Protein Alignment wnd and MOS

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_005363.1
• Gene: MOS / 4342
• HGNCID: 7199
• Length: 346
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 85/298 - (28%)
• Similarity: 136/298 - (45%)
• Gaps: 47/298 - (15%)

  Fly   151 SEDWQIPFESITELEWLGSGAQGAVFSGRLKNETVAVKKVKELKETDIKHLR---------KLDH 206
            |.||    |.:..|:.||:|..|:|:....:...||:|:|.:..:..:...|         :|.|
Human    54 SIDW----EQVCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRH 114

  Fly   207 ENIIKFKGVCTQSP-----VFCIIMEFCPYGPLQNIL-----------------KEEQVMLPSRL 249
            :||::.....|::|     :..|||||.....|..::                 ...|:.| .:.
Human   115 DNIVRVVAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPEGDAGEPHCRTGGQLSL-GKC 178

  Fly   250 VSWSKQIALGMQYLHSHKIIHRDLKSPNILISTNEVVKISDFGTSREWNEI----STKMSFAGTV 310
            :.:|..:..|:.:|||..|:|.|||..|||||..:|.||||||.|.:..::    :......||.
Human   179 LKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTY 243

  Fly   311 AWMAPEVIRNEPCSEKVDIWSYGVVLWEMLTCEIPYKDVDSSAIIWGVG----NNSLKLLVPSTC 371
            ...|||:::.|..:.|.||:|:.:.||:|.|.:.||.. :...|::.|.    ..||...|....
Human   244 THRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSG-ERQHILYAVVAYDLRPSLSAAVFEDS 307

  Fly   372 PEGFKL--LVKLCWKSKPRNRPSFRQILSHLDIAGPEL 407
            ..|.:|  :::.||:.....|||.|.:|..|.....||
Human   308 LPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTSLKAEL 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	78/276 (28%)
MOS	NP_005363.1	STKc_Mos	56..338	CDD:270881	81/287 (28%)