Protein Alignment wnd and mom-4

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_492620.1
• Gene: mom-4 / 172842
• WormBaseID: WBGene00003396
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 115/539 - (21%)
• Similarity: 205/539 - (38%)
• Gaps: 139/539 - (25%)

  Fly   155 QIPFESITEL--EWLGSGAQGAVFSGRLKN------ETVAVKKVKELKETDIKHLRKL-----DH 206
            :|..:.|..|  .:||.|..|.|...|.:.      ...|:|...:|....:....|:     :|
 Worm    43 EIQAQCIDNLNSHYLGKGTYGLVEKTRYRKTRQDDFRPAAIKYSSQLHMATLIREAKVMWDLRNH 107

  Fly   207 ENIIKFKGVCTQSP--VFCIIMEFCPYGPLQNILKEEQVM--LPSRLVSWSKQIALGMQYLHSHK 267
            .||||..|: .:||  ...::||:...|.:.::|.:...:  ....:.||..|::..:.:.||:.
 Worm   108 PNIIKIYGL-YKSPRNGQGVVMEYMDCGSMADLLYDRTHINYTIDHVASWMFQLSSAVDFFHSNS 171

  Fly   268 IIHRDLKSPNILISTN-EVVKISDFGTSREWNEISTKMSFAGTVAWMAPEVIRNEPCSEKVDIWS 331
            .:|||||..|:|:|.. ..:|:.||||....::..|  |..||...|||||.|.|..:.|.||:|
 Worm   172 QVHRDLKLQNMLLSDRYRTMKLCDFGTFTSMHQSMT--SNRGTPITMAPEVFRCEQYNMKSDIYS 234

  Fly   332 YGVVLWEMLTCEIPY-KDVDSSAIIWGVGNNSLKLLVPS--TCPEGFKLLVKLCWKSKPRNRPSF 393
            .|:::|:::....|| :|:....:::.|...:|:   |.  .|........|.||......||:.
 Worm   235 IGIIMWQIIARNHPYRRDLSVPGLLYNVATANLR---PQELECNPILSEFYKKCWNDNADIRPTS 296

  Fly   394 RQILSHLDIAGPELLRKTEKQYFETQKSWKEEVRSHLKEITQNGTN-------IHKYEQDLI--- 448
            .:.:.:..:.                   |:|..:....::.:.||       .|.:...::
 Worm   297 SECVEYFTLL-------------------KDEYPNGSVPLSDSSTNGPAETPPPHAHRPTMLGTS 342

  Fly   449 -------KRRT--------------AEWRHAQDIRMVYED-------------KLQKTNQLFFEL 479
                   ..||              ...|:..:..:|..|             ::.|
 Worm   343 SGSGIGSNNRTPTASKLLNPQQPGQGHRRNRSETFVVQPDLPYPTVPGEAGASRIPK-------- 399

  Fly   480 SECMSQLQEKE-KEIAERERKLPGSGYKPNRRFGNTIRKMQHYRRRLNPAPAAI-----QQQSTT 538
                ||.:.|. ::.|:.|::.|....:|...|       :|.|...:....|:     ..:.|.
 Worm   400 ----SQSEAKNFRDRAKSEQRQPHRDARPPPPF-------EHRRDSNDEEKHAVFMNICSNEETR 453

  Fly   539 P-DPETTPESPVKCMLYAQLDSNCQPKSYL-ANIIPSSGLGAPMPNKNKKVFRHRRNASGSFGAP 601
            | ||:|..|..:: :.:...|:|   |.|. |.:|            .|:|.|.:......:
 Worm   454 PIDPDTRDEKSLE-IFHQHCDNN---KQYADAWVI------------KKEVMRAKHELIAQW--- 499

  Fly   602 PKYSPT---RDRRYQSEPE 617
            |::..|   .:|:|..|.|
 Worm   500 PQHDHTVELLERKYYLEQE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	69/254 (27%)
mom-4	NP_492620.1	Protein Kinases, catalytic domain	57..303	CDD:473864	69/251 (27%)