Protein Alignment wnd and ripk3

DIOPT Version :10

• Sequence 1: NP_649137.3
• Gene: wnd / 40143
• FlyBaseID: FBgn0036896
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_001343827.1
• Gene: ripk3 / 100004555
• ZFINID: ZDB-GENE-071115-4
• Length: 433
• Species: Danio rerio
• Alignment Length: 432
• Identity: 111/432 - (25%)
• Similarity: 188/432 - (43%)
• Gaps: 77/432 - (17%)

  Fly   167 LGSGAQGAVFSGR--LKNETVAVKKV--KELKETDIKHLRKL----DHENIIKFKGVC------T 217
            :|||..|.:|..|  |....||||.:  ||...:..:...:|    .:.|:::..||.      .
Zfish    24 VGSGGFGQIFRARHTLWGTDVAVKLLHYKEGSASSAQREAELMFDAGNSNVVRVLGVYEGRLGDP 88

  Fly   218 QSPVFC-IIMEFCPYGPLQNILKEEQVMLPSRL-VSWSKQIALGMQYLH--SHKIIHRDLKSPNI 278
            |.|:.| :::||...|.|:::|:......|..| :..:.|::|||.:||  :..|:|.|||..|:
Zfish    89 QRPLQCGLVLEFLARGSLEDLLQRLAAPPPCALALRMALQVSLGMNFLHQLTPPILHLDLKPSNV 153

  Fly   279 LISTNEVVKISDFGTSREWNEISTKMSF-----AGTVAWMAPEVIRN---EPCSEKVDIWSYGVV 335
            |:|.:...||:|||.||....:......     .||:::|.||.:::   :| |:..|::|||::
Zfish   154 LLSDSLDAKITDFGLSRVAENVCKYTGVNDEDEGGTLSYMPPEALQSSSYKP-SKAFDVYSYGIL 217

  Fly   336 LWEMLTCEIPYKDVDSSAIIWGVGNNSLKLLVPSTC--PEGFKLLVKL---CWKSKPRNRPSFRQ 395
            ||.::|.:.||..|.||.:.:.:.......|....|  .||...|:||   ||..:|..||||..
Zfish   218 LWSIITGKEPYSGVQSSLVRFRIPLGDRPDLASVDCSETEGLDELLKLMMQCWDQEPHRRPSFLD 282

  Fly   396 ILSHLD-IAGPELLRKTEKQYFETQKSWKEEVRSHLKEITQNGTNIHKYEQDLIKRRTAEWRHAQ 459
            .:..:. |......|..:..:...::...:|:.|.|:.:.             |.|:.......|
Zfish   283 CVHAITAIYTMHARRLNDDVHDVLEQLQDDEICSSLRSVQ-------------ISRKPHREVDPQ 334

  Fly   460 DIRMV------------YEDKLQKTNQLFFELSECMSQLQEKEKEIAERERKL--PGSGYKPNRR 510
            |:..|            |.:.:||         ||..:.......|.:.:|:.  |......:..
Zfish   335 DLSCVTGPAPQQETAAAYTETVQK---------ECSPRAAPPVGAIRKTQRQTSNPAVQVSMSNV 390

  Fly   511 FG------NTIRKMQHYRRRLNPAPAAIQQQSTTPDPETTPE 546
            ||      |::...|..|:|...||:|:...|:  .|:..|:
Zfish   391 FGVQIGNNNSMNITQKPRQRHRTAPSAVNTHSS--HPQNPPQ 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wnd	NP_649137.3	STKc_MAP3K12_13	167..403	CDD:270961	81/267 (30%)
ripk3	XP_001343827.1	Protein Kinases, catalytic domain	24..285	CDD:473864	81/261 (31%)