Protein Alignment wnd and Map3k9

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_038968663.1
• Gene: Map3k9 / 500690
• RGDID: 1562149
• Length: 1120
• Species: Rattus norvegicus
• Alignment Length: 939
• Identity: 242/939 - (25%)
• Similarity: 359/939 - (38%)
• Gaps: 254/939 - (27%)

  Fly   155 QIPFESITELEWLGSGAQGAVFSGRLKNETVAVKKVKELKETDI-----------KHLRKLDHEN 208
            :|.|..:|..|.:|.|..|.|:......:.||||..:...:.||           |....|.|.|
  Rat   131 EIDFAELTLEEIIGIGGFGKVYRAFWVGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPN 195

  Fly   209 IIKFKGVCTQSPVFCIIMEFCPYGPLQNILKEEQVMLPSRLVSWSKQIALGMQYLHSHKI---IH 270
            ||..:|||.:.|..|::|||...|||..:|..::|. |..||:|:.|||.||.|||...|   ||
  Rat   196 IIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRVP-PDILVNWAVQIARGMNYLHDEAIVPVIH 259

  Fly   271 RDLKSPN--------------------ILI--------STNEVVKISDFGTSREWNEISTKMSFA 307
            |||||.|                    :||        .:|:.:||:|||.:|||:. :||||.|
  Rat   260 RDLKSSNSECGELGWGEQHSLSLRLCEVLILQKVENGDLSNKTLKITDFGLAREWHR-TTKMSAA 323

  Fly   308 GTVAWMAPEVIRNEPCSEKVDIWSYGVVLWEMLTCEIPYKDVDSSAIIWGVGNNSLKLLVPSTCP 372
            ||.|||||||||....|:..|:|||||:|||:||.|:|::.:|..|:.:||..|.|.|.:|||||
  Rat   324 GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCP 388

  Fly   373 EGFKLLVKLCWKSKPRNRPSFRQILSHLDIAGPELLRKTEKQYFE--------TQKSWKEEVRSH 429
            |.|..|::.||...|.:||||..||.       :|....|..:||        .|..||.|::..
  Rat   389 EPFAKLMEDCWNPDPHSRPSFSSILD-------QLTTIEESGFFEMPKDSFHCLQDDWKHEIQEM 446

  Fly   430 LKEITQNGTNIHKYEQDLIKRRTAEWRHAQDIRMVYEDKLQKTNQLFFELSECMSQLQEKEKEIA 494
            ..::......:..:|::|.:.                 .||:.||  .||      |:.:|:|:|
  Rat   447 FDQLRAKEKELRTWEEELTRA-----------------ALQQKNQ--EEL------LRRREQELA 486

  Fly   495 ERERKLPGSGYKPNRRFGNTIRKMQHYRRRLNPAPAAIQQQSTTPDPETTPESPVKCMLYAQLDS 559
            |||                    :....|.||                         ::..||
  Rat   487 ERE--------------------IDILERELN-------------------------IIIHQL-- 504

  Fly   560 NCQPKSYLANIIPSSGLGAPMPNKNKKVFRHRR---NASGSFGAPPKY--------SPTRDRR-- 611
             ||.|              |...|.|..||..|   ........|..:        |||.|:|
  Rat   505 -CQEK--------------PRVKKRKGKFRKSRLKLKDGNRISLPSDFQHKFTVQASPTMDKRKS 554

  Fly   612 ----YQSEPEN-------RKVQLVERQTQTDAMDVSETDISPSAEAPRSQPIDVPVPNHRQLPLQ 665
                ..|.|.:       |.:||...::   :.....:.:.|..|....:         ::.|.:
  Rat   555 LISNRSSPPASPTIIPRLRAIQLTPGES---SKTWGRSSVVPKEEGEEEE---------KRAPKK 607

  Fly   666 LQRVQKIAQ-AQARARSGSTSSAAGAVNPACPSNGNSLSTSELT-------------YQDACSSP 716
            ..|...... .|....||...|      |......|.|||...:             |:...||.
  Rat   608 KGRTWGPGTLGQKELTSGDEGS------PQRREKANGLSTPSESPHFHLGLKSLVDGYKQWSSSA 666

  Fly   717 DQLIDDVMNSNERLDMTECCS-DNENLERLGRKVIEFINENRLSIQSNTNSV----SNADNGNGG 776
            ..|.....:|......|.... ::|:.|..|.      .||.|....|.:.:    ...::|:|.
  Rat   667 PNLGKGPRSSPALPGFTSLMEIEDEDSEGPGS------GENHLQHSPNQSYLCIPFPRGEDGDGP 725

  Fly   777 AS------PLELRESGNSPCLS-----RCSSTHSKRRKHPL---GDNPNGSSIGNANGESHEQDS 827
            :|      |..:..:.::|.|:     :.|.||.:|.:..|   |.....:.:|....|:.:...
  Rat   726 SSDGIHEEPTPVNSATSTPQLTPTNSLKRSGTHHRRCEVALLGCGAVLAATGLGFDLLEAGKCQL 790

  Fly   828 WSDEEGETTDYKYALRRRSIGRQPIARGMRPRRSYKAPLSQKIAIHKRNVVIVSDEEENTSEYSH 892
            ...||.|....:...||..:    ..|..||||| .:|.|:|:...:..:.::.|...:.:..|.
  Rat   791 LPPEEPEPPAREEKKRREGL----FQRASRPRRS-TSPPSRKLFKKEEPMTLLGDPSASLTLLSL 850

  Fly   893 SP----SSQHSTLESNTD--------IADMKKTQATSTSSNSYSEPEDDSSDSSDEEQGNRPTEA 945
            |.    :|..|.|.|::|        ::.::....|..:.|.......:.. ..|..|...||..
  Rat   851 SSISECNSTRSLLRSDSDEIVVYEMPVSPVEAPPLTQCTQNPLVNVRVERF-KRDPNQSLTPTHV 914

  Fly   946 KAEGPALPMGAVRSSDIISIPTFEADGAV 974
            ....|..|.|..|:         .:|||:
  Rat   915 TLTAPTQPSGHRRT---------PSDGAL 934

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	115/277 (42%)
Map3k9	XP_038968663.1	SH3_MLK1-3	49..106	CDD:212992
		STKc_MLK1	130..419	CDD:271047	120/296 (41%)