Protein Alignment Rnf146 and Y105E8A.14

DIOPT Version :9

• Sequence 1: NP_001137978.1
• Gene: Rnf146 / 40144
• FlyBaseID: FBgn0036897
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_740943.2
• Gene: Y105E8A.14 / 173308
• WormBaseID: WBGene00013674
• Length: 224
• Species: Caenorhabditis elegans
• Alignment Length: 190
• Identity: 57/190 - (30%)
• Similarity: 82/190 - (43%)
• Gaps: 43/190 - (22%)

  Fly   123 ECPICLQTCIHPARLP-CGHIFCFLCVKGVAYKNR-RCAMCRREIPAEFLDHP-QLVNGIEDICT 184
            ||.:|....|.|..:| |||.|||:|:|||:..|. .|.:||..|.::....| |.|:...||..
 Worm    23 ECAVCYSEMILPTTIPSCGHKFCFICLKGVSVSNNGDCPICRGPIDSQIFKKPLQAVDLKMDIPG 87

  Fly   185 T-----------------------------------RATEDGFQWYYEGRN-GWWQYDDRTSQDI 213
            |                                   .|......|.|.||: |||::|.|..::|
 Worm    88 TPSAAAPDPVVKQEVDDEDVKPDVKKLQEELKKQQAAAAAQKMFWLYRGRHQGWWRFDPRIEKEI 152

  Fly   214 EDAFKKGDKSCTILVAGYVYIVDLEQLVQQRQNEPTRCRRVKR----DLATIPKKGVAGL 269
            |:||........:.:.|..||||..|:.|..:|:....|.|||    |..::..||::|:
 Worm   153 EEAFTHQMPMTEVTICGNPYIVDFSQMCQYPKNQSNYSRNVKRVNSTDFDSLNVKGMSGV 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf146	NP_001137978.1	RING	123..165	CDD:238093	20/43 (47%)
		WWE	192..264	CDD:128922	26/76 (34%)
Y105E8A.14	NP_740943.2	RING	23..67	CDD:238093	20/43 (47%)
		WWE	130..202	CDD:128922	26/71 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159499
Domainoid	1	1.000	62	1.000	Domainoid score	I6840
eggNOG	1	0.900	-	-		E1_KOG0824
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5209
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004614
OrthoInspector	1	1.000	-	-		otm14634
orthoMCL	1	0.900	-	-		OOG6_107506
Panther	1	1.100	-	-	LDO	PTHR13417
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2954
SonicParanoid	1	1.000	-	-		X3820
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.680