGYLKKVRELCTKYNVLWIADEVQTGLARTGK-LLA 271
                        ||..|||||..|.|.....|||:..:|..:...:.||||||||..|||. ...
Zfish   277 EVFDTTVPSRIAAFFTEPIQGVGGAVQYPKNYLKETYQLVREKGGICIADEVQTGFGRTGSHFWG 341

  Fly   272 VDYEQVQPDILILGKALSGGMYPVSAVLCNDQVMLCIKPGEHGSTYGGNPLGCRVAMAALEVLQE 336
            .:...|.||::.:.|.::.|: |:.||:...::......|.|.:|:|||||.|.:|.:.|:.::|
Zfish   342 FEGHNVIPDMVTMAKGIANGI-PMGAVVTTAEIARSFAKGVHFNTFGGNPLACAIASSVLDTIKE 405

  Fly   337 EKLAENAFKMGDLLRNELSTL--PKDVVSVVRGKGL---------------LNAIVINQKF-DAW 383
            :|:.||:.::|..|..||:.|  ..:::..||||||               |....:|:.| |..
Zfish   406 DKMQENSAELGTYLLTELAKLRDKYEIIGDVRGKGLQIGVEMVKDKASRTPLPQEAMNEIFEDTK 470

  Fly   384 EVCLRLKENGLLAKPTHGDIIRFAPPLVINETQMRESIDIIRKTILS 430
            ::.:.:.:.||     :|...|..||:.|.:......:.:..:.:|:
Zfish   471 DMGVLIGKGGL-----YGQTFRIKPPMCITKADADFFLSVFNQAVLN 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oat	NP_649139.1	Orn_aminotrans	34..429	CDD:273853	120/467 (26%)
Oat	NP_649139.1	argD	48..428	CDD:273228	117/452 (26%)
agxt2	NP_001028922.1	GabT	65..510	CDD:223238	121/469 (26%)
agxt2	NP_001028922.1	OAT_like	73..510	CDD:99735	119/461 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145181at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920