Protein Alignment wnd and hck

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_005174178.1
• Gene: hck / 101885596
• ZFINID: ZDB-GENE-090313-72
• Length: 499
• Species: Danio rerio
• Alignment Length: 286
• Identity: 92/286 - (32%)
• Similarity: 149/286 - (52%)
• Gaps: 27/286 - (9%)

  Fly   147 KSQRSEDWQIPFESITELEWLGSGAQGAVFSGRLKNET-VAVKKVKE--------LKETDIKHLR 202
            |....:.|:||.||:...:.||:|..|.|:.......| ||||.:|.        |.|.::  ::
Zfish   220 KPWEKDAWEIPRESLKLDKRLGAGQFGEVWMAMYNKHTKVAVKTMKPGSMSVEAFLMEANL--MK 282

  Fly   203 KLDHENIIKFKGVCTQSPVFCIIMEFCPYGPLQNILKEEQ---VMLPSRLVSWSKQIALGMQYLH 264
            .|.|:.:::...|.|:.....||.||...|.|.:.:|.::   |.|| :|:.:|.|||.||.|:.
Zfish   283 SLQHDKLVRLNAVVTKEEPIYIITEFMEKGSLLDFIKSDEGNRVQLP-KLIDFSAQIAEGMAYIE 346

  Fly   265 SHKIIHRDLKSPNILISTNEVVKISDFGTSR--EWNEISTKMSFAGTVAWMAPEVIRNEPCSEKV 327
            ....|||||::.|||::.:.|.||:|||.:|  |.||.:.:......:.|.|||.|.....:.|.
Zfish   347 QRNYIHRDLRAANILVNKSLVCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINYGSFTIKS 411

  Fly   328 DIWSYGVVLWEMLTC-EIPYKDVDSSAIIWGV--GNNSLKLLVPSTCPEGFKLLVKLCWKSKPRN 389
            |:||:|::|.|:::. ..||..:.:..:|..:  |....:|   .:||:....::..|||:||.:
Zfish   412 DVWSFGILLTEIISYGRTPYPGMTNPEVIRALERGYRMQRL---DSCPQELYDIMLECWKNKPED 473

  Fly   390 RPSFRQILSHLDIAGPELLRKTEKQY 415
            ||:|..:.|.|:    :....||.||
Zfish   474 RPTFEYLQSVLE----DFYTATESQY 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	82/252 (33%)
hck	XP_005174178.1	SH3	58..109	CDD:473055
		SH2	113..215	CDD:472789
		PTKc_Hck	222..487	CDD:270658	87/274 (32%)