Protein Alignment Rnf146 and Rnf146

DIOPT Version :10

• Sequence 1: NP_001137978.1
• Gene: Rnf146 / 40144
• FlyBaseID: FBgn0036897
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_001012060.2
• Gene: Rnf146 / 308051
• RGDID: 1306482
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 304
• Identity: 121/304 - (39%)
• Similarity: 173/304 - (56%)
• Gaps: 34/304 - (11%)

  Fly   106 AAAVSGEDSPSAAAAALECPICLQTCIHPARLPCGHIFCFLCVKGVAYKNRRCAMCRREIPAEFL 170
            |:......:||....  ||.||||||:||..|||.|:||:|||||.::..:|||:||:|||.:||
  Rat    23 ASETCSNTAPSLTVP--ECAICLQTCVHPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFL 85

  Fly   171 DHPQLVNGIEDICTTRATEDGFQWYYEGRNGWWQYDDRTSQDIEDAFKKGDKSCTILVAGYVYIV 235
            |.|.|::..|....:|...: :.|||||||||||||:|||:::||||.||.|:..:|:||::|:.
  Rat    86 DKPTLLSPEELKAASRGNGE-YVWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVA 149

  Fly   236 DLEQLVQQRQNEPTRCRRVKRDLATIPKKGVAGLRIEGNQVTSDTVFSRPTNTANPTTVAAAASS 300
            |||.:||.|:||..|.|::|||:..||||||||||::   ..|:||     |.|..::...|.|.
  Rat   150 DLENMVQYRRNEHGRRRKIKRDIIDIPKKGVAGLRLD---CDSNTV-----NLARESSADGADSG 206

  Fly   301 FISTIAATDAAIRIASDIIGSTLAHAD-ELTRGLTAS-----NLNDD---LSSSGEQSNSTNSND 356
                .|.|.|::::........|...| :||..:|.|     :|.|.   |..||:.....:...
  Rat   207 ----SAHTGASVQLPVPSSTRPLTSVDGQLTSPVTPSPDAGASLEDSFAHLQLSGDSIAERSHRG 267

  Fly   357 AGRSPASSPASSSMQDLITR--------DLRNTQQVIAHNQHTI 392
            .|.....||:|..:.|..|.        |:.:...|:|  ||::
  Rat   268 EGEEDHESPSSGRVPDTSTEETESDASSDIEDAPVVVA--QHSL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf146	NP_001137978.1	RING-HC_RNF146	122..171	CDD:438208	30/48 (63%)
		WWE	192..264	CDD:128922	42/71 (59%)
Rnf146	NP_001012060.2	RING-HC_RNF146	37..86	CDD:438208	29/48 (60%)
		WWE	106..178	CDD:128922	40/71 (56%)