Protein Alignment wnd and R05H5.4

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_496201.1
• Gene: R05H5.4 / 174581
• WormBaseID: WBGene00011039
• Length: 414
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 82/299 - (27%)
• Similarity: 146/299 - (48%)
• Gaps: 36/299 - (12%)

  Fly   140 KTGVIEVKSQR--------SEDWQIPFESITELEWLGSGAQGAVFSGRL--KNETVAVKKV---- 190
            |...||::.::        ...:|:..:.:...:.:|:||.|.|:.|:|  .:|.:||||:
 Worm    91 KADPIEIRGEKVVLKRAIPKGKFQLMHKDVIFQKKIGAGAYGTVYRGKLVKTDEVIAVKKLDPEG 155

  Fly   191 -------KELKETDIKHLRKLDHENIIKFKGVCTQSPVFCIIMEFCPYGPLQNILKE--EQVMLP 246
                   :.:||..:..|  .||.||:||.|.......:.:::|:|..|.:::.|::  |::.:|
 Worm   156 ADEDGLAEMMKEARVMQL--YDHPNIVKFHGFILDDLPYLLVLEYCNGGAVEDRLRDKGEKIKVP 218

  Fly   247 SRLVSWSKQIALGMQYLHSHKIIHRDLKSPNILISTNEVVKISDFGTSREWNEISTKMSFAGTVA 311
            :| |.::...|.||.|||....||||:.|.|.||... |||::|||..|..:.....:.....:.
 Worm   219 TR-VKYTYMAACGMDYLHKKNCIHRDIASRNCLIHKG-VVKMADFGMCRAQSVYKVDLKKPCNIR 281

  Fly   312 WMAPEVIRNEPCSEKVDIWSYGVVLWEMLTCEIPYKD--VD-SSAIIWGVGNNSLKLLVPSTCPE 373
            |:||||..|.......|::::|:::||..  |.|:|.  |: .:|.:........:|..|.:.|.
 Worm   282 WLAPEVWDNGETRFNTDVYAFGIMMWEFF--ETPFKSPYVEMKAAQVKRKTRAGYRLPPPPSMPS 344

  Fly   374 GFKLLVKLCWKSKPRNRPSFRQILSHLDIAGPELLRKTE 412
            ....::..||:.....||:..::...|:    |..:|||
 Worm   345 RMVEIMSECWQVDAEKRPTAEELKEKLE----EFKKKTE 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	74/253 (29%)
R05H5.4	NP_496201.1	SH2_Fps_family	9..97	CDD:198224	2/5 (40%)
		TyrKc	120..363	CDD:197581	72/248 (29%)