Protein Alignment wnd and kin-26

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_501309.1
• Gene: kin-26 / 177575
• WormBaseID: WBGene00002208
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 320
• Identity: 96/320 - (30%)
• Similarity: 153/320 - (47%)
• Gaps: 31/320 - (9%)

  Fly   140 KTGVIEVKSQRSEDWQIPFESITELEWLGSGAQGAVFSG------RLKNETVAVKKVK------- 191
            |.|.:.|...|.:.|::..:.||..:.||.||.|.|.||      .:|...||:|:||
 Worm   109 KEGCMLVNPIRRQFWELEHDQITIHKKLGEGAFGEVSSGVMKFKKGMKTVQVAIKQVKLDKTGKA 173

  Fly   192 ELKE--TDIKHLRKLDHENIIKFKGV-CTQSPVFCIIMEFCPYGPLQNILKEEQVMLPSRLVSWS 253
            ::|:  .:.:.:|||.|:|||||.|| ..|.|:: ::||....|.|.:.||:.:.:...:.....
 Worm   174 KIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLY-LVMELAVNGALDSFLKKNEDLSVDKKTEMI 237

  Fly   254 KQIALGMQYLHSHKIIHRDLKSPNILISTNEVVKISDFGTSREWNEISTKMSFAGTVAWMAPEVI 318
            .|.|.|::|:|...::|||:.:.|.|. |:..|||||||.:|.......|.:....:.|:|.|.|
 Worm   238 LQAAWGLEYIHGKPMLHRDIAARNCLY-TDGKVKISDFGLTRNGTVYQIKPNTKSPIRWLAIETI 301

  Fly   319 RNEPCSEKVDIWSYGVVLWEML-TCEIPYKDVDSSAIIWGVGNNSLKLLVPSTCPEGFKLLVKLC 382
            :...||||.|:|:|||:.||:. ....||..:..:.:...|.|.......|....| .:.::..|
 Worm   302 KTMICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAE-IQTMMARC 365

  Fly   383 WKSKPRNRPSFRQILSHL----DIAGPELLRKTEKQYFE-------TQKSWKEEVRSHLK 431
            ....|.:|||..:|...|    :...|......:|:..|       |.|:.....:|::|
 Worm   366 NAENPNDRPSMAEIAEILQRVTETPRPNFTAIAKKEAEELLLMNSVTTKTTARRKKSNVK 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	82/256 (32%)
kin-26	NP_501309.1	SH2_Fps_family	15..108	CDD:198224
		TyrKc	130..383	CDD:197581	83/255 (33%)