Protein Alignment wnd and si:ch73-340m8.2

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_002665190.3
• Gene: si:ch73-340m8.2 / 100332982
• ZFINID: ZDB-GENE-110411-209
• Length: 480
• Species: Danio rerio
• Alignment Length: 453
• Identity: 122/453 - (26%)
• Similarity: 199/453 - (43%)
• Gaps: 99/453 - (21%)

  Fly     8 LSKSRDDLVTAASRQQQQLHGRRR------------HHGSSPNLSLDQTDNLR------------ 48
            |:..:.|::......:..|:.|||            .||..|...:...|::.
Zfish    47 LNLRKGDILEVTGETEYWLYVRRRTAKTDKSKSFIEEHGYVPKDFVKPLDSVEAEPWYFENVKTR 111

  Fly    49 -RSMACLQ--------------DEFGHLGIAATDLP------FKSSDLDSPPRLQHHNNYAEITD 92
             .:..||.              ||..|..::..:.|      .|..:.|....|.||..:..:
Zfish   112 VEAKRCLLRPENKEGAFLVWKCDENNHYYLSVKNGPHARHYRIKQGENDQQFFLVHHTTFQSL-- 174

  Fly    93 SSAENTCQQRWPPHVGGAGAAFGHPDKPIGWMYGLLGCMK---PV---LSFIGKTGVIEVKSQRS 151
                ....:.:..|.||..|....            .|:|   ||   |||..|.
Zfish   175 ----RKLIEFYSKHEGGLCAKLHE------------ACVKLDQPVPQTLSFDSKC---------- 213

  Fly   152 EDWQIPFESITELEWLGSGAQGAVFSGRLKNET-VAVKKVKELK----ETDIKHLRKLDHENIIK 211
               :|...|:|:.:.||||....|:.|...|.| ||:|:.|.:.    :|:|:.::.|.||.::|
Zfish   214 ---EIDRSSLTKQQKLGSGEFADVWQGLWNNTTEVAIKEFKGVNYSDIQTEIEIMKDLHHERLLK 275

  Fly   212 FKGVCTQSPVFCIIMEFCPYGPLQNIL---KEEQVMLPSRLVSWSKQIALGMQYLHSHKIIHRDL 273
            ...|||.|...||:.|....|.|:..|   ||:|.:..|.::.::.||..||.|: .:||:||||
Zfish   276 LYAVCTTSQPMCIVTELMKNGSLKTFLLRHKEKQDLEFSLMLDFAIQITEGMIYI-ENKIVHRDL 339

  Fly   274 KSPNILISTNEVVKISDFG---TSREWNE-ISTKMSFAGTVAWMAPEVIRNEPCSEKVDIWSYGV 334
            ::.|||::..:..||:|||   .:|..|: ||:.:..  .|.|||||:..|...:.|.|:||:|:
Zfish   340 RAENILLTEMQSCKIADFGLAQVNRPGNQRISSDVRL--PVKWMAPEIFDNGEYTSKSDVWSFGI 402

  Fly   335 VLWEMLTC-EIPYKDVDSSAIIWGVGNNSLKLLVPSTCPEGFKLLVKLCWKSKPRNRPSFRQI 396
            :|.|::|. :.||...|..:.:.|:.... ::..|:.|||....::.||||:.|:.||:|.::
Zfish   403 LLTEIVTYGDDPYPGQDKMSCVRGIQRGE-RMPRPAGCPESLYGIMLLCWKANPKERPTFTEL 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	86/243 (35%)
si:ch73-340m8.2	XP_002665190.3	SH2	99..192	CDD:472789	15/98 (15%)
		Protein Kinases, catalytic domain	225..468	CDD:473864	86/244 (35%)