Protein Alignment wnd and Src

DIOPT Version :9

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_006499126.1
• Gene: Src / 20779
• MGIID: 98397
• Length: 552
• Species: Mus musculus
• Alignment Length: 561
• Identity: 131/561 - (23%)
• Similarity: 205/561 - (36%)
• Gaps: 174/561 - (31%)

  Fly     9 SKSRDDLVTAASRQQQQLHGRRRHHGSSPNLSLDQTDNLRRSMACLQDEFGHLGIAATDLP---- 69
            ||.:|     ||::::.|......||:.......||.:...|..      ||.|.:|..:|
Mouse     6 SKPKD-----ASQRRRSLEPSENVHGAGGAFPASQTPSKPASAD------GHRGPSAAFVPPAAE 59

  Fly    70 ------FKSSDLDSPP---------------------------------RLQHHNNYAEITDSSA 95
                  |.|||..:.|                                 |||..||..::..|..
Mouse    60 PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKVDVSQT 124

  Fly    96 ENTCQ--QR----WPPHVGGAGAAFGHPDKPIG---------WMYG----------LLGCMKPVL 135
            ..|.:  ||    |..|....|.....|...:.         |.:|          ||....|..
Mouse   125 WFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRG 189

  Fly   136 SFIGK------------------------------------------------------------ 140
            :|:.:
Mouse   190 TFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHAD 254

  Fly   141 -----------TGVIEVKSQRSEDWQIPFESITELEWLGSGAQGAVFSGRLKNET-VAVKKVKE- 192
                       |...:.:....:.|:||.||:.....||.|..|.|:.|.....| ||:|.:|.
Mouse   255 GLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG 319

  Fly   193 -------LKETDIKHLRKLDHENIIKFKGVCTQSPVFCIIMEFCPYGPLQNILKEE---QVMLPS 247
                   |:|..:  ::||.||.:::...|.::.|:: |:.|:...|.|.:.||.|   .:.||
Mouse   320 TMSPEAFLQEAQV--MKKLRHEKLVQLYAVVSEEPIY-IVTEYMNKGSLLDFLKGETGKYLRLP- 380

  Fly   248 RLVSWSKQIALGMQYLHSHKIIHRDLKSPNILISTNEVVKISDFGTSR--EWNEISTKMSFAGTV 310
            :||..|.|||.||.|:.....:||||::.|||:..|.|.|::|||.:|  |.||.:.:......:
Mouse   381 QLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPI 445

  Fly   311 AWMAPEVIRNEPCSEKVDIWSYGVVLWEMLT-CEIPYKDVDSSAIIWGVGNNSLKLLVPSTCPEG 374
            .|.|||.......:.|.|:||:|::|.|:.| ..:||..:.:..::..| ....::..|..|||.
Mouse   446 KWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQV-ERGYRMPCPPECPES 509

  Fly   375 FKLLVKLCWKSKPRNRPSFRQILSHLDIAGPELLRKTEKQY 415
            ...|:..||:.:|..||:|..:.:.|:    :....||.||
Mouse   510 LHDLMCQCWRKEPEERPTFEYLQAFLE----DYFTSTEPQY 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STYKc	161..400	CDD:214568	80/253 (32%)
		STKc_MAP3K12_13	167..403	CDD:270961	81/250 (32%)
Src	XP_006499126.1	SH3_Src	87..159	CDD:212941	13/71 (18%)
		SH2_Src_Src	163..263	CDD:198228	6/99 (6%)
		PTKc_Src	276..552	CDD:270656	90/280 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910