DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wnd and AT5G11850

DIOPT Version :9

Sequence 1:	NP_649137.3	Gene:	wnd / 40143	FlyBaseID:	FBgn0036896	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_196746.2	Gene:	AT5G11850 / 831058	AraportID:	AT5G11850	Length:	880	Species:	Arabidopsis thaliana

Alignment Length:	439	Identity:	131/439 - (29%)
Similarity:	209/439 - (47%)	Gaps:	58/439 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQPFS-----------DSLSKSRDDLVTAASRQQ--QQLHGRRRHHGSS--PNLSLDQTDNLRRS 50
            |.|||           .::||.   :::||...:  |:||......|:|  |:|.:|...:..|.
plant   442 MPPFSGKPTCAQKVKVKNVSKY---VISAAKNPEFAQKLHAVLLESGASPPPDLFMDINPHNLRG 503

  Fly    51 MACLQD---EFGHLGIAATDLPFKSSDLDSPPRLQHHNNYAEITDSSAENTCQQRWPPHVGGAGA 112
            ...||:   |..:..::.  :|.....:....|....|..||....|.|.....:....:...|.
plant   504 KNLLQELRQESSNSMVSG--IPCYPEKVAEQLRESERNPTAESYQQSVEVDLSMKRNFDLDNTGK 566

  Fly   113 AFGHPDKPIGWMYGLLGCMKPVLSFIGKTGVIEVKSQ-------RSEDWQIPFESITELEWLGSG 170
            |....:..:|             :..|::.|.:...|       .:..|:|.:|.:...|.:|.|
plant   567 ASSSENMEVG-------------TADGESAVCDSHDQGINPLLGEAAKWEIMWEDLQIGERIGIG 618

  Fly   171 AQGAVFSGRLKNETVAVKKVKELK---------ETDIKHLRKLDHENIIKFKGVCTQSPVFCIIM 226
            :.|.|:........|||||..:..         :::|:.:.:|.|.|::.|.|..|:.|.|.|:.
plant   619 SYGEVYRAEWNGTEVAVKKFLDQDFSGDALTQFKSEIEIMLRLRHPNVVLFMGAVTRPPNFSILT 683

  Fly   227 EFCPYGPLQNILKEEQVML-PSRLVSWSKQIALGMQYLH-SH-KIIHRDLKSPNILISTNEVVKI 288
            ||.|.|.|..:|......| ..|.:..:..:|.||.||| || .::||||||||:|:..|.|||:
plant   684 EFLPRGSLYRLLHRPNHQLDEKRRMRMALDVAKGMNYLHTSHPTVVHRDLKSPNLLVDKNWVVKV 748

  Fly   289 SDFGTSR--EWNEISTKMSFAGTVAWMAPEVIRNEPCSEKVDIWSYGVVLWEMLTCEIPYKDVDS 351
            .|||.||  ....:|:| |.|||..||||||:||||.:||.|::|:||:|||:.|..:|:|.::.
plant   749 CDFGLSRMKHHTYLSSK-STAGTPEWMAPEVLRNEPANEKCDVYSFGVILWELATSRVPWKGLNP 812

  Fly   352 SAIIWGVGNNSLKLLVPSTCPEGFKLLVKLCWKSKPRNRPSFRQILSHL 400
            ..::..||..:.:|.:|.........:::.||:::|..||||.|::..|
plant   813 MQVVGAVGFQNRRLEIPDDIDLTVAQIIRECWQTEPHLRPSFTQLMQSL 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STYKc	161..400	CDD:214568	94/252 (37%)
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	94/248 (38%)
AT5G11850	NP_196746.2	EDR1	140..344	CDD:291079
		Pkinase_Tyr	609..861	CDD:285015	94/252 (37%)
		STKc_MAP3K-like	615..861	CDD:270901	93/246 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	173	1.000	Domainoid score	I1116
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1208
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23257
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X966
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.010