Protein Alignment wnd and sid-3

DIOPT Version :9

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_510783.2
• Gene: sid-3 / 181756
• WormBaseID: WBGene00002207
• Length: 1237
• Species: Caenorhabditis elegans
• Alignment Length: 1118
• Identity: 233/1118 - (20%)
• Similarity: 367/1118 - (32%)
• Gaps: 383/1118 - (34%)

  Fly   148 SQRSEDWQ--IPFESITELEWLGSGAQGAVFSG--RLKNET---VAVKKVKELK-------ETDI 198
            :|.|.|.:  ||.|.|...|.:|.|:...|..|  ...|.|   ||||.::::.       ..:.
 Worm    92 AQNSIDEKALIPNEQIKLYELIGEGSFAVVKRGTWTQSNGTHVNVAVKILRDISPNIMDDLRVEA 156

  Fly   199 KHLRKLDHENIIKFKGVCTQSPVFCIIMEFCPYGPLQNILKEEQ--VMLPSRLVSWSKQIALGMQ 261
            .||.||.|.::|:..|:..|..:  ::.|.|..|.|.:.|::::  ::|.|||..:..|||..:|
 Worm   157 SHLLKLQHPSLIRLYGIVRQPAM--MVFELCEGGSLLDRLRDDKKAILLVSRLHDYCMQIAKALQ 219

  Fly   262 YLHSHKIIHRDLKSPNILISTNE-VVKISDFGTSREWNEISTKMSFAG----TVAWMAPEVIRNE 321
            :|.|...:|||:.:.|||::.:| .|||.|||..|...|.....:.|.    ..||..||.:|:.
 Worm   220 FLESKHCVHRDVAARNILLARDERTVKICDFGLMRALKENEQMYTMAPQKKVPFAWCPPEALRHR 284

  Fly   322 PCSEKVDIWSYGVVLWEMLTC-EIPY---------KDVDSSAIIWGVGNNSLKLLVPSTCPEGFK 376
            ..|...|:|||||.:||:.|. |.|:         |::|:..          :|..|..|.|...
 Worm   285 KFSHASDVWSYGVTIWEVFTFGEEPWVGCRAIDVLKNIDAGE----------RLEKPKYCSERIY 339

  Fly   377 LLVKLCWKSKPRNRPSFRQILSHLDIA-----------------------GPE--LLRKTEKQYF 416
            .::|.|||..|..|..|..|...|..|                       |.|  ::..|.:.:|
 Worm   340 QIMKNCWKFNPAERCKFGAIREDLVAAMFLDAVARETYNSIQPGALQLTKGDEVVVVENTGQDWF 404

  Fly   417 -ETQKSWK-------------------------------EEVR---SH-----LKEITQN----- 436
             :.:|:.|                               ..:|   ||     ||.:..|
 Worm   405 GQNKKNQKFGTFPRSVVFAQTNNAVAAATAVTPQKVPTAPTIRIPPSHPPPAPLKPLNNNTKTSL 469

  Fly   437 ------------GTNIHKYEQDLIKRRTAEWRHAQDIRMVY----------------------ED 467
                        |:.||....|.:..::  |.:...|..:|                      ::
 Worm   470 NDRTSKISMPVAGSFIHTGHGDPLGGQS--WGNPATIADMYLKNPVNGAPLSSMSSGAEIIASKE 532

  Fly   468 KL----QKTNQLFFELSECMSQLQEKEKEIAERE--RKLPGSGYKPN-----RRF---------- 511
            .|    :.|:|........||:::....::.|.:  .:....|:.|:     |.|
 Worm   533 LLTNGGRSTHQPAAPSPAVMSKIRGLSLDLPEYDDFDRAFDDGFSPSKIELPREFCGNDSVISGG 597

  Fly   512 GNTIRKMQHY-------------RRRL------------NPAPAAI--------------QQQST 537
            .|:|.....|             .|.|            ||||:.|              .|..|
 Worm   598 SNSIGLANTYVMEPPKQAFDIRGNRVLPPTNKAPVLIPTNPAPSVISSTASAGITLSTNSSQMFT 662

  Fly   538 TPDPETTPESPVKCMLYAQLDSNCQPKSYLANII---PSSGLGA---------PMPNK-----NK 585
            :.|    ..|.:...|:.:|.......|...|.:   |:|.:|.         |..|:     |.
 Worm   663 SQD----RHSNMPANLFPELQHRLNQGSSTGNGVRPRPASSIGIQNNDLSMLNPQVNRPFSVVNV 723

  Fly   586 KVFRHRRN-----ASGSFGAPPKYS-PTRDRRYQSEPENR---------KVQLVERQTQTDA--- 632
            .:.:...|     .:.:..||..:| |...:|...:.:|.         |..|.:|.|.|.|
 Worm   724 PIVQQPANIPCLVPTPAPPAPAHFSQPVSSQRVAQQQQNTLQKALNDELKGNLNKRPTGTTAPPS 788

  Fly   633 --MDVSETDISP-------SAEAPRSQPIDVPVPNHRQLPLQLQR---------VQKIAQAQARA 679
              .:....|::|       ||..|..||..:   .|.|.|:|.|:         |||..|..|..
 Worm   789 NGFNAPRADVAPVQQRPISSASIPALQPQPI---QHIQKPIQPQQVRIPPSTAPVQKPVQVSAPT 850

  Fly   680 RSG-----STSSAAGAVNPACPSNGNSLSTSELTYQDACSSPDQLIDDVMNSNER-LDMTECCSD 738
            .|.     |:.::|.|.||..|.....:|.:.:|.....::|............| ...|...||
 Worm   851 HSNVAPTTSSQASADARNPLPPKTSPPVSNTPITVAPVHAAPTTSAPSTSVVTRRPTSTTAQMSD 915

  Fly   739 NENLERLGRKVIEFINENRLSIQSNTNSVSNADNGNGGASPLELRESGNSPCLSRCSSTHSKRRK 803
            .|...|:.           :.|.|...:.|....|:...|.|.      |..:|..||..|..|.
 Worm   916 EERRSRIA-----------MDISSALPAPSALLYGSNSTSSLP------SAAVSTASSVPSTARD 963

  Fly   804 HPLGDNPNGSSIGNANGESHEQDSWSDEEGETTDYKYALRRRSIGRQPIARGMRPRRSYKAPLSQ 868
            :|:...|:                                      ||... |.|::|.:..||.
 Worm   964 NPVETRPS--------------------------------------QPHVT-MPPKKSSEPILSS 989

  Fly   869 KIAIHKRNVVIVSDEEENTSEYSHSPSSQHSTLESNTDIADMKKTQAT----------STSSNSY 923
            ::....|.....:.:.:..::....||...:|: ..|.:.|.|.....          :.|||.|
 Worm   990 EVLQPTRLPSATTSQAKPVTQPIRHPSPPVATV-IPTAVVDKKPVSQNQGSNVPLFNITNSSNGY 1053

  Fly   924 SE------------------------PEDDSSDSSDEEQGNR--------------PTEAKAEGP 950
            .:                        |.....:|.....|..              |:|.:..|.
 Worm  1054 PQLNGYPNYGNGFQAYGYGMNYHQGYPGYQGYNSYGNGMGQLALTHNAVTSLPPLVPSENRFSGT 1118

  Fly   951 ALPMGAVRSSDII 963
            |.|:|   .|||:
 Worm  1119 AQPLG---ESDIM 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STYKc	161..400	CDD:214568	82/267 (31%)
		STKc_MAP3K12_13	167..403	CDD:270961	81/264 (31%)
sid-3	NP_510783.2	SAM_TNK-like	9..70	CDD:188938
		STYKc	107..363	CDD:214568	82/267 (31%)
		PTKc_Ack_like	111..365	CDD:270636	82/265 (31%)
		SH3	371..421	CDD:214620	6/49 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I3014
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960